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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:19 PM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Loss Framed Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Testing Strategies for Weight Loss, II

NCT00739492
View directory record Official record
Conditions
Obesity
Interventions
financial incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 70 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Framing Messages for Smoking Cessation With Bupropion - 6

NCT00104598
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Bupropion, Smoking Abstinence Program
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Mobile Text Messaging to Reduce Problem Drinking

NCT01885312
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention, Assessment only
Behavioral · Other
Lead sponsor
Northwell Health
Other
Eligibility
21 Years to 65 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Oct 17, 2026, 11:19 PM EDT
Recruiting Not applicable Interventional

Sleep Promotion and Pediatric Hypertension

NCT06642246
View directory record Official record
Conditions
Insufficient Sleep, Hypertension
Interventions
Intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional

Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers

NCT03446170
View directory record Official record
Conditions
Tobacco Use
Interventions
Graphic cigarette warning labels, plain packaging
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 30 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interventions to Increase HBV Vaccinations in Sexually Transmitted Disease (STD) Clinics

NCT00739752
View directory record Official record
Conditions
Hepatitis B Virus
Interventions
Non-Framed-Offered, Non-Framed-Recommended, Gain-Framed-Offered, Gain-Framed-Recommended, Loss-Framed-Offered, Loss-Framed-Recommended
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
1,747 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 9, 2018 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Adolescent Investment In Diabetes Care

NCT04516694
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Financial incentive (gain), Financial incentive (loss)
Behavioral
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
12 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Results available

Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 2

NCT04110314
View directory record Official record
Conditions
Influenza, Respiratory Tract Infections
Interventions
Portal Reminders for Influenza Vaccination: Gain-framed, Portal Reminders for Influenza Vaccination: Loss-framed, Pre-commitment prompt
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Months and older
Enrollment
430,636 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gain and Loss Framed Text Messaging to Reduce Drinking Among Older Adults

NCT06126107
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Brief Normative Feedback, Loss-framed Text-messaging, Gain-framed Text-messaging
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
50 Years to 85 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional

New Technology and Child Health

NCT02622035
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Provision of information, Emotion induction, visual perceptual load
Behavioral
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving

NCT03335735
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive, Driving Impaired, Driving Under the Influence, Behavior, Drinking
Interventions
Loss-framed text message, Gain-Framed text message
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 17, 2026, 11:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children

NCT05703347
View directory record Official record
Conditions
Insufficient Sleep, Obesity
Interventions
Fixed sleep goal, Personalized sleep goal, Digital sleep health messaging without virtual study visit, Digital sleep health messaging with virtual study visit, Inactive Parent-Directed Loss-Framed Incentive, Active Parent-Directed Loss-Framed Incentive, Inactive Supportive Feedback, Active Supportive Feedback
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 12 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Decision-Framing in Psoriasis

NCT04136314
View directory record Official record
Conditions
Psoriasis Vulgaris, Psoriatic Arthritis, Psoriasis
Interventions
Decision-Framed Survey
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Behavioral Economic Incentives to Improve Glycemic Control Among Adolescents and Young Adults

NCT02568501
View directory record Official record
Conditions
Diabetes, Type 1 Diabetes
Interventions
Daily feedback, Financial incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
14 Years to 20 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 11, 2016 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination

NCT03856437
View directory record Official record
Conditions
Cervical Cancer, Anal Cancer, Penile Cancer
Interventions
HPV vaccination messages
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 99 Years
Enrollment
1,170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intern Health Study 2022 and 2023

NCT05436145
View directory record Official record
Conditions
Depression, Mood, Sleep, Physical Activity
Interventions
Intern Health Study behavioral change mobile notification
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
2,562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 17, 2026, 11:19 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Literacy and Smoking Risk Communications

NCT00684437
View directory record Official record
Conditions
Smoking
Interventions
Focus Group, Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 70 Years
Enrollment
494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Results available

Social and Financial Incentives to Increase Physical Activity Among Overweight and Obese Veterans

NCT03563027
View directory record Official record
Conditions
Physical Activity
Interventions
Social Incentive Gamification, Support Sponsor, Financial Incentive
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Financial Incentives and Nudges to Reduce Cellphone Use While Driving Among UBI Auto Policy Holders

NCT03833219
View directory record Official record
Conditions
Automobile Accident
Interventions
Weekly feedback, End of intervention period incentive, Loss-framed weekly incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older
Enrollment
2,108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 17, 2026, 11:19 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Improving Physical Activity and Cardiac Rehabilitation Attendance Using Technology and Behavioral Economics

NCT04304872
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Gamification, Loss-Framed Financial Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Economic Incentives and Cancer Health Risk Assessment

NCT03068052
View directory record Official record
Conditions
Cancer of the Colon
Interventions
No incentive, Incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years to 64 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 17, 2026, 11:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Strategies for Weight Loss

NCT05799846
View directory record Official record
Conditions
Obesity
Interventions
Standard Behavioral Weight Loss Intervention, PREVENT Behavioral Weight Loss Intervention, PROMOTE Behavioral Weight Loss Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 17, 2026, 11:19 PM EDT
Completed Not applicable Interventional

Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments

NCT03821103
View directory record Official record
Conditions
Opioid Use
Interventions
Training, Behavioral economic enhanced arm
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 17, 2026, 11:19 PM EDT
Enrolling by invitation Not applicable Interventional

Testing Alcohol Cancer Risk Messages

NCT07365813
View directory record Official record
Conditions
Alcohol, Cancer
Interventions
Text-only messages, AI-developed Neutral pictorial messages, AI-developed graphic pictorial messages
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
21 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 11:19 PM EDT