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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Low Carbohydrate diet + Exercise Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 20, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional

Nutritional Intervention for Endometriosis

NCT05175248
View directory record Official record
Conditions
Endometriosis
Interventions
Plant-based Intervention Group
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females

NCT07546591
View directory record Official record
Conditions
Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
Interventions
Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Oxalate and Innate Immunity in Kidney Stone Disease

NCT04051346
View directory record Official record
Conditions
Kidney Stone
Interventions
Low Oxalate Diet, High Oxalate Diet
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional

Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center

NCT06712797
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma, Intraductal Papillary Mucinous Neoplasm
Interventions
Physical Activity (PA), Nutrition (N)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional

Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial

NCT06976307
View directory record Official record
Conditions
Disabilities, Obesity and Overweight, Prediabetes
Interventions
High Carbohydrate Diet, Reduced Carbohydrate Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Diet Composition and Cardiometabolic Risk Reduction in Adults With SCI

NCT02630524
View directory record Official record
Conditions
Obesity, Spinal Cord Injuries, Diabetes
Interventions
eHealth Behavioral Lifestyle Intervention Device: Telecoach
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Sep 20, 2026, 2:55 PM EDT
Terminated Not applicable Interventional

Examining the Effects of Diet on Health in Prediabetes With an Online Program

NCT02188823
View directory record Official record
Conditions
Prediabetes
Interventions
Low carbohydrate diet
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Sep 20, 2026, 2:55 PM EDT
Recruiting Phase 3 Interventional

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

NCT07754461
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Placebo, Survodutide
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
89
States / cities
Birmingham, Alabama • Gilbert, Arizona • Paradise Valley, Arizona + 81 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Withdrawn No phase listed Observational

Energy Expenditure and Quality of Life in Epilepsy

NCT04546711
View directory record Official record
Conditions
Epilepsy
Interventions
Ketogenic Diet
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional

The Healthy Eating and Active Living to Reverse Diabetes Pilot Study

NCT07316569
View directory record Official record
Conditions
Diabete Type 2, Diabetes, Overweight , Obesity
Interventions
Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virta Intervention in CommuniTies in cOloRado (VICTOR-Pilot)

NCT04807218
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Virta Health
Behavioral
Lead sponsor
Colorado Prevention Center
Other
Eligibility
18 Years to 79 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Craig, Colorado • Lamar, Colorado • Salida, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

(R33 Phase) DELISH Study: Diabetes Education to Lower Insulin, Sugars, and Hunger

NCT03837405
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Carbohydrate-restricted diet, Mindfuless
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Recruiting Phase 2 Interventional

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

NCT05082519
View directory record Official record
Conditions
B-cell Acute Lymphoblastic Leukemia, Obesity
Interventions
IDEAL2 Intervention
Behavioral
Lead sponsor
Etan Orgel
Other
Eligibility
7 Years to 25 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
16
States / cities
Los Angeles, California • Orange, California • San Francisco, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Energy Dense Fueling for Cold-Weather Operations

NCT07489690
View directory record Official record
Conditions
Cold Exposure
Interventions
High Fat, High Carbohydrate
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bitter Taste and Weight Loss in Women

NCT01856660
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Low-Carbohydrate Diet, Low-fat Diet
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 20, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional

Fitness and Nutrition in Glioma

NCT06665373
View directory record Official record
Conditions
Malignant Glioma
Interventions
Modified Atkins Diet, Fitness Program
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional

The Feasibility of a Diet and Exercise Intervention in Diabetics During Treatment for Non-muscle Invasive Bladder Cancer

NCT02716623
View directory record Official record
Conditions
Bladder Cancer, Diabetes Mellitus
Interventions
CR diet, Exercise
Other · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 20, 2026, 2:55 PM EDT
Not listed Phase 2 Interventional

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea

NCT02069197
View directory record Official record
Conditions
Obesity, Diabetes, Obstructive Sleep Apnea
Interventions
Ketogenic diet, Orlistat, Standardized diet
Other · Drug
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Dynamically Tailored Behavioral Interventions in Diabetes

NCT04226027
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
T2.coach
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 20, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Sep 20, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Renal Metabolism of Glycolate to Oxalate

NCT04437225
View directory record Official record
Conditions
Healthy
Interventions
Low oxalate controlled Diet, Primed, continuous intravenous infusion of 13C2-Glycolate, Bolus intravenous infusion of 13C2-Glycolate, Oral bolus administration of 13C2-Glycolate
Dietary Supplement · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 20, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional

Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

NCT06081543
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Ketogenic diet, Low-fat Mixed diet
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 20, 2026, 2:55 PM EDT