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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Low Fat Diet plus exercise Clear all
Completed Not applicable Interventional

Rural Lifestyle Eating and Activity Program (Rural LEAP)

NCT02054624
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle intervention, Health education control, Individual, All Groups
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 75 Years
Enrollment
631 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
14
States / cities
Bronson, Florida • Bunnell, Florida • Cross City, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 26, 2026, 1:48 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

NCT06412510
View directory record Official record
Conditions
Ovarian Cancer, Epithelial Ovarian Cancer, Pancreatic Adenocarcinoma
Interventions
Prehabilitation
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Composition, Weight Control, and Breast Carcinogenesis

NCT01315483
View directory record Official record
Conditions
Breast Cancer
Interventions
Weight Loss Dietary Pattern
Other
Lead sponsor
Colorado State University
Other
Eligibility
21 Years and older · Female only
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promotora-Led Intervention for Metabolic and Mental Health

NCT03372018
View directory record Official record
Conditions
PreDiabetes, Obesity, Metabolic Disease, Body Weight Changes, Diabetes Mellitus
Interventions
Promotora-led Intervention (PLI), Usual care (UC)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Sep 26, 2026, 1:48 AM EDT
Not listed Not applicable Interventional

UCLA Breast Cancer Survivor Health Promotion Research Study

NCT05113485
View directory record Official record
Conditions
Breast Cancer
Interventions
Diabetes Prevention Program-based lifestyle change intervention (DPP), Highly Microbiota-Accessible Foods (HMAFs) intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2022 · Synced Sep 26, 2026, 1:48 AM EDT
Not listed Not applicable Interventional

Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease

NCT04606420
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lifestyle medicine
Behavioral
Lead sponsor
Preventive Medicine Research Institute
Other
Eligibility
45 Years to 90 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
San Diego, California • Sausalito, California • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Daily Steps on Fat Metabolism

NCT03697382
View directory record Official record
Conditions
Atherosclerosis, Metabolic Syndrome
Interventions
Very Low Steps, Low Steps, Moderate Steps
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Effect of Weight Loss on Cardiovascular Disease Risk Factors in Obese Women

NCT01353001
View directory record Official record
Conditions
Obesity, Cardiovascular Diseases
Interventions
Diet, Diet Plus Aerobic Training, Diet plus Resistance Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 4, 2016 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers

NCT02695433
View directory record Official record
Conditions
Pre-diabetes, Metabolic Syndrome
Interventions
Active, Control
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 60 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Phase 2Phase 3 Interventional

Low Glycemic Load Diets in Latino Children at Risk for Type 2 Diabetes

NCT01068197
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Low Glycemic Load Diet versus Low Fat Diet
Behavioral
Lead sponsor
Nazrat Mirza
Other
Eligibility
7 Years to 14 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2014 · Synced Sep 26, 2026, 1:48 AM EDT
Active, not recruiting Not applicable Interventional

Century Trial, a Randomized Lifestyle Modification Study for Management of Stable Coronary Artery Disease

NCT00756379
View directory record Official record
Conditions
Cardiovascular Disease, Atherosclerosis, Coronary Artery Disease, Coronary Stenosis
Interventions
Comprehensive therapy program for risk factor modification
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
1,085 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Effect of Exercise on Acute High-fat Overfeeding

NCT07633704
View directory record Official record
Conditions
Insulin Sensitivity/Resistance
Interventions
High Fat Overfeeding, High Fat Overfeeding + Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
20 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Considering Patient Diet Preferences to Optimize Weight Loss

NCT01152359
View directory record Official record
Conditions
Obesity
Interventions
Choice, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 74 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

The Effects of Diet and Exercise Interventions in Peripheral Artery Disease

NCT03845036
View directory record Official record
Conditions
Claudication, Peripheral Artery Disease
Interventions
DASH Diet plus Home-Based Exercise, Home-Based Exercise
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrient Timing Following Resistance Exercise

NCT01674049
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Immediate Nutrition, Nutrition 3 hours Post-Bout, Resistance Exercise
Dietary Supplement · Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 28, 2012 · Synced Sep 26, 2026, 1:48 AM EDT
Active, not recruiting Not applicable Interventional

Nutritional Intervention for Endometriosis

NCT05175248
View directory record Official record
Conditions
Endometriosis
Interventions
Plant-based Intervention Group
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Low-calorie Diet in Isolated Impaired Fasting Glucose

NCT06451055
View directory record Official record
Conditions
Isolated Impaired Fasting Glucose
Interventions
Low-calorie diet, Routine dietary and physical activity habits
Behavioral
Lead sponsor
Emory University
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Effect of Exercise and Diet on Inflammation in Hypertensive Individuals

NCT00338572
View directory record Official record
Conditions
Hypertension
Interventions
Exercise Program, Combined Exercise and Diet Program
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
25 Years to 60 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2012 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
View directory record Official record
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stroke Health and Risk Education (SHARE)

NCT01378780
View directory record Official record
Conditions
Stroke, Hypertension
Interventions
Educational intervention for diet and physical activity, Educational message on skin cancer awareness
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Motivational Interviewing for Weight Loss With Young Adults

NCT01899625
View directory record Official record
Conditions
Obesity
Interventions
Brief Behavioral Weight Loss (BWL), Motivation Enhanced BWL
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preference and Vegetarian Diet in Weight Loss Treatment

NCT00330629
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Standard Behavioral Treatment, SBT+LOV
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 3, 2016 · Synced Sep 26, 2026, 1:48 AM EDT