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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:04 AM EDT

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Showing 25–48 of 240 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Low Level Light Therapy Clear all
Completed Not applicable Interventional Results available

Light Therapy for Moderate Traumatic Brain Injury

NCT02233413
View directory record Official record
Conditions
Moderate Traumatic Brain Injury (TBI)
Interventions
Active LLLT helmet application, Non-active LLLT helmet application
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue

NCT03461731
View directory record Official record
Conditions
Muscle Fatigue
Interventions
Control, 800 nm laser, combination laser, 905 nm laser
Device
Lead sponsor
College of Charleston
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional

Clinical Trials of Two Non-drug Treatments for Chronic Depression

NCT00006172
View directory record Official record
Conditions
Mood Disorders, Depressive Disorders, Depression, Chronic Depression
Interventions
Bright light box, High-output negative ion generator, Low-output negative ion generator
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
2
States / cities
Middletown, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Sep 30, 2026, 1:04 AM EDT
Recruiting Not applicable Interventional

Low Level Light Therapy & Skin Pigmentation

NCT07173530
View directory record Official record
Conditions
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Interventions
Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Terminated Not applicable Interventional

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional

Photobiomodulation Therapy in Persons With Multiple Sclerosis

NCT03691766
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Photobiomodulation Therapy, Placebo
Other
Lead sponsor
Marquette University
Other
Eligibility
20 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Sep 30, 2026, 1:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Treating Meibomian Gland Disease in a Pediatric Population

NCT07229001
View directory record Official record
Conditions
Dry Eye Disease, Meibomian Gland Disease
Interventions
Low level light treatment, warm compress and artificial tear
Other
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Brain Substrates for Cardiovascular Stress Physiology

NCT05298956
View directory record Official record
Conditions
Stress Reaction
Interventions
Low-level laser therapy (LLLT)
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Low Level Laser Therapy for Body Contouring

NCT00738426
View directory record Official record
Conditions
Body Contouring
Interventions
Erchonia ML Scanner (MLS), Sham device
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Palm Beach Gardens, Florida • Marion, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 30, 2026, 1:04 AM EDT
Recruiting Not applicable Interventional

Photobiomodulation for Management of Temporomandibular Disorder Pain

NCT05916235
View directory record Official record
Conditions
Pain Related to TMD
Interventions
THOR® laser system
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Investigating Near-Threshold Perception During Anesthetic Sedation

NCT06403852
View directory record Official record
Conditions
Propofol, Anesthesia, fMRI
Interventions
Functional Magnetic Resonance Imaging (fMRI) with propofol
Combination Product
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional

Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients

NCT02119897
View directory record Official record
Conditions
Oropharyngeal Mucositis, Myeloablative Hematopoietic Cell Transplantation, Low Level Light Therapy
Interventions
Low Level Light Therapy
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
4 Years to 25 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Sep 30, 2026, 1:04 AM EDT
Not yet recruiting Early Phase 1 Interventional

Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of Pruritus

NCT07450716
View directory record Official record
Conditions
Pruritus
Interventions
Light-emitting diode (LED) Photobiomodulation (PBM) device, Placebo
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 30, 2026, 1:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function

NCT04760054
View directory record Official record
Conditions
Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
Interventions
HUBOD, Active Comparator, Control Condition
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional

LED Treatment to Improve Cognition and Promote Recovery in TBI

NCT02404402
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
LED, sham LED
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

NCT03972527
View directory record Official record
Conditions
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
Interventions
Photobiomodulation, Routine Oral Care and Analgesia
Device · Other
Lead sponsor
MuReva Phototherapy Inc.
Industry
Eligibility
22 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-level Laser and Lifestyle Modifications

NCT05083442
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Low Level Laser Therapy, Sham (placebo)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Results available

Assessment Of Infrared Photobiotherapy for Improved Wound Healing

NCT00426166
View directory record Official record
Conditions
Wound Healing
Interventions
Low Level Laser Therapy
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Not yet recruiting Not applicable Interventional

Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

NCT07832422
View directory record Official record
Conditions
Low Back Pain, Myofascial Pain Syndromes
Interventions
Ischemic Compression, Low-Level Laser Therapy, Exercise Program, Sham Low-Level Laser Therapy
Other · Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 30, 2026, 1:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of Repeated Low-level Red-light Therapy in Myopia Control

NCT05606237
View directory record Official record
Conditions
Myopia
Interventions
Low-level Red Light Therapy Device
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
8 Years to 13 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 30, 2026, 1:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints

NCT07279441
View directory record Official record
Conditions
Cochlear Implant Users
Interventions
Experiment 1: Syntactic and Semantic Context, Experiment 2: False Hearing and Context Overuse, Experiment 3: Two-Sentence Problem, Experiment 4: Cascading Effects on Discourse Comprehension, Experiment 5: Self-Paced Discourse Comprehension, Experiment 6: Clinical Application
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Waltham, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effect of Dopamine on Diabetic Retinopathy

NCT02706977
View directory record Official record
Conditions
Diabetes
Interventions
Low Dose Sinemet CR, High Dose Sinemet CR, RETeval Electroretinogram (ERG) Testing, Contrast Sensitivity Testing, Visual Acuity Testing
Drug · Device · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Over-The-Counter Use of Low Level Laser Light Therapy for Body Contouring of the Waist, Hips and Thighs

NCT02167867
View directory record Official record
Conditions
Circumference Reduction
Interventions
Lay End Users, Treatment Subject Group
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Sep 30, 2026, 1:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Differential Effects of Photobiomodulation on Sleep and Performance

NCT05116605
View directory record Official record
Conditions
Sleep Quality
Interventions
Photobiomodulation (PBM)
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Sep 30, 2026, 1:04 AM EDT