Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 11:15 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 392 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Low calorie diet Clear all

Conditions: Sweetness Liking Adaptation
Interventions: Flavored carbonated soft drink (CSD); Other
Lead sponsor: PepsiCo Global R&D; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: NAFLD, Fatty Liver, Obesity, Metabolic Syndrome
Interventions: Diet Intervention; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 11 Years to 17 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity
Interventions: Roux-En-Y Gastric Bypass, Low-calorie Diet; Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bipolar I Disorder, Psychosis, Schizoaffective Disorder
Interventions: Ketogenic diet, Dietary Guidelines for Americans; Other
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 45 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Genetics, Obesity
Interventions: Diet modification; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 20 Years to 45 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Lung Injury, Particulate Matter Inhalation Injury
Interventions: Low-Calorie Mediterranean Diet, Technology based monitoring and behavioral participation, Usual care group; Dietary Supplement · Combination Product · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 90 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: Video Conference Meetings, In-person Meetings, Enhanced Stop Light Diet, Physical Activity; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers
Interventions: BAY2927088, Esomeprazole, Food; Drug · Other
Lead sponsor: Bayer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Human Immunodeficiency Virus, Metabolic Syndrome
Interventions: Intermittent fasting, Standard of Care; Behavioral · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Anorexia Nervosa, Metabolic Syndrome
Interventions: Calorie controlled diet; Behavioral
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 2
States / cities: New York, New York

Conditions: Weight Loss, Starvation
Interventions: Caloric Restriction, Protein, Exercise, Calcium and Vitamin D, Maltodextrin; Other · Dietary Supplement
Lead sponsor: University of Nebraska Lincoln; Other
Eligibility: 19 Years to 30 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Weight Loss
Interventions: Caloric restriction, high protein, Caloric restriction; normal protein, Nutrition Education; Behavioral
Lead sponsor: Rutgers University; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Diabetes
Interventions: Calorie Restriction, Exercise, Calorie Restriction and Exercise; Other
Lead sponsor: St. Louis University; Other
Eligibility: 45 Years to 65 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Diabetes Mellitus, Obesity
Interventions: Low carbohydrate ketogenic diet, Orlistat, Low-fat diet; Behavioral · Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 69 Years
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cystic Fibrosis, Cystic Fibrosis-related Diabetes
Interventions: Low-added sugar, high-fat diet, High-added sugar, high-fat CF diet; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obesity
Interventions: Behavioral lifestyle/weight-loss intervention; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 25 Years and older
Enrollment: 163 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2004
U.S. locations: 1
States / cities: Stanford, California

Conditions: Caloric Intake and Energy Metabolism
Interventions: Digital Photography of Foods, doubly labeled water, IDEEA, low-calorie diet, Actical, Sensewear Armband; Behavioral · Other · Device
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: Ketogenic diet, Low-fat Mixed diet; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obesity
Interventions: CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet; Drug · Behavioral
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 699 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 9
States / cities: La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more

Conditions: Breast Carcinoma
Interventions: Behavioral Dietary Intervention; Behavioral
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nutritional and Metabolic Diseases
Interventions: Diet Soda; Other
Lead sponsor: George Washington University; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions: Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling; Other · Behavioral · Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 40 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Aging
Interventions: Caloric restriction; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 25 Years to 46 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Elevated Blood Pressure, Hypertension
Interventions: Dietitian-Assisted DASH groceries, Self-directed shopping; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Liking Adaptation to Beverages of Varying Sweetness Levels After Prolonged Exposure

Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens With Metabolic Syndrome

Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

Inherited and Environmental Risks Acting on Body Weight

Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial

Remote Delivery of Weight Management for Adults With IDD

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

2-5 Intermittent Caloric Restriction in HIV

Does Metabolic Syndrome Exist in Anorexia Nervosa?

Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity

The Effect of Severe Weight Loss and Protein Intake on Bone

Caloric Restriction, Exercise, and Glucoregulation in Humans

A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss

FEED-Cystic Fibrosis (FEED-CF)

Promoting Long-term Behavior Change to Reduce CVD Risk

Assessment of Energy Balance

Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients

CAREFOR: Precision Medicine Driving Precision Nutrition for the Treatment of NeoAdjuvant Breast Cancer

Low-calorie Sweeteners and Adipose Signaling

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

CALERIE Phase II Ancillary: Metabolic

Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension