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ClinicalTrials.gov public records Last synced Oct 13, 2026, 7:10 PM EDT

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Showing 145–168 of 171 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Low calorie low fat diet Clear all
Recruiting Not applicable Interventional

Daily Eating Patterns for Total Health Study

NCT06455995
View directory record Official record
Conditions
Obesity
Interventions
DEPTH, DEPTH-Morning, DEPTH-Evening
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
25 Years to 60 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 13, 2026, 7:10 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Muscle Insulin Resistance in Aging (Mirage)

NCT02230839
View directory record Official record
Conditions
Insulin Resistance, Sarcopenia
Interventions
Exercise, Energy Restriction-Induced Weight Loss
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
65 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Quality Protein for Assisting With Weight Loss

NCT03085511
View directory record Official record
Conditions
Obesity
Interventions
Egg breakfast (EB), Weight Loss Counseling, Weight Loss Diet, Cereal Breakfast (CB)
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss

NCT03515889
View directory record Official record
Conditions
Weight Loss
Interventions
Ideal Protein Weight Loss Method, Standard Weight Loss
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
22 Years to 79 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bogalusa, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Weight Loss on Hepatic and Muscle Lipid Content and on Insulin Sensitivity on Obese Adolescents With NAFLD

NCT00585299
View directory record Official record
Conditions
Fatty Liver, Insulin Resistance
Interventions
Low-fat diet, Traditional diet
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet

NCT03266536
View directory record Official record
Conditions
Small Intestine Bacteria
Interventions
Western diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)

NCT00928005
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes, Prediabetes
Interventions
Weight loss diet, Weight loss diet plus exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preference and Vegetarian Diet in Weight Loss Treatment

NCT00330629
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Standard Behavioral Treatment, SBT+LOV
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 4, 2016 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism

NCT03878108
View directory record Official record
Conditions
Healthy, Healthy Volunteers
Interventions
LCHF diet, LFHC diet
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Obesity, Iron Regulation and Colorectal Cancer Risk

NCT03548948
View directory record Official record
Conditions
Colon Inflammation, Iron Malabsorption, Obesity, Diet Modification
Interventions
High heme iron diet, Low iron diet, Plant-based high non-heme iron diet
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years to 70 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

Effect of Low Carbohydrate Versus Low Fat Diet in the Treatment of Dyslipidemia in Obese Children With Metabolic Syndrome

NCT03937960
View directory record Official record
Conditions
Metabolic Syndrome, Obesity, Dyslipidemias
Interventions
Carbohydrate restricted group, Standard low fat diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 13, 2026, 7:10 PM EDT
Terminated Phase 1 Interventional

A Phase 1 Study of Oprozomib to Assess Food Effect, Drug-Drug Interaction With Midazolam, and Safety and Tolerability in Patients With Advanced Malignancies

NCT02244112
View directory record Official record
Conditions
Advanced Non-Central Nervous System (CNS) Malignancies
Interventions
Oprozomib, Midazolam
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
7
States / cities
Aurora, Colorado • Atlanta, Georgia • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Weight Loss Intervention in Women With PCOS

NCT03677362
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Overweight and Obesity
Interventions
Weight loss intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 42 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Understanding the Paradoxical Rise in Blood Glucose in the Context of a Low-carbohydrate Diet

NCT07713316
View directory record Official record
Conditions
Elevated Blood Glucose, Low-carbohydrate Diet
Interventions
Carbohydrate Drink, Fat Drink, Protein Drink
Dietary Supplement
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Characterization of Bile Acid Pathway in Obesity

NCT03341052
View directory record Official record
Conditions
Obesity
Interventions
Normal Diet, High Fat Diet, Low Fat Diet
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eat Well for Life: A Weight Loss Maintenance Study

NCT01849627
View directory record Official record
Conditions
Obesity
Interventions
Low-ED, Energy Balance
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 70 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Diet Study on Ulcerative Colitis

NCT04147598
View directory record Official record
Conditions
Ulcerative Colitis
Interventions
LFD, SAD
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 13, 2026, 7:10 PM EDT
Not listed Not applicable Interventional

UCLA Breast Cancer Survivor Health Promotion Research Study

NCT05113485
View directory record Official record
Conditions
Breast Cancer
Interventions
Diabetes Prevention Program-based lifestyle change intervention (DPP), Highly Microbiota-Accessible Foods (HMAFs) intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Composition, Weight Control, and Breast Carcinogenesis

NCT01315483
View directory record Official record
Conditions
Breast Cancer
Interventions
Weight Loss Dietary Pattern
Other
Lead sponsor
Colorado State University
Other
Eligibility
21 Years and older · Female only
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.

NCT05630677
View directory record Official record
Conditions
Healthy Volunteers
Interventions
AZD5055 solution for infusion, AZD5055 oral suspension, AZD5055 film-coated tablet, Rabeprazole, Delayed-release tablet
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Brooklyn, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Regulation of FGF21 by Nutritional Challenges

NCT00968747
View directory record Official record
Conditions
Fasting, Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions
Fasting, Diet, oral carbohydrate challenge
Behavioral · Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

NCT06378658
View directory record Official record
Conditions
Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers
Interventions
BAY2927088, Esomeprazole, Food
Drug · Other
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2024 · Synced Oct 13, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.

NCT06449287
View directory record Official record
Conditions
Ketogenic Diet, Weight Loss
Interventions
Diet, Blood Draw, Ketone/Glucose Monitoring, Body Composition, Urine Analysis, Neuropsychological Measures - ANAM
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 13, 2026, 7:10 PM EDT