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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:38 PM EDT

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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Low dose THC marijuana Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Dronabinol (Oral THC) on Cannabis Use

NCT01394185
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Dronabinol 120mg/day, Placebo, Dronabinol 240mg/day
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 3, 2017 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment

NCT04931095
View directory record Official record
Conditions
Cannabis Intoxication, Alcohol Intoxication
Interventions
Cannabis, Alcohol
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Differences in Cannabis Impairment and Its Measurement Due to Route of Administration

NCT03122691
View directory record Official record
Conditions
Behavioral Pharmacology of Cannabis
Interventions
cannabis
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 20, 2026, 5:38 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

NCT02404688
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active delta-9-THC, Placebo, Active Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers

NCT00743119
View directory record Official record
Conditions
Pain Threshold, Mood
Interventions
Placebo capsules, Inactive marijuana (0% THC), Low dose Dronabinol, High dose Dronabinol, Low THC marijuana, High THC marijuana
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

NCT05602649
View directory record Official record
Conditions
Cannabis Use
Interventions
Cannabis, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 1 Interventional

Impact of Daily Oral Cannabis Doses in Patients With Cancer

NCT06601218
View directory record Official record
Conditions
Cancer, Cancers, Pain
Interventions
Oral cannabis low THC, Placebo Comparator, Oral cannabis high THC, Oral cannabis THC/CBD
Drug
Lead sponsor
Shanna Babalonis, PhD
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Inhaled Cannabis on Driving Performance

NCT01620177
View directory record Official record
Conditions
Alcohol Drinking, Cannabis
Interventions
Alcohol(oral) and placebo, Cannabis(THC)(Inhaled) and Placebo
Drug
Lead sponsor
Gary R Gaffney
Other
Eligibility
21 Years to 55 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations

NCT03191084
View directory record Official record
Conditions
Marijuana Impairment
Interventions
Low Dose THC Marijuana, High Dose THC Marijuana, Placebo Marijuana
Drug
Lead sponsor
Yale University
Other
Eligibility
20 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neuroscience of Marijuana Impaired Driving

NCT02757313
View directory record Official record
Conditions
Marijuana Impairment
Interventions
Low dose THC marijuana, High dose THC marijuana, Placebo marijuana
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

NCT05999383
View directory record Official record
Conditions
THC, Cannabis, Cannabis Use, Cannabis Smoking, Tobacco Use, Vaping
Interventions
Cannabis, Nicotine, Pax Loose Leaf Vaporizer, Placebo Marijuana
Drug · Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Results available

A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy.

NCT00530764
View directory record Official record
Conditions
Palliative Care, Pain, Cancer
Interventions
Sativex Low Dose, Sativex Medium Dose, Sativex High Dose
Drug
Lead sponsor
GW Pharmaceuticals Ltd
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
23
States / cities
Tuscaloosa, Alabama • Casa Grande, Arizona • Fountain Valley, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Vaporized Marijuana on Neuropathic Pain

NCT01037088
View directory record Official record
Conditions
Neuropathic Pain, Reflex Sympathetic Dystrophy, Peripheral Neuropathy, Post-herpetic Neuralgia, Spinal Cord Injury, Multiple Sclerosis
Interventions
Mild dose cannabis, Low dose cannabis, Cannabis
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 20, 2026, 5:38 PM EDT
Terminated Phase 3 Interventional Results available

Cannabidiol and Management of Endometriosis Pain

NCT04527003
View directory record Official record
Conditions
Endometriosis, CBD, Pelvic Pain
Interventions
Cannabidiol (CBD) Extract, Norethindrone Acetate, Placebo
Drug · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of Smoked Marijuana on Neuropathic Pain

NCT00254761
View directory record Official record
Conditions
Neuropathic Pain
Interventions
Cannabis
Drug
Lead sponsor
Center for Medicinal Cannabis Research
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2008 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Results available

Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

NCT02460692
View directory record Official record
Conditions
Cannabis, Low Back Pain, Neuropathic Pain
Interventions
Placebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
19 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on E-Cigarette Use Behavior

NCT06609109
View directory record Official record
Conditions
Cannabis Use, Tobacco Use, Electronic Cigarette Use
Interventions
THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations

NCT04856566
View directory record Official record
Conditions
Marijuana Impairment, Alcohol Impairment
Interventions
Low Marijuana, Hash, THC, or Grass, High Marijuana, Hash, THC, or Grass, Placebo, 0.05 BAC Alcohol, 0.08 BAC Alcohol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

High Potency Cannabis: Acute and Protracted Effects

NCT06859723
View directory record Official record
Conditions
Abuse Cannabis, Pain, Pharmacokinetics
Interventions
Placebo Comparator: Placebo, Low dose THC, High dose THC
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on Cigarette Use Behavior

NCT06609083
View directory record Official record
Conditions
Cannabis Use, Tobacco Use, Cigarette Smoking
Interventions
THC 30mg, THC 5mg, THC 0mg, Cigarette Full Nicotine, Cigarette Reduced Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

NCT02709954
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active inhaled delta-9-THC, Placebo, Active Oral Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cannabinoids and Cerebellar-Motor Functioning

NCT01853020
View directory record Official record
Conditions
Cannabis, Psychotic Disorders
Interventions
THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Low-dose Naltrexone in Combination With a Range of Smoked Marijuana

NCT00743145
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Inactive Marijuana (0% THC), Active Marijuana (5.5% THC), Active Marijuana (6.2% THC), Naltrexone, Placebo naltrexone
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2018 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cannabinoids, Neural Synchrony, and Information Processing

NCT00708994
View directory record Official record
Conditions
Cannabis, Psychotic Disorders
Interventions
THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 20, 2026, 5:38 PM EDT