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Conditions: Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions: Adapted Hatha Yoga, Low-Impact Exercise; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Aging, Sarcopenia, Disability Physical, Cardiovascular Diseases, Insulin Resistance, Diabetes Mellitus
Interventions: Exercise Intervention; Behavioral
Lead sponsor: Louisiana State University and A&M College; Other
Eligibility: 65 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Baton Rouge, Louisiana

Conditions: Prostate Cancer
Interventions: exercise intervention, nutritional supplementation, quality-of-life assessment, questionnaire administration, pharmacological study, laboratory biomarker analysis; Behavioral · Dietary Supplement · Procedure + 1 more
Lead sponsor: University of Southern California; Other
Eligibility: 50 Years and older · Male only
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Sickle Cell Anemia in Children
Interventions: Low systemic strength training, Moderate systemic exercise; Behavioral
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 12 Years to 17 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Depression, Anxiety, Emotion Regulation
Interventions: Common Elements Toolbox, Doing What Matters in Times of Stress: An Illustrated Guide, Guided self-help; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 275 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Localized Lung Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8
Interventions: Biospecimen Collection, Electronic Health Record Review, Medical Device Usage and Evaluation, Questionnaire Administration, Respiratory Muscle Training, Sham Intervention; Procedure · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Acute Coronary Syndrome, Fear Anxiety, Physical Inactivity
Interventions: Reducing Exercise Sensitivity with Exposure Training; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Low Back Pain
Interventions: SMT, Mobilizing Exercises, Activation Exercises, SMT extended; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 60 Years
Enrollment: 273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Major Depressive Disorder
Interventions: High Dose Resistance Exercise Training, Low Dose Resistance Exercise Training Group; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: Ames, Iowa • Madison, Wisconsin

Conditions: Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Recurrent Adult Acute Myeloid Leukemia, Untreated Adult Acute Myeloid Leukemia
Interventions: quality-of-life assessment, counseling intervention, exercise intervention, educational intervention, standard follow-up care; Procedure · Other · Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 60 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Chronic Pain
Interventions: 6 week aerobic exercise intervention, Placebo, Morphine, naloxone; Behavioral · Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 2
States / cities: Chicago, Illinois • Nashville, Tennessee

Conditions: Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities, Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile, Changes Within Adipose Tissue in Response to Exercise at the Three Different Intensities
Interventions: Low intensity exercise session, Moderate intensity exercise session, High intensity exercise session; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 40 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cancer, Chronic Stress, Autonomic Dysfunction
Interventions: Hight intensity interval training, Cyclic Hyperventilation with Retention; Behavioral
Lead sponsor: University of Northern Colorado; Other
Eligibility: 18 Years to 50 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Greeley, Colorado

Conditions: Ataxia, Spino Cerebellar Degeneration, Spinocerebellar Ataxias
Interventions: Aerobic Training, Balance Training; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
Interventions: Functional Resistance Training, Stretching, Delayed Functional Resistance Training; Other
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 65 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Parkinson's Disease
Interventions: High intensity exercise and balance training, Usual care arm exercise; Other
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 45 Years to 85 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Gestational Diabetes Mellitus, Gestational Diabetes Mellitus in Pregnancy, Insulin Resistance
Interventions: Acute exercises sessions with different exercise types and intensities; Behavioral
Lead sponsor: University of Central Arkansas; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Conway, Arkansas

Conditions: Lung Cancer
Interventions: Aerobic Training, Progressive Stretching, Resistance Training, Aerobic and Resistance Training; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Injuries, Patellofemoral Pain Syndrome, Iliotibial Band Syndrome
Interventions: Strength and Coordination Training, Walking; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: Plyometric Exercise; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 15 Years to 30 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions: Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage; Device · Dietary Supplement
Lead sponsor: Embry-Riddle Aeronautical University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Obesity, Pre-hypertension, Hypertension
Interventions: L-citrulline supplementation, Whole Body Vibration Training; Dietary Supplement · Other
Lead sponsor: Florida State University; Other
Eligibility: 50 Years to 70 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Traumatic Brain Injury
Interventions: aerobic exercise, stretching/toning; Other
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Knee Osteoarthritis
Interventions: Hybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer; Device
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 40 Years to 85 Years · Female only
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Kansas City, Kansas

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Pilot Trial for Adults With Acquired Brain Injury

Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health

Resistance Training and Protein Supplementation for Prostate Cancer Survivors

Low Systemic/High Local Exercise Load in Peds SCD

Low-intensity Stepped Care for Internalizing Distress

New York Better Breathing Study

The Reducing Exercise Sensitivity With Exposure Training (RESET) Study

Optimization of Spinal Manipulative Therapy Protocols

RESISTance Exercise for Depression Trial

Symptom-Adapted Physical Activity Intervention in Minimizing Physical Function Decline in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function

Skeletal Muscle and Adipose Tissue Responses After Acute Exercise: Comparing Effects of Three Different Intensities

Can You Breathe Your Way To Better Health?

Ataxia and Exercise Disease Using MRI and Gait Analysis

Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial

High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease

Prenatal Exercise and Glucose Regulation

Lung Cancer Exercise Training Study

Effect of Strength and Coordination Training on Biomechanics and Injury in New Runners

Anterior Cruciate Ligament Reconstruction and Plyometric Exercise

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Whole Body Vibration Combined With L-citrulline Supplementation on Cardiovascular Function and Body Composition

The Effect of Aerobic Exercise on Mild Traumatic Brain Injury

Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study)