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ClinicalTrials.gov public records Last synced Sep 8, 2026, 5:47 PM EDT

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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Low-Load Resistance Training Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors

NCT07460609
View directory record Official record
Conditions
Healthy Ageing
Interventions
Blood Flow Restriction Training Exercise, Health Education
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

NCT05177952
View directory record Official record
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

NCT07135583
View directory record Official record
Conditions
Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Incomplete Spinal Cord Injury
Interventions
Active Comparator: Single Intervention 1, Active Comparator: Single Intervention 2, Respiratory Resistance Exercise
Other · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Training in Rehabilitation Patients

NCT02174770
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
Interventions
Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.

NCT07130812
View directory record Official record
Conditions
Low Back Pain
Interventions
blood flow restriction, Heavy load resistance training
Other
Lead sponsor
Loma Linda University
Other
Eligibility
13 Years to 20 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Low-load Resistance Training With Blood Flow Restriction in People With Parkinson's Disease

NCT05806775
View directory record Official record
Conditions
Parkinson Disease
Interventions
Low-load resistance training with blood flow restriction
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

NCT07223437
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Blood Flow Restriction Cuff System, Low-load Resistance Training, High-load Resistance Training
Behavioral
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Low Versus High Load Training and Parkinson's Disease

NCT07378813
View directory record Official record
Conditions
Activity, Motor
Interventions
Low-Load Resistance Training, High-Load Resistance Training
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis

NCT04633759
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Blood Flow Restriction Exercise
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Not yet recruiting Not applicable Interventional

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy

NCT07781709
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Measurement of oxyhemoglobin and deoxyhemoglobin concentration pre and post- exercise at baseline and Week 12. Measurement of time to recovery of oxyhemglobin post-exercise at baseline and at Week 12., Blood draw
Device · Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mental Effort During Low Load Resistance Training in Older Adults

NCT07687316
View directory record Official record
Conditions
Seniors, Old Age, Sarcopenia
Interventions
Low Intensity Resistance Training with Maximal Mental Effort, Low Intensity Resistance Training
Behavioral
Lead sponsor
Kennesaw State University
Other
Eligibility
65 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Enrolling by invitation Not applicable Interventional

Blood Flow Restriction for Ulnar Sided Wrist Pain

NCT06963671
View directory record Official record
Conditions
Ulnar Wrist Pain
Interventions
Blood Flow Restriction
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Resistance Training and Cardiometabolic Health

NCT03325933
View directory record Official record
Conditions
Insulin Sensitivity, Endothelial Dysfunction, Blood Pressure
Interventions
High Load/Low Rep Resistance Training, Low Load/High Rep Resistance Training
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 8, 2026, 5:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women

NCT03888040
View directory record Official record
Conditions
Aging
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 8, 2026, 5:47 PM EDT
Terminated Not applicable Interventional

Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations

NCT04309227
View directory record Official record
Conditions
Rheumatoid Arthritis, Myositis, Osteoarthritis, Weakness, Muscle
Interventions
Strength Training
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional

CHAMP: A Randomized Controlled Trial of High-intensity Aerobic and Resistance Exercise for Metastatic Prostate Cancer

NCT02613273
View directory record Official record
Conditions
Prostate Cancer
Interventions
Experimental: Arm 1 (Aerobic Exercise), Experimental: Arm 2 (Resist. Exercise)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

NCT04255745
View directory record Official record
Conditions
Sarcopenia, High Blood Pressure, Hypertension
Interventions
progressive resistance training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Speed-specific Training and Ultrasound

NCT05513521
View directory record Official record
Conditions
High-Intensity Interval Training, Resistance Training
Interventions
High-velocity interval training, Resistance training
Other
Lead sponsor
University of Miami
Other
Eligibility
55 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 8, 2026, 5:47 PM EDT
Withdrawn Not applicable Interventional

BFRT vs Standard PT After Total Knee Arthroplasty

NCT04366336
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Blood Flow Restriction Training, Standard Physical Therapy
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
50 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional

BFRT for Severe Lower Extremity Muscle Atrophy

NCT04357184
View directory record Official record
Conditions
Severe Muscle Atrophy, Muscle Weakness
Interventions
Blood flow restriction training
Other
Lead sponsor
Cincinnati Sportsmedicine Research and Education Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Sep 8, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

NCT05586451
View directory record Official record
Conditions
Muscle, Acute Exercise
Interventions
Traditional High Load Resistance Exercise (HLRE), Low Load Resistance Exercise with Blood Flow Restriction (LLBFR), Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 8, 2026, 5:47 PM EDT
Recruiting Phase 4 Interventional

Bone, Exercise, Alendronate, and Caloric Restriction

NCT05764733
View directory record Official record
Conditions
Bone Loss
Interventions
Bisphosphonate, Resistance Training/Bone-Loading Exercise, Placebo
Drug · Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 8, 2026, 5:47 PM EDT