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ClinicalTrials.gov public records Last synced Nov 9, 2026, 9:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Low-Processed Food Diet Clear all

Conditions: Healthy Volunteers
Interventions: [11C] raclopride, liquid nutritive stimulus, Tasteless Oral Stimulus Solution, Minimally Processed Diet, Ultra Processed Diet, Baseline Diet; Drug · Other
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Diabetes Mellitus, Type 2
Interventions: Virta Health; Behavioral
Lead sponsor: Colorado Prevention Center; Other
Eligibility: 18 Years to 79 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Craig, Colorado • Lamar, Colorado • Salida, Colorado

Conditions: Fatty Liver
Interventions: Mod Fat/Low Processed Carb Diet and Moderate Exercise, Low Fat Diet and Moderate Exercise, Moderate Exercise Only; Behavioral
Lead sponsor: San Antonio Military Medical Center; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Type 2 Diabetes Mellitus in Obese
Interventions: NDPR diet, USDA healthy eating diet; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Non-Hodgkins Lymphoma, Sarcoma, Neuroblastoma
Interventions: Food Safety Guidelines, Neutropenic Diet; Other
Lead sponsor: Indiana University; Other
Eligibility: 1 Year to 30 Years
Enrollment: 149 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2017
U.S. locations: 6
States / cities: San Diego, California • Indianapolis, Indiana • Brooklyn, New York + 2 more

Conditions: Type2 Diabetes Mellitus, Hypertension, PreDiabetes, Overweight and Obesity
Interventions: DASH diet, Very low carbohydrate, ketogenic diet, Extras; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years to 70 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Healthy Diet, Obesity
Interventions: Ultra-processed food, high energy density (UPF HL), Ultra-processed food, both low (UPF LL), Ultra-processed food, both high (UPF HH), Unprocessed food diet (UNF LL); Other
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity
Interventions: Intervention Control, Counselling, Contrave, Contrave and Counseling; Behavioral · Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years to 65 Years
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Scottsbluff, Nebraska

Conditions: Type 2 Diabetes, Type 1 Diabetes, Pregnancy, High Risk
Interventions: Mid-Ohio Food Farmacy (MOF+) produce delivery, Nutrition education with Dining with Diabetes (DWD), Health Impact Ohio Central Ohio Pathways Hub to address unmet social needs; Dietary Supplement · Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Diabetes Mellitus, Type 2, PreDiabetes
Interventions: Mediterranean Diet (Med-Plus), Well-Formulated Ketogenic Diet (WFKD); Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Stanford, California

Conditions: Healthy Lifestyle
Interventions: Red meat-based meal, No meat diet; Other
Lead sponsor: South Dakota State University; Other
Eligibility: 65 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Brookings, South Dakota

Conditions: Pneumonia
Interventions: Ketogenic feeding, Standard feeding; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 55 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Diabetes Type 2, Diabetes Mellitus, Obesity
Interventions: Cryoablation of the Vagus Nerve, Lifestyle Intervention; Device · Behavioral
Lead sponsor: Emory University; Other
Eligibility: 22 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 5
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Obesity and Overweight
Interventions: Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 25 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity & Overweight, Cardiometabolic Risk Factors
Interventions: Mediterranean eating style, Physical activity, Mindful Eating, Body Appreciation, Enjoyable Exercise; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Breast Cancer
Interventions: Nutrition and resistance training exercise intervention; Other
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 20 Years to 89 Years · Female only
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cardiovascular Diseases, Type 2 Diabetes, Obesity and Obesity-related Medical Conditions
Interventions: Whole Food Plant Based Diet Jumpstart; Behavioral
Lead sponsor: Reya Andrews; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Diabete Type 2, Obesity & Overweight, Nutritional Intervention, Food Insecurity
Interventions: Meal kits, No-prep meals, Culinary nutrition classes, Text messages; Behavioral
Lead sponsor: Tufts University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Diet, Healthy, Diet Habit, Disease, Chronic, Health Behavior, Rural Health
Interventions: The UnProcessed Pantry Project (UP3); Behavioral
Lead sponsor: Montana State University; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Bozeman, Montana

Conditions: Cancer
Interventions: Mediterranean Diet; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Rochester, New York

Conditions: Blood Sugar; High, Blood Pressure, Dietary Habits
Interventions: Regular sweetened commercial foods, Allulose sweetened commercial foods, Whole and minimally processed and sweetened foods; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 20 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Irvine, California

Conditions: Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions: active surveillance, Sunphenon, laboratory biomarker analysis, Questionnaire Administration; Other · Drug
Lead sponsor: Sanjay Gupta PhD; Other
Eligibility: 45 Years to 85 Years · Male only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Ventral Hernia, Panniculus, Abdominoplasty, Flap Reconstruction
Interventions: Prehabilitation Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 19 Years and older
Enrollment: 520 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: San Jose, California • Stanford, California

Conditions: Obesity, Overweight
Interventions: Lifestyle Modification Intervention, Balanced Calorie Deficit Eating Plan, Ad Libitum Whole Food Plant-Based Eating Plan; Behavioral
Lead sponsor: Drexel University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

Effects of Ad Libitum Ultra-Processed Diet on Brain Dopamine in Humans

Virta Intervention in CommuniTies in cOloRado (VICTOR-Pilot)

Evaluation of Diet and Exercise in Patients With Non-Alcoholic Fatty Liver Disease

Effect of a Plant Rich Diet on in People With Type 2 Diabetes and Obesity

The Effectiveness of the Neutropenic Diet in Pediatric Oncology Patients

The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)

Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism

Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic

NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic Control and Pregnancy Outcomes With Pregestational Diabetes

Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial

Effect of Minimally Processed Animal Protein on Biomarkers for Cognitive Decline

Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial

Cryovagotomy Diabetes Trial

Effects of Ultra Processed Food on Intestinal Energy Harvest

Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight

EXERT-BCN: an Exercise and Nutrition Regimen to Designed to Improve Body Composition After Treatment for Breast Cancer

HEART Kitchen Pilot

Nutrition Intervention Optimization to Better Utilize Resources and Support Health

The UnProcessed Pantry Project (UP3)

The Effect of a Mediterranean Diet Intervention on Cancer-related Fatigue and Mitochondrial Function During Chemotherapy

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

Green Tea Extract in Treating Patients With Low-Risk Prostate Cancer

Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures

Remotely Delivered Behavioral Weight Loss Using an Ad Libitum Plant-Based Diet Versus a Balanced Calorie Deficit Diet