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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:39 AM EDT

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Showing 25–48 of 412 matching trials from the live ClinicalTrials.gov search.
Conditions
Obesity, Normal Physiology, Healthy Volunteers
Interventions
+200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, fasting, -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +200% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein, -25% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Active, not recruiting Not applicable Interventional

Early Intervention in Cognitive Aging

NCT02751866
Conditions
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Interventions
Berry fruit powder OR nutritional ketosis, Placebo powder OR higher carbohydrate
Dietary Supplement
Lead sponsor
University of Cincinnati
Other
Eligibility
50 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Active, not recruiting Not applicable Interventional

Functional Outcomes From Diets in Multiple Sclerosis

NCT05327322
Conditions
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Interventions
Glycemic load, Calorie restriction, Behavioral support
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Popular Diets Study

NCT00315354
Conditions
Obesity, Insulin Resistance
Interventions
Low glycemic index diet, Low fat diet, Very low carbohydrate diet
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Heart Failure
Interventions
Dietary Approaches to Stop Hypertension Diet
Other
Lead sponsor
University of Georgia
Other
Eligibility
65 Years to 110 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Early Phase 1 Interventional Accepts healthy volunteers

Satiety Response of Four Dietary Fibers

NCT01233024
Conditions
Healthy
Interventions
Control, Soluble corn fiber, Resistant starch, Fructooligosaccharide, Inulin
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Overweight, Obesity
Interventions
Low-carbohydrate Diet, Low-fat Diet
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Sarcoidosis
Interventions
Fluorodeoxyglucose, Rubidium, FDG-PET/CT with Rb82 Myocardial Perfusion Imaging
Drug · Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Suspended Not applicable Interventional Accepts healthy volunteers

The Effect of Nutritional Supplementation on Actinic Purpura: A Pilot Study

NCT06840574
Conditions
Skin Health, Skin Aging of Face and Hands, Healthy, Ecchymosis
Interventions
Cyruta Plus: A Whole-Food Based Vitamin C supplement containing organic buckwheat (aerial parts) juice powder, organic buckwheat flour, bovine adrenal Cytosol™ extract, oat flour, honey, ascorbic acid, Low Dose Vitamin C, High Dose Vitamin C
Dietary Supplement
Lead sponsor
Standard Process Inc.
Industry
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kannapolis, North Carolina
Conditions
Very Low Birth Weight Infants
Interventions
Lactoferrin
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
Up to 14 Days
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Charlottesville, Virginia
Conditions
Bariatric Surgery Candidate, Diet Modification
Interventions
Dietary modification with introduction of Mankai
Other
Lead sponsor
Cleveland Clinic Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Weston, Florida
Not listed Not applicable Interventional

Effect of Diet on Gulf War Illness

NCT02881944
Conditions
Irritable Bowel Syndrome
Interventions
Low FODMAP Diet, High FODMAP Diet
Behavioral
Lead sponsor
Ashok Tuteja
Federal
Eligibility
25 Years to 90 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Prostate Cancer
Interventions
Carbohydrate restricted diet, Non-restricted diet, Phone counseling with dietitian
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Imaging and Energy Balance Trial (DIET)

NCT00787280
Conditions
Obesity
Interventions
Low Carbohydrate Ketogenic Diet (LCKD), Low Fat Diet (LFD)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Type 2 Diabetes
Interventions
low-carbohydrate diet, low-fat diet
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Carbohydrate Availability and microRNA Expression

NCT03250234
Conditions
Glycogen Depletion
Interventions
Adequate Carbohydrate, Low Carbohydrate
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Natick, Massachusetts
Conditions
Cholesterol Metabolism, Ketone Metabolism
Interventions
Standard American diet, Very low carbohydrate diet
Other
Lead sponsor
Touro University, California
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Vallejo, California
Completed Not applicable Interventional Results available

Intermittent Fasting and a No-Sugar Diet for Long COVID Symptoms

NCT06214455
Conditions
Long Covid19, Long COVID
Interventions
Low sugar diet and 10-12 hour eating window, Low sugar diet, 8 hour eating window and fasting
Other
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
19 Years to 69 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Boulder, Colorado • Yakima, Washington
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Obesity, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver, Diet Modification
Interventions
Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate Diet, Dietary Intervention Standard Low Fat Diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
35 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Stanford, California
Completed Phase 3 Interventional Accepts healthy volunteers

Effects of the Atkins Diet Versus a Low Fat Diet on Inflammation

NCT00993278
Conditions
Cardiovascular Health, Obesity
Interventions
Low-Carbohydrate (Modified Atkins) Diet, Low-Fat (Heart Healthy) Diet
Dietary Supplement
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of High Carbohydrate vs. Low Carbohydrate Diet in Type 2 Diabetes

NCT04416204
Conditions
Diabetes Mellitus, Diabetes Mellitus, Type 2
Interventions
glycogen loading, No Glycogen Loading
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Role of Carbohydrate Modification in Weight Management Among Obese Children

NCT00215111
Conditions
Childhood Obesity
Interventions
Low carbohydrate, reduced glycemic load, and a control diet
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 12 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Overweight, Cardiovascular Diseases
Interventions
Low Fat and High Carbohydrate Diet, High Fat and Low Carbohydrate Diet
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Dietary Treatment Study of Pediatric NAFLD

NCT02513121
Conditions
Nonalcoholic Fatty Liver Disease
Interventions
Dietary modification
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
11 Years to 16 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
San Diego, California • Atlanta, Georgia