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ClinicalTrials.gov public records Last synced Sep 28, 2026, 9:23 AM EDT

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Showing 1–24 of 293 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Low-level laser therapy (LLLT) Clear all
Active, not recruiting Not applicable Interventional

A Clinical Study to Evaluate the Efficacy and Safety of Ultra in Promoting Hair Regrowth

NCT07588243
View directory record Official record
Conditions
Androgenic Alopecia
Interventions
Low Level Laser Therapy
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
22 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Glenview, Illinois • Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 28, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

Infrared Photobiomodulation in Humans With Epilepsy

NCT07145489
View directory record Official record
Conditions
Drug Resistant Epilepsy
Interventions
photobiomodulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Shockwave, Photobiomodulation, and Physical Therapy for Achilles Tendinopathy

NCT05751785
View directory record Official record
Conditions
Achilles Tendinopathy
Interventions
Physical Therapy, Shockwave Therapy, Photobiomodulation Therapy
Other · Device
Lead sponsor
Musculoskeletal Injury Rehabilitation Research for Operational Readiness
Federal
Eligibility
18 Years to 64 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Low Level Laser Therapy for Body Contouring

NCT00738426
View directory record Official record
Conditions
Body Contouring
Interventions
Erchonia ML Scanner (MLS), Sham device
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Palm Beach Gardens, Florida • Marion, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 9, 2020 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Phase 2Phase 3 Interventional Results available

A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

NCT00605280
View directory record Official record
Conditions
Macular Edema Associated With Diabetes Mellitus
Interventions
Standard of Care, Macugen
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
28
States / cities
Phoenix, Arizona • Tucson, Arizona • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

NCT00413868
View directory record Official record
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2008 · Synced Sep 28, 2026, 9:23 AM EDT
Terminated Not applicable Interventional

Evaluating Different Low-level Laser Therapies to Treat Neck Pain in Air Force Pilots and Flight Crew

NCT03945240
View directory record Official record
Conditions
Neck Pain
Interventions
Group 1 -- using Pinnacle Series Laser Device, Group 2 -- using Pinnacle Series Laser Device, Group 3 -- using Phoenix Thera-Lase Device
Procedure
Lead sponsor
Paul Crawford
Federal
Eligibility
18 Years to 62 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

NCT04018092
View directory record Official record
Conditions
Cognitive Aging, Alzheimer Disease, Protection Against
Interventions
Active NIR-PBM, Sham NIR-PBM
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Low-Level Laser Therapy for Plantar Fasciitis

NCT05763381
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Photobiomodulation Therapy (PBMT), Sham-Photobiomodualtion Therapy (Sham-PBMT)
Device
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 28, 2026, 9:23 AM EDT
Not listed Phase 1Phase 2 Interventional

Electrical Acupuncture and Laser Therapy for Low Back Pain

NCT00779818
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Electrical acupuncture, Laser
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Sep 28, 2026, 9:23 AM EDT
Not yet recruiting Phase 1 Interventional

Nanopulse Laser Therapy

NCT07520383
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Nano-Pulsed Laser Therapy (NPLT)
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 28, 2026, 9:23 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Laser Therapy Treatment of Peri-implantitis.

NCT01972399
View directory record Official record
Conditions
Peri-implantitis
Interventions
Laser, Mechanical debridement
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 2, 2015 · Synced Sep 28, 2026, 9:23 AM EDT
Not listed Early Phase 1 Interventional

Photobiomodulation to Improve Cognition in TBI, With fMRI

NCT04230577
View directory record Official record
Conditions
Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
Interventions
Real LED Intervention, Sham LED Intervention
Device
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Phase 1 Interventional

Identification and Treatment of Feeder Vessels in Macular Degeneration

NCT00018070
View directory record Official record
Conditions
Macular Degeneration
Interventions
Angiography, Laser Treatment
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Phase 3 Interventional Results available

RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity

NCT02375971
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Ranibizumab, Laser therapy
Drug · Procedure
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
Loma Linda, California • Sacramento, California • Aurora, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Approach to Treating Androgenetic Alopecia in Females With Low Level Laser Therapy

NCT01967277
View directory record Official record
Conditions
Androgenetic Alopecia
Interventions
Handi-Dome Laser, Incandescent red light source.
Device
Lead sponsor
Capillus, LLC
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Great Neck, New York • Woodbury, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Phase 4 Interventional

Correlation of MR Thermal Imaging to Actual Size of Ablation During Laser Ablation Therapy

NCT00688038
View directory record Official record
Conditions
Advanced Cancer, Bone Metastases
Interventions
Laser Ablation, Magnetic Resonance Thermal Imaging
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Sep 28, 2026, 9:23 AM EDT
Terminated Not applicable Interventional Results available

PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Lumpectomy

NCT00960154
View directory record Official record
Conditions
Breast Cancer
Interventions
PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
Device · Procedure
Lead sponsor
Medtronic Surgical Technologies
Industry
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2013 · Synced Sep 28, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

NCT07095556
View directory record Official record
Conditions
Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions
Low-level laser therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)

NCT02959307
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Transcranial Light Therapy, Sham Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Sep 28, 2026, 9:23 AM EDT
Withdrawn Not applicable Interventional

Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery

NCT00422045
View directory record Official record
Conditions
Surgery
Interventions
Low Level Laser Therapy
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

NCT02198131
View directory record Official record
Conditions
Oral Complications of Radiation Therapy, Stage I Laryngeal Cancer, Stage II Laryngeal Cancer
Interventions
laser therapy, questionnaire administration
Procedure · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 28, 2026, 9:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction

NCT00986453
View directory record Official record
Conditions
Macromastia
Interventions
PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
Device · Procedure
Lead sponsor
Medtronic Surgical Technologies
Industry
Eligibility
20 Years to 60 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
7
States / cities
Burbank, California • Glendale, California • Mountain View, California + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 31, 2012 · Synced Sep 28, 2026, 9:23 AM EDT
Terminated Phase 2 Interventional Results available

Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery

NCT01220739
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Transcranial Laser Therapy
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Englewood, Colorado • Columbia, South Carolina • Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2016 · Synced Sep 28, 2026, 9:23 AM EDT