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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.

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Filters: Intervention: Lumbar Drain Clear all

Conditions: Subarachnoid Hemorrhage
Interventions: Normal Saline, Nicardipine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 214 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Park Ridge, Illinois

Conditions: Severe Traumatic Brain Injury, Intracranial Hypertension
Interventions: External Lumbar drainage; Procedure
Lead sponsor: Brain Trauma Foundation; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 6
States / cities: Gainesville, Florida • Kansas City, Kansas • Dallas, Texas + 3 more

Conditions: Vasospasm, Intracranial, Subarachnoid Hemorrhage
Interventions: Extraventricular Drain, Lumbar Drain; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 110 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Glioblastoma, Malignant Glioma, Recurrent Glioblastoma, Recurrent Malignant Glioma
Interventions: Biospecimen Collection, Computed Tomography, Dexamethasone, Invasive Procedure, Magnetic Resonance Imaging, RAGE Antagonist FPS-ZM1, Resection; Procedure · Drug
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Duarte, California

Conditions: Parkinson Disease
Interventions: Sham Manipulation; Other
Lead sponsor: University of North Texas Health Science Center; Other
Eligibility: 50 Years and older
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Spinal Cord Injury
Interventions: CSFD and elevation of MAP, Maintenance of MAP; Procedure
Lead sponsor: St. Joseph's Hospital and Medical Center, Phoenix; Other
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 3
States / cities: Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona

Conditions: Normal Pressure Hydrocephalus
Interventions: Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy; Device · Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Orange, California

Conditions: Headache Disorders, Headache, Analgesia, Opioid Use, Osteopathy
Interventions: Osteopathic Manipulative Treatment (OMT), Sham Light touch arm; Other
Lead sponsor: New York Institute of Technology; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Old Westbury, New York

Conditions: Lumbar Fusion
Interventions: Postoperative Drain Placement, No Postoperative Drain Placement; Other
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Lumbar Spinal Stenosis, Thoracic Spinal Stenosis
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: NPH (Normal Pressure Hydrocephalus)
Interventions: Intellidrop Automated CSF Drainage System; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 60 Years to 99 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Chronic Knee Pain
Interventions: Photobiomodulation therapy (PBM) device, Sham PBM device; Device
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Complications, Postoperative
Interventions: Drain; Device
Lead sponsor: Twin Cities Spine Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 975 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2040
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: HIV Positive
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 110 Years
Enrollment: 1,150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2013
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Quality of Life
Interventions: Lumbar Drain; Device
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity, Lumbar Spine Surgery
Interventions: Closed-Incision Negative-Pressure Therapy; Device
Lead sponsor: Norton Leatherman Spine Center; Other
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Louisville, Kentucky

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Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage

External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial

Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage

FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma

Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease

Cerebrospinal Fluid Drainage (CSFD) in Acute Spinal Cord Injury

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders?

Wound Drain After Lumbar Fusion Surgery

Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery

Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

A Prospective, Randomized Comparison Of Drainage Techniques After One- Or Two-Level Open Posterior Lumbar Decompression Or Decompression And Fusion

Thinking and Memory Problems in People With HIV

Lumbar Drain After Endoscopic Surgery of the Skull Base

WoundVac in Obese Patients Undergoing Lumbar Surgery