- Conditions
- Degenerative Disc Disease (DDD)
- Interventions
- Lumbar Interbody Fusion Devices
- Device
- Lead sponsor
- Spine and Scoliosis Research Associates
- Other
- Eligibility
- 18 Years to 110 Years
- Enrollment
- 465 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- San Francisco, California • New York, New York • Charlotte, North Carolina + 1 more
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Showing 1–24
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- Conditions
- Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
- Combination Product
- Lead sponsor
- Seton Healthcare Family
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Lumbar Disease
- Interventions
- Pedicle Screw
- Device
- Lead sponsor
- H Francis Farhadi, MD, PhD
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Scoliosis, Back Pain
- Interventions
- InterFuse
- Device
- Lead sponsor
- Vertebral Technologies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Syracuse, New York
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PureGen Osteoprogenitor Cell Allograft
- Biological
- Lead sponsor
- Alphatec Spine, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2011
- U.S. locations
- 3
- States / cities
- Beverly Hills, California • Middleton, Connecticut • Greensboro, North Carolina
- Conditions
- Degeneration of Lumbar Intervertebral Disc
- Interventions
- Aspen Spinous Process Fixation Device, Pedicle Screws
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 3
- States / cities
- Paducah, Kentucky • Lockport, New York • Medford, Oregon
- Conditions
- Degenerative Disc Disease
- Interventions
- HEALOS and Leopard Cage, Leopard Cage and Autograft
- Device
- Lead sponsor
- Advanced Technologies and Regenerative Medicine, LLC (ATRM)
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 138 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2006
- U.S. locations
- 17
- States / cities
- Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more
- Conditions
- Muscle Weakness, Pain, Postoperative, Paresthesia, Pain, Muscle
- Interventions
- Depo-Medrol, Gel-Flow NT
- Drug
- Lead sponsor
- Hardeep Singh
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Lumbar Spondylolisthesis, Lumbar Spine Degeneration
- Interventions
- Not listed
- Lead sponsor
- Methodist Health System
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 3,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Degenerative Disc Disease, Scoliosis
- Interventions
- Oblique Lateral Interbody Fusion
- Procedure
- Lead sponsor
- Medtronic Spinal and Biologics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 6
- States / cities
- Murrieta, California • San Francisco, California • Melbourne, Florida + 3 more
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- Trinica Anterior Lumbar Plate System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 3
- States / cities
- Daphne, Alabama • Mobile, Alabama • San Bernardino, California
- Conditions
- Degenerative Disc Disease
- Interventions
- TLIF with a PEEK Spacer System and XIA Spinal System
- Device
- Lead sponsor
- Olympus Biotech Corporation
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 10
- States / cities
- Los Angeles, California • San Diego, California • Durango, Colorado + 7 more
- Conditions
- Degenerative Disc Disease
- Interventions
- CALIBER
- Device
- Lead sponsor
- Globus Medical Inc
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 2
- States / cities
- Miami Beach, Florida • Charlotte, North Carolina
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- nanOss Bioactive - posterolateral gutter
- Device
- Lead sponsor
- Pioneer Surgical Technology, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 3
- States / cities
- La Jolla, California • San Francisco, California • Columbia, Missouri
- Conditions
- Pain, Stenosis, Spondylolisthesis
- Interventions
- Not listed
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 37 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Degenerative Disc Disease
- Interventions
- Novosis Putty, Standard of Care
- Device · Other
- Lead sponsor
- CGBio Inc.
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 316 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 10
- States / cities
- Little Rock, Arkansas • Sacramento, California • Miami, Florida + 7 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PDS System, Fusion
- Device
- Lead sponsor
- Interventional Spine, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio • Willow Grove, Pennsylvania
- Conditions
- Foraminal Stenosis, Degenerative Disc Disease, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
- Interventions
- CONDUIT™ Interbody Platform composed of the EIT (Emerging Implant Technologies) Cellular Titanium®
- Device
- Lead sponsor
- Farhan Karim
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Hartford, Connecticut
- Conditions
- Degenerative Disc Disease
- Interventions
- CHARITE
- Device
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- Not listed
- Enrollment
- 367 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 10
- States / cities
- Los Angeles, California • Golden, Colorado • Chicago, Illinois + 7 more
- Conditions
- Back Pain, Surgery-Complications, Narcotic Use, Physical Stress, Post Operative Pain
- Interventions
- Exparel, Bupivacain
- Drug
- Lead sponsor
- Foundation for Orthopaedic Research and Education
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Patients With Spinal Stenosis Indicated for MIS TLIF
- Interventions
- Erector spinae plane (ESP) block
- Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Biological · Procedure
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Jasper, Alabama
- Conditions
- Degenerative Disc Disease
- Interventions
- Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
- Drug · Diagnostic Test
- Lead sponsor
- Catherine R. Olinger
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Lumbar Disc Disease
- Interventions
- SIGNUS MOBIS PEEK Cage, SIGNUS MOBIS II ST Cage
- Device
- Lead sponsor
- Signus Medizintechnik GmbH
- Industry
- Eligibility
- 18 Years to 89 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- East Syracuse, New York