Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 23, 2026, 9:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Not listed Not applicable Interventional Accepts healthy volunteers

Lutein Supplementation in Healthy Children

NCT05314647
Conditions
Eye Fatigue, Diet, Healthy, Cognitive Change
Interventions
lutein, placebo
Dietary Supplement
Lead sponsor
Northcentral University
Other
Eligibility
8 Years to 16 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Des Moines, Iowa
Terminated Phase 1Phase 2 Interventional Results available

Macular Pigment and Visual Performance in Glaucoma Patients

NCT03959592
Conditions
Glaucoma
Interventions
Lutein, zeaxanthin and mesozeaxanthin, Placebo
Drug · Other
Lead sponsor
Felipe Medeiros, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Results available

The Zeaxanthin and Visual Function Study

NCT00564902
Conditions
Age Related Macular Degeneration, Cognition Disorders
Interventions
3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
Drug · Dietary Supplement
Lead sponsor
Chrysantis, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
North Chicago, Illinois
Conditions
Macular Degenerative Disease
Interventions
Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation
Other
Lead sponsor
Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
Interventions
Lumega-Z, Dorzolamide Hcl 2% Oph Soln, Placebo
Dietary Supplement · Drug · Other
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Completed Phase 3 Interventional Accepts healthy volunteers

Lutein Absorption in Healthy Adults

NCT01730898
Conditions
Healthy Subjects
Interventions
Study product containing lutein
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Addison, Illinois
Conditions
Retinitis Pigmentosa
Interventions
Lutein (10 or 30 mg/day) capsules
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
Not listed
Timeline
2001 – 2002
U.S. locations
1
States / cities
Baltimore, Maryland
Not listed Not applicable Interventional Accepts healthy volunteers

Pistachios and Neural Macular Pigment

NCT05283941
Conditions
Macular Degeneration, Retinal Degeneration, Retinal Diseases, Eye Diseases
Interventions
Pistachio Group
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
40 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Goji vs. Fiber on Macular Degeneration

NCT06237127
Conditions
Age-Related Macular Degeneration
Interventions
Goji berry, Fiber
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Sacramento, California
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Daily Consumption of Eggs on Cognitive Function in the Elderly

NCT01621646
Conditions
Mild Cognitive Impairment
Interventions
eggs or egg whites
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Lutein and the Retinopathy of Prematurity

NCT00672230
Conditions
Lactation
Interventions
Lutein supplement
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Recruiting Not applicable Interventional Accepts healthy volunteers

Synergistic Activity of Human Milk Nutrients and Infant Cognition

NCT03838536
Conditions
Breastfeeding, Exclusive
Interventions
Whole Egg Powder, Egg White Powder
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
3 Months to 35 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Kannapolis, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults

NCT01620567
Conditions
Mild Cognitive Impairment
Interventions
avocado, potato or chickpea
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Retinopathy of Prematurity
Interventions
carotenoids
Dietary Supplement
Lead sponsor
University of Utah
Other
Eligibility
Up to 21 Days
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers Results available

Macular Pigment and Glare Disability

NCT00909090
Conditions
Vision, Entoptic
Interventions
12 mg Lutein + Zeaxanthin, Visually identical placebo
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 40 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Age-related Macular Degeneration (AMD)
Interventions
Lutein-enriched-egg beverage (NWT-02), Placebo
Dietary Supplement
Lead sponsor
Newtricious R&D BV
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

NCT03769779
Conditions
Aging, Wrinkle, Skin Elasticity, Healthy, Hydration
Interventions
FloraGLO Lutein, Safflower Oil
Dietary Supplement
Lead sponsor
Kemin Foods LC
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Port Chester, New York
Conditions
Healthy
Interventions
Postnatal Dietary Supplement, Control Supplement
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Skin Health
Interventions
Beauty From Within, Placebo, Facial cleansing
Dietary Supplement · Other
Lead sponsor
Pharmanex
Industry
Eligibility
40 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
High Point, North Carolina
Terminated Not applicable Interventional Accepts healthy volunteers

2021 PMT iAge® Intervention Trial by Edifice Health

NCT04983017
Conditions
Chronic Inflammation, Inflammaging
Interventions
Dietary supplement, Placebo
Dietary Supplement · Other
Lead sponsor
Edifice Health
Industry
Eligibility
18 Years and older
Enrollment
781 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Greenbrae, California • Suwanee, Georgia
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Yellow Potatoes and Carotenoids

NCT07606001
Conditions
Carotenoids
Interventions
Yellow-flesh potatoes, White-flesh potatoes
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Alzheimer's Disease
Interventions
lutein/zeaxanthin, placebo
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
55 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a Zeaxanthin Intervention on Visuomotor Function

NCT02017418
Conditions
Behavior and Behavior Mechanisms
Interventions
zeaxanthin, combinatory supplement
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 40 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Non-proliferative Diabetic Retinopathy
Interventions
multi-component nutritional supplement capsules, multi-component dietary supplement
Dietary Supplement
Lead sponsor
ZeaVision, LLC
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Tacoma, Washington