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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 48 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: MMSE Clear all
Completed No phase listed Observational

Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease

NCT04688554
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Pain, Intractable, Depression
Interventions
fMRI and DTI, Behavioral questionnaires, Disease-Specific Patient-Reported Outcomes, Behavioral tests
Diagnostic Test · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Vibro-tactile Stimulation Intensity on Head Posture in Cervical Dystonia

NCT07245615
View directory record Official record
Conditions
Cervical Dystonia
Interventions
cervical vibrotactile stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pilot Testing a New Computer-based Screening Tool to Detect Cognitive Impairment

NCT01220674
View directory record Official record
Conditions
Cognitive Impairment
Interventions
cognitive testing
Other
Lead sponsor
University of Nebraska
Other
Eligibility
55 Years to 75 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting No phase listed Observational

Cognitive Impact of Neoadjuvant Chemotherapy for Gynecologic Cancers

NCT07125209
View directory record Official record
Conditions
Ovarian Cancer, Cognitive Change
Interventions
Patient Reported Outcomes Assessment, Cognitive and General Health Assessments
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans

NCT02765672
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Interventions
Driving Behavior Interview, Clinical Driving Assessment, Propensity for Angry Driving Scale, Community Integration Questionnaire, Satisfaction with Life, Fitness-to-Drive Screening Measure (FTDS), Simulated Driving Evaluation, Driving Safety Education, Occupational Therapy Driving Intervention (OT-DI), On-road driving test, Driving triggers evaluation
Behavioral · Other · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Terminated Not applicable Interventional Results available

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NCT00613886
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 27, 2026, 1:08 PM EDT
Terminated No phase listed Observational

Risk Factors for Complications After Carotid Endarterectomy

NCT03788980
View directory record Official record
Conditions
Postoperative Complications, Postoperative Cognitive Dysfunction
Interventions
Carotid endarterectomy, Mini Mental Status Examination
Procedure · Diagnostic Test
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Phase 3 Interventional

Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer

NCT00006349
View directory record Official record
Conditions
Cognitive/Functional Effects, Delirium, Depression, Lung Cancer, Radiation Toxicity
Interventions
vitamin E, donepezil hydrochloride, placebo
Dietary Supplement · Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
15
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Peoria, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Glaucoma Cause Loss of Brain Function?

NCT01303939
View directory record Official record
Conditions
Glaucoma
Interventions
magnetic resonance imaging (MRI) of the brain
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Probing Cortical Excitability and Cognitive Function With TMS

NCT03652012
View directory record Official record
Conditions
Cognitive Dysfunction
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neuropsychological Testing Using Mobile Devices

NCT01776086
View directory record Official record
Conditions
Inpatients With Normal Neurological Function
Interventions
Neurological testing
Behavioral
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detecting an MCI and Amyloid Digital Neuro Signature(DNS) Using Altoida's Multimodal Digital Biomarkers.

NCT06223438
View directory record Official record
Conditions
Alzheimer Disease, MCI
Interventions
Not listed
Lead sponsor
Altoida
Industry
Eligibility
50 Years and older
Enrollment
614 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

A Preliminary Study of 18F-AV-45 in Alzheimer's Disease and Healthy Elderly Volunteers

NCT01565291
View directory record Official record
Conditions
Alzheimer Disease
Interventions
florbetapir F 18
Drug
Lead sponsor
Avid Radiopharmaceuticals
Industry
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Baltimore, Maryland • North East, Maryland • Long Branch, New Jersey
Source: ClinicalTrials.gov public record
Updated May 18, 2012 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia

NCT01199913
View directory record Official record
Conditions
1. Postoperative Cognitive Dysfunction
Interventions
The intervention will be Mini-Mental Status Examination (MMSE)
Other
Lead sponsor
Loma Linda University
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping

NCT04928976
View directory record Official record
Conditions
Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes), Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)

NCT02230605
View directory record Official record
Conditions
Delirium
Interventions
Mini-Mental State Examination, Self-Administered Gerocognitive Examination, Geriatric Depression Scale, Charlson Comorbidity Index, Short Form 36 Health Survey, Confusion Assessment Method, Memorial Delirium Assessment Scale, Postoperative Quality of Recovery Scale
Other
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 27, 2026, 1:08 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - PAST Extension

NCT04937959
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer's Disease (Incl Subtypes), Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Mild Cognitive Impairment, Normal Cognition
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer

NCT00769951
View directory record Official record
Conditions
Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition, Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions
medical chart review, questionnaire administration, cognitive assessment, psychosocial assessment and care, quality-of-life assessment
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of DCTclock™ as a Cognitive Assessment Aid

NCT03238001
View directory record Official record
Conditions
Cognitive Function
Interventions
DCTclock
Device
Lead sponsor
Digital Cognition Technologies
Industry
Eligibility
55 Years to 95 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Maitland, Florida
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
View directory record Official record
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evolution of Memory Related Activity

NCT00902499
View directory record Official record
Conditions
Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2010 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

Spoken Discourse Biomarker of PD Cognitive Impairment

NCT05909163
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 90 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury

NCT04706208
View directory record Official record
Conditions
Spinal Cord Injuries, Neuropathic Pain
Interventions
Cognitive Multisensory Therapy, Usual Care, Clinical Assessment, Magnetic Resonance Imaging (MRI), OPTIONAL: blood draw
Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls

NCT01348061
View directory record Official record
Conditions
Alzheimer Disease, Progressive Supranuclear Palsy
Interventions
Not listed
Lead sponsor
KineMed
Industry
Eligibility
50 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
3
States / cities
Glendale, California • Eatontown, New Jersey • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2014 · Synced Oct 27, 2026, 1:08 PM EDT