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ClinicalTrials.gov public records Last synced Oct 29, 2026, 10:25 AM EDT

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Showing 49–72 of 261 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: MONOVISC Clear all
Completed Phase 4 Interventional Results available

A Treatment for Severe Inflammatory Acne Subjects

NCT02899000
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Adapalene 0.3% / benzoyl peroxide 2.5% emulsion gel, Oral doxycycline hyclate
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
12 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2022 · Synced Oct 29, 2026, 10:25 AM EDT
Recruiting Phase 4 Interventional

A Study of Revaree Plus in People With Breast Cancer

NCT07042581
View directory record Official record
Conditions
Breast Cancer, Stage 0 Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer, Stage 0 Breast Carcinoma, Stage II Breast Carcinoma, Stage III Breast Carcinoma, Hormone-receptor-positive Breast Cancer, Hormone Receptor Positive Breast Carcinoma, Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions
Revaree Plus
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 29, 2026, 10:25 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Battlefield Acupuncture With Sodium Hyaluronate Injections

NCT03456011
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Battlefield Acupuncture
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2018 · Synced Oct 29, 2026, 10:25 AM EDT
Terminated Not applicable Interventional Results available

Post-op Treatment With Hyaluronic Acid Injections

NCT01256788
View directory record Official record
Conditions
Meniscus Tear, Chondropathy/Degenerative Joint Disease (DJD)
Interventions
Euflexxa, Saline
Device · Other
Lead sponsor
The Hawkins Foundation
Other
Eligibility
40 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 29, 2026, 10:25 AM EDT
Terminated Phase 3 Interventional Results available

The MONOVISC Hip Osteoarthritis Study

NCT02698865
View directory record Official record
Conditions
Osteoarthritis of the Hip
Interventions
MONOVISC, Saline
Device
Lead sponsor
DePuy Mitek
Industry
Eligibility
30 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
27
States / cities
Tucson, Arizona • Encinitas, California • Rancho Mirage, California + 21 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis

NCT02674399
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
JointStem, Synvisc-One
Drug
Lead sponsor
Nature Cell Co. Ltd.
Industry
Eligibility
22 Years to 60 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Santa Monica, California • Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 29, 2026, 10:25 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC)

NCT02753595
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Eribulin mesylate, Biologic: PEGylated recombinant human hyaluronidase (PEGPH20), Biologic: PEGylated recombinant human hyaluronidase
Drug · Other
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Whittier, California • Atlanta, Georgia • Newnan, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 3 Interventional Results available

ORTHOVISC Shoulder Osteoarthritis Study

NCT00436969
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Orthovisc, Control
Device · Drug
Lead sponsor
DePuy Mitek
Industry
Eligibility
25 Years to 75 Years
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
13
States / cities
Encinitas, California • Fresno, California • Coral Gables, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers

NCT05622851
View directory record Official record
Conditions
Volume Deficiency of the Midface
Interventions
Restylane Contour, Juvederm Voluma
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Santa Rosa Beach, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions

NCT03241862
View directory record Official record
Conditions
Lip Rejuvenation
Interventions
Restylane® Silk
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 29, 2026, 10:25 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Restylane Silk Microinjections to Cheeks

NCT03742479
View directory record Official record
Conditions
Wrinkle
Interventions
Restylane® Silk
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 4 Interventional Results available

To Look at the Characteristics of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection

NCT01895959
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Euflexxa, Magnetic Resonance Imaging (MRI)
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand

NCT02650921
View directory record Official record
Conditions
Volume Deficit in the Hand
Interventions
Restylane Lyft with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
7
States / cities
Vista, California • Boulder, Colorado • Englewood, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 29, 2026, 10:25 AM EDT
Not listed Not applicable Interventional

Safety and Effectiveness Study of a Non-Crosslinked HA Alkylamide HYADD(TM) 4 Hydrogel for Osteoarthritis of the Knee

NCT02187549
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
HYMOVIS, Placebo
Device
Lead sponsor
Fidia Farmaceutici s.p.a.
Industry
Eligibility
40 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
21
States / cities
Birmingham, Alabama • Brimingham, Alabama • Phoenix, Arizona + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

Non-Inferiority Study Comparing 3 Weekly Injections of SUPARTZ® vs 3 Weekly Injections of Euflexxa® for Knee OA

NCT02110238
View directory record Official record
Conditions
Osteoarthritis
Interventions
Supartz, Euflexxa
Device
Lead sponsor
Bioventus LLC
Industry
Eligibility
40 Years to 80 Years
Enrollment
421 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds

NCT03319719
View directory record Official record
Conditions
Correction of Moderate to Severe Nasolabial Folds
Interventions
Belotero® Balance with integral lidocaine, Belotero® Balance
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Nashville, Tennessee • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50

NCT04192630
View directory record Official record
Conditions
Cataract
Interventions
CVisc50 OVD, ProVisc OVD, Cataract Surgery
Device · Procedure
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
45 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
22
States / cities
Chandler, Arizona • Phoenix, Arizona • Fayetteville, Arkansas + 18 more
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 29, 2026, 10:25 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Knee Brace When Combined With Viscosupplementation in the Treatment of Knee Osteoarthritis

NCT01478386
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Orthovisc, DonJoy HA lite knee brace, Orthovisc injections and DonJoy HA lite knee brace
Other · Device
Lead sponsor
OAD Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Warrenville, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2013 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation

NCT07849556
View directory record Official record
Conditions
Skin Aging, Facial Rhytides, Skin Tone
Interventions
AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
Other · Device
Lead sponsor
Cellese Inc.
Industry
Eligibility
30 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 2 Interventional Results available

Investigation of H01 in Adults With Pulmonary Hypertension Including Interstitial Lung Disease (The SATURN Study).

NCT05128929
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Hymecromone (H01), Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

An Open Label Trial for Treating Carpometacarpal Osteoarthritis of the Thumb: Pilot Study

NCT00198029
View directory record Official record
Conditions
Carpometacarpal Osteoarthritis
Interventions
Synvisc (hylan G-F20)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Targeting the Endothelial Glycocalyx to Enhance Vascular Function and Exercise-Induced Vascular Adaptations in Type 2 Diabetes

NCT05205005
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Endocalyx, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2025 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Not applicable Interventional

2 Weekly Intra-articular Hyaluronan Knee Injections, Given 1 wk. Apart, of HYMOVIS Combined With Physical Exercise Program (PEP) Compared to PEP Alone, in Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA)

NCT03281837
View directory record Official record
Conditions
Osteoarthritis, Knee, Knee Osteoarthritis, Patellofemoral Osteoarthritis
Interventions
HYMOVIS plus Physical Exercise Program (PEP), Physical Exercise Program (PEP) alone
Device · Other
Lead sponsor
Fidia Pharma USA Inc.
Industry
Eligibility
21 Years to 60 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
10
States / cities
Tucson, Arizona • Encinitas, California • Los Angeles, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 29, 2026, 10:25 AM EDT
Completed Phase 1 Interventional

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

NCT04262336
View directory record Official record
Conditions
Ototoxicity
Interventions
DB-020, Placebo
Drug
Lead sponsor
Decibel Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
4
States / cities
Miami, Florida • Kansas City, Kansas • Lake Success, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 29, 2026, 10:25 AM EDT