Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 12, 2026, 7:35 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 57 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: MR Guided Focused Ultrasound Clear all

Conditions: Obsessive-Compulsive Disorder
Interventions: ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 25 Years to 64 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 2
States / cities: Palo Alto, California • Boston, Massachusetts

Conditions: Epilepsy
Interventions: Neuro Ablation - Functional; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 4
States / cities: Stanford, California • Kansas City, Kansas • Rochester, Minnesota + 1 more

Conditions: Pancreatic Adenocarcinoma
Interventions: ExAblate 2100; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Uterine Fibroids
Interventions: MR Guided Focused Ultrasound, Placebo MR Guided Focused Ultrasound; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Breast Cancer
Interventions: high-intensity focused ultrasound ablation; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Benign Centrally-Located Intracranial Tumors
Interventions: ExAblate 4000 System; Device
Lead sponsor: InSightec; Industry
Eligibility: 5 Years to 22 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Miami, Florida • Houston, Texas

Conditions: Prostate Cancer
Interventions: TULSA-PRO; Device
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Trigeminal Neuropathic Pain
Interventions: Transcranial ExAblate, Sham Transcranial ExAblate, Crossover Transcranial Exablate; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Lumbar Facet Joint Pain
Interventions: ExAblate 2100; Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Stanford, California

Conditions: Breast Fibroadenoma
Interventions: ExAblate 2000; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 4
States / cities: Boca Raton, Florida • Boston, Massachusetts • Voorhees Township, New Jersey + 1 more

Conditions: Solid Tumors, Soft Tissue Sarcoma, Ewing Sarcoma, Malignant Epithelial Neoplasm, Rhabdomyosarcoma, Wilms Tumor, Hepatic Tumor, Germ Cell Tumor, Bone Metastases
Interventions: Magnetic Resonance-Guided High Intensity Focused Ultrasound, Lyso-thermosensitive Liposomal Doxorubicin; Device · Drug
Lead sponsor: Children's National Research Institute; Other
Eligibility: 12 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Leiomyoma
Interventions: ExAblate 2000; Device
Lead sponsor: InSightec; Industry
Eligibility: Female only
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Essential Tremor
Interventions: ExAblate Transcranial MRgFUS System; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: High Grade Glioma
Interventions: SONALA-001(ALA) and MR-Guided Focused Ultrasound device (MRgFUS), MR-Guided Focused Ultrasound device (MRgFUS); Combination Product · Device
Lead sponsor: Nader Sanai; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Uterine Fibroids
Interventions: ExAblate 2000; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 6
States / cities: Los Angeles, California • Boca Raton, Florida • Boston, Massachusetts + 3 more

Conditions: Progressive Glioblastoma, Recurrent Glioblastoma
Interventions: Aminolevulinic Acid Intravenous Formulation SONALA-001, Biospecimen Collection, Computed Tomography, Electronic Health Record Review, Magnetic Resonance Imaging, MRI-Guided Focused Ultrasound Ablation, Oral Aminolevulinic Acid Hydrochloride; Drug · Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Osteoid Osteoma
Interventions: MR-HIFU; Device
Lead sponsor: Children's National Research Institute; Other
Eligibility: Up to 25 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Trigeminal Neuralgia
Interventions: ExAblate Transcranial treatment; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 21 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Uterine Fibroids
Interventions: MR-HIFU treatment, Sham treatment; Device
Lead sponsor: Philips Healthcare; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 7
States / cities: Chicago, Illinois • Ann Arbor, Michigan • The Bronx, New York + 4 more

Conditions: Uterine Fibroids, Uterine Leiomyomas
Interventions: ExAblate 2000; Device
Lead sponsor: InSightec; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 4
States / cities: La Jolla, California • Burlington, Massachusetts • Kalamazoo, Michigan + 1 more

Conditions: Recurrent GBM
Interventions: SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS); Combination Product
Lead sponsor: SonALAsense, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 6
States / cities: Phoenix, Arizona • San Francisco, California • Rochester, Minnesota + 3 more

Conditions: Health Status Unknown, Elevated PSA
Interventions: Biopsy of Prostate, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, MRI Ultrasound Fusion Guided Biopsy; Procedure · Other · Diagnostic Test
Lead sponsor: University of Southern California; Other
Eligibility: 40 Years and older · Male only
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 4
States / cities: Los Angeles, California • Baltimore, Maryland • Detroit, Michigan + 1 more

Conditions: Essential Tremor
Interventions: MR-guided Focused Ultrasound Ablation; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 22 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Prostate Cancer
Interventions: Exablate Prostate Treatment; Device
Lead sponsor: InSightec; Industry
Eligibility: 50 Years and older · Male only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 5
States / cities: Stanford, California • Delray Beach, Florida • Boston, Massachusetts + 2 more

Search by objective public record fields.

Sonication-based OCD Neurosurgical Intervention Via Capsulotomy

MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001)

Magnetic Resonance Guided High Intensity Focused Ultrasound in Advanced Pancreatic Adenocarcinoma Treatment

Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids

MRI-Guided Ultrasound Energy in Treating Patients With Stage I, Stage II, or Stage IIIA Breast Cancer

A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects

Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer

Feasibility Study of ExAblate Thalamotomy for Treatment of Chronic Trigeminal Neuropathic Pain

MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain

MR Guided Focused Ultrasound Surgery in the Treatment of Breast Fibroadenomas

A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids

ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids

Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma

Safety and Feasibility of MR-Guided High Intensity Focused Ultrasound (MR-HIFU) Ablation of Osteoid Osteoma in Children

MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia

Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation

A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM

Diagnosing Clinically Significant Prostate Cancer In African American and White Men With Elevated PSA

3-D Tractography FUS Ablation for Essential Tremor

Continued Access of Focal MR-Guided Focused Ultrasound for Localized Intermediate Risk Prostate Lesions