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Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mailed FIT Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates

NCT05115916
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
Interventions
MyChart Priming Message
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
51 Years to 75 Years
Enrollment
3,880 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Parks & Pediatrics Fit Together

NCT05455190
View directory record Official record
Conditions
Pediatric Obesity, Implementation
Interventions
Fit Together, Educational materials
Behavioral
Lead sponsor
Duke University
Other
Eligibility
5 Years to 12 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Charlotte, North Carolina • Durham, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Letters Promoting Colorectal Cancer Testing

NCT04548765
View directory record Official record
Conditions
Cancer Colorectal
Interventions
Letter, Loss Frame and Fear Appeals, Transparency, Default Effect and Presentation of Alternatives, Enhanced Fear Appeals and Decoy Effect
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
14,644 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Comparative Effectiveness of FIT, Colonoscopy, & Usual Care Screening Strategies

NCT01710215
View directory record Official record
Conditions
Colorectal Cancer
Interventions
FIT Screening Strategy, Colon Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 64 Years
Enrollment
5,999 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Colorectal Cancer Death Through Mailed Outreach Screening

NCT02584998
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mailed-FIT, Screening invitation-reminder
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 74 Years
Enrollment
782 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Phase 3 Interventional

ColoRectal Cancer Screening for Southern California Community Health Centers

NCT04941300
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mailed FIT Outreach, Standardized navigation
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 75 Years
Enrollment
55,999 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 9, 2026, 6:43 PM EDT
Recruiting Not applicable Interventional

Fasting InTervention for Endometrial Cancer

NCT07622901
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Prolonged Overnight Fasting (POF), Blood Specimen Collection, Blood Sugar Monitor, Hysterectomy
Behavioral · Procedure · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions to Improve Colon Cancer Screening in Poor Rural Iowa Counties

NCT01477814
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Physician chart reminder, chart reminder, educational mat'ls, FIT, CR,ed mat'ls, FIT, phone call
Behavioral
Lead sponsor
Barcey T. Levy
Other
Eligibility
52 Years to 79 Years
Enrollment
743 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 23, 2017 · Synced Sep 9, 2026, 6:43 PM EDT
Recruiting Not applicable Interventional

Strategies for Optimizing a Mailed FIT Program in Appalachia

NCT07173985
View directory record Official record
Conditions
Colonic Neoplasms
Interventions
Standard FIT kit, Enhanced FIT kit, Telephone patient navigation, Text message patient navigation
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
45 Years to 74 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting

NCT04711473
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Colonoscopy Only, Choice, FIT Only
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 74 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pottstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Results available

Mailed FIT Outreach 2022

NCT05341622
View directory record Official record
Conditions
Colorectal Cancer, Colon Cancer
Interventions
Differentiated Box, Standard Mail, Text, No Text, Reminder, No Reminder
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 74 Years
Enrollment
5,460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Additional Mailed FIT Kits

NCT06805370
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Mailed Additional FIT Kit, Usual Care
Behavioral · Other
Lead sponsor
University of Southern California
Other
Eligibility
60 Years to 74 Years
Enrollment
1,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 9, 2026, 6:43 PM EDT
Enrolling by invitation Not applicable Interventional

Head to Head Trial of Mailed Cologuard to Mailed FIT

NCT06931860
View directory record Official record
Conditions
Colorectal Cancer Screening, Fecal Immunochemical Test, Multi-target Stool DNA, Colorectal Cancer (CRC)
Interventions
Cologuard, Fecal Immunochemical Test
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 49 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Awareness, Research, Education and Screening (CARES)

NCT01804179
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, Standard Intervention (SI) Educational Materials, CARES Intervention Educational Materials, Baseline Visit Survey, Follow-up Questionnaire
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
514 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Behavioral Science to Improve Colorectal Cancer Screening Rates With Mailed FIT Kits

NCT04746469
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Delayed automated phone call
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion

NCT03598166
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Septin9
Diagnostic Test
Lead sponsor
Peter S. Liang, MD MPH
Federal
Eligibility
50 Years to 75 Years
Enrollment
359 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Real-Time, Remote Monitoring System for Home-Based HIV Testing

NCT02876926
View directory record Official record
Conditions
HIV
Interventions
"Smart" home-based test for HIV, Home-based testing only, Reminder letters for clinic-based testing
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Health Literacy Interventions to Overcome Disparities in CRC Screening

NCT02360605
View directory record Official record
Conditions
Colorectal Cancer
Interventions
automated telephone reminder, prevention coordinator, Health literacy appropriate education and demonstration
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
50 Years to 75 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 9, 2026, 6:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The PRIME-CRC Trial to Promote CRC Screening in Rural Communities

NCT04313114
View directory record Official record
Conditions
Colorectal Cancer
Interventions
health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
45 Years to 75 Years
Enrollment
804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
Bastrop, Louisiana • Marion, Louisiana • Saint Joseph, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 9, 2026, 6:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Adherence to Minimally Invasive Testing

NCT02251782
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Epi proColon Test, Fecal Immunochemical Test (FIT)
Device
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
50 Years to 76 Years
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Portland, Oregon • Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Sep 9, 2026, 6:43 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Rural Indiana Screening for Colorectal Cancer

NCT06133439
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Colorectal Screen rates with implementation of evidence-based intervention
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
45 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Monroe, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 9, 2026, 6:43 PM EDT
Enrolling by invitation Not applicable Interventional

Colorectal Cancer Screening Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

NCT07636174
View directory record Official record
Conditions
Behavior, Health
Interventions
Post-visit patient messaging
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
3,888 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mailed FIT Outreach to Improve Colon Cancer Screening in the Safety-net System

NCT02613260
View directory record Official record
Conditions
Colonic Neoplasms
Interventions
FIT Outreach
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 75 Years
Enrollment
13,470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Sep 9, 2026, 6:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Assessing Repeat Fit Testing for CRC

NCT03248661
View directory record Official record
Conditions
Colo-rectal Cancer
Interventions
Now I'm Telling You
Behavioral
Lead sponsor
Richard Crosby
Other
Eligibility
30 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Sep 9, 2026, 6:43 PM EDT