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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mailed fecal immunochemical tests Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Letters Promoting Colorectal Cancer Testing

NCT04548765
View directory record Official record
Conditions
Cancer Colorectal
Interventions
Letter, Loss Frame and Fear Appeals, Transparency, Default Effect and Presentation of Alternatives, Enhanced Fear Appeals and Decoy Effect
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
14,644 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 24, 2026, 8:59 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam

NCT03013855
View directory record Official record
Conditions
Fecal Immunochemical Test
Interventions
FIT-SOC, FIT-DRE
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 24, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial

NCT06822530
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Educational Intervention, Electronic Health Record Review, Interview, Supportive Care, Survey Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
45 Years to 75 Years
Enrollment
682 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Flatbush FHC Proactive Colorectal Cancer Screening and Navigation

NCT05646355
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Proactive CRC Screening Outreach, Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 75 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 24, 2026, 8:59 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Proactive Outreach With FIT

NCT06269744
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Proactive Screening Outreach
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 75 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

Head to Head Pilot Trial of Mailed Cologuard to Mailed FIT

NCT06173375
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Cologuard, Fecal Immunochemical Test
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 49 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Health Literacy Interventions to Overcome Disparities in CRC Screening

NCT02360605
View directory record Official record
Conditions
Colorectal Cancer
Interventions
automated telephone reminder, prevention coordinator, Health literacy appropriate education and demonstration
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
50 Years to 75 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Increasing Colorectal Cancer (CRC) Screening Among Hispanic Primary Care Patients

NCT02272244
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Decision Support & Navigation, Standard
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
50 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
Allentown, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The PRIME-CRC Trial to Promote CRC Screening in Rural Communities

NCT04313114
View directory record Official record
Conditions
Colorectal Cancer
Interventions
health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
45 Years to 75 Years
Enrollment
804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
Bastrop, Louisiana • Marion, Louisiana • Saint Joseph, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Behavioral Science to Improve Colorectal Cancer Screening Rates With Mailed FIT Kits

NCT04746469
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Delayed automated phone call
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Addressing Colorectal Cancer in South Florida Firefighters

NCT05976282
View directory record Official record
Conditions
Colorectal Cancer, CRC
Interventions
Fecal Immunochemical Test, Septin9 Test
Other
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 65 Years
Enrollment
646 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Sep 24, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Bundled Cancer Screening and Genetic Services Navigation

NCT07228000
View directory record Official record
Conditions
Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
Interventions
Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral, Pretest education + usual care genetics referral
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
45 Years to 74 Years · Female only
Enrollment
820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Newark, Delaware • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation

NCT03181334
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Branch I, Branch II, Branch III, Branch IV, Branch V
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 74 Years
Enrollment
7,711 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC

NCT04890054
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Fecal Immunochemical Test, Interview, Patient Navigation
Other · Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
5,696 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Adherence to Minimally Invasive Testing

NCT02251782
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Epi proColon Test, Fecal Immunochemical Test (FIT)
Device
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
50 Years to 76 Years
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Portland, Oregon • Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates

NCT05115916
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
Interventions
MyChart Priming Message
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
51 Years to 75 Years
Enrollment
3,880 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 24, 2026, 8:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

mPATH-Cloud for Colorectal Cancer Screening

NCT06441487
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mobile Health Decision Support, Usual care
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
45 Years to 73 Years
Enrollment
1,062 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Awareness, Research, Education and Screening (CARES)

NCT01804179
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, Standard Intervention (SI) Educational Materials, CARES Intervention Educational Materials, Baseline Visit Survey, Follow-up Questionnaire
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
514 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Sep 24, 2026, 8:59 AM EDT
Enrolling by invitation Not applicable Interventional

Head to Head Trial of Mailed Cologuard to Mailed FIT

NCT06931860
View directory record Official record
Conditions
Colorectal Cancer Screening, Fecal Immunochemical Test, Multi-target Stool DNA, Colorectal Cancer (CRC)
Interventions
Cologuard, Fecal Immunochemical Test
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 49 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Colorectal Cancer Death Through Mailed Outreach Screening

NCT02584998
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mailed-FIT, Screening invitation-reminder
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 74 Years
Enrollment
782 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Latinos CARES (Colorectal Cancer Awareness, Research, Education and Screening)

NCT03078361
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Carcinoma
Interventions
Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, LATINOS CARES Toolkit, Standard Intervention
Other · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 70 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Additional Mailed FIT Kits

NCT06805370
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Mailed Additional FIT Kit, Usual Care
Behavioral · Other
Lead sponsor
University of Southern California
Other
Eligibility
60 Years to 74 Years
Enrollment
1,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Test Up Now Education Program

NCT04304001
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Community Health Advisor, Usual care
Behavioral
Lead sponsor
Florida A&M University
Other
Eligibility
45 Years to 64 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 24, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Geographically Clustered Mailing of Fecal Immunochemical Test (FIT) Kits

NCT03718221
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Usual Care FIT Screening Strategy, GeoMail FIT Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 64 Years
Enrollment
8,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 24, 2026, 8:59 AM EDT