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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:57 AM EDT

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Showing 433–456 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Completed No phase listed Observational

Effects of Physical Therapy on Isometric Neck Retraction Strength and Pain in Patients With Neck Disability

NCT04334655
View directory record Official record
Conditions
Neck Pain, Strength
Interventions
Physical Therapy
Other
Lead sponsor
Campbell University, Incorporated
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Firestone, Colorado • Cos Cob, Connecticut • Granby, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 22, 2026, 4:57 AM EDT
Not yet recruiting Not applicable Interventional

Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy

NCT07712458
View directory record Official record
Conditions
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Interventions
EMMA (Expert Manipulative Massage Automation)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Treatment of Acne Scarring With a Novel Procedure Combination

NCT00510055
View directory record Official record
Conditions
Acne Scarring
Interventions
subdermal manipulation ONLY, subdermal manipulation AND injection of a filler
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

EUS-Guided Rendezvous or Direct Interventions Versus Advanced ERCP Techniques for Biliary Access and Therapy

NCT01678326
View directory record Official record
Conditions
Disorders of Gallbladder, Disorders of Biliary Tract
Interventions
EUS-Rendezvous or direct intervention, Advanced ERCP Biliary Access Techniques
Procedure
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years and older
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02245425
View directory record Official record
Conditions
Neck Pain
Interventions
Supine Thoracic Spine Manipulation, Prone Thoracic Spine Manipulation
Other
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
22 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 9, 2018 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Effects Cervicothoracic Manipulation Versus Passive Upper Trapezius Stretch

NCT02552290
View directory record Official record
Conditions
Neck Pain
Interventions
Upper Trapezius Stretch, Cervicothoracic manipulation, No intervention
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 17, 2015 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents

NCT02111278
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham Manipulation, Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

NCT01318720
View directory record Official record
Conditions
Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Masefield and Cavallaro Physical Therapy
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 22, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional

Alcohol & Men's Sexual Risk Behaviors

NCT06158880
View directory record Official record
Conditions
Sexual Behavior, Alcohol Drinking, Sexual Aggression, Emotions
Interventions
Alcoholic Beverage, Non-alcoholic Beverage, Partner Negative Mood Manipulation, Partner Positive Mood Manipulation
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
21 Years to 30 Years · Male only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional Results available

The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion

NCT02691143
View directory record Official record
Conditions
Acute Non-complicated Postural Neck Pain
Interventions
TheraBand Kinesiology Tape
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 22, 2026, 4:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Interexaminer Reliability, Outcomes for Manipulation of Cervical Dysfunction, 3-D Kinematics

NCT01186718
View directory record Official record
Conditions
Human Cervical Motions
Interventions
Not listed
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 29, 2011 · Synced Oct 22, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Osteopathic Manipulative Treatment on Pelvic Floor Dysfunction, Activity, and Gait in Female Runners

NCT07812285
View directory record Official record
Conditions
Pelvic Floor Disfunction
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Elizabeth Perrero
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 22, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional

Role of Parent Interpretation Bias in the Transmission of Anxiety to Children

NCT05665491
View directory record Official record
Conditions
Anxiety
Interventions
HabitWorks, Self-Assessment
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
7 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

NCT03012425
View directory record Official record
Conditions
Insomnia, Related Distress Among Cancer Caregivers
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires, Diurnal Cortisol
Behavioral · Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
3
States / cities
Irvine, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Effect of OMT on Asthma Symptoms in Southwest Virginia

NCT00545376
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment - in clinic, Osteopathic Manipulative Treatment - at home, Education to physicians
Procedure · Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
5 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 22, 2026, 4:57 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Acute Effects of Stimulant Medication in College Students With ADHD

NCT03935646
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Stimulant Use, Working Memory, Change in Sustained Attention, Mood
Interventions
Adderall IR 10mg, Placebo
Drug
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 22, 2026, 4:57 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The Effect of Osteopathic Manipulative Techniques on Human Tear Composition

NCT07633496
View directory record Official record
Conditions
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions
Osteopathic Manipulative Treatment, Sham
Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reactivating Specific Memories During Sleep in Conjunction with a Suppression Context

NCT04702750
View directory record Official record
Conditions
Sleep, Consolidation
Interventions
Targeted memory reactivation (odors), Targeted memory reactivation (sounds)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 22, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional

HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches

NCT04609709
View directory record Official record
Conditions
Tension-Type Headache
Interventions
Thrust Manipulation, Electric Dry Needling and Exercise, Non-thrust Mobilization, Soft-Tissue Mobilization, Exercise and TENS
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia

NCT02420106
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Osteopathic Manipulative Medicine
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
2 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 22, 2026, 4:57 AM EDT
Not listed Not applicable Interventional

Prescriptive Mobilization Versus a Pragmatic Mobilization

NCT01940744
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Prescriptive Mobilization, Pragmatic Mobilization
Procedure
Lead sponsor
Walsh University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Des Moines, Iowa • North Canton, Ohio • Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Oct 22, 2026, 4:57 AM EDT
Not listed Not applicable Interventional

Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain

NCT02619500
View directory record Official record
Conditions
Neck Pain
Interventions
Home Exercise Program, Patient advice, encouragement, and education, Thrust Manipulation, Non-thrust Mobilizations
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2016 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Early Phase 1 Interventional

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

NCT03352232
View directory record Official record
Conditions
Stroke, Motor Dysfunction, Chronic Stroke, Ischemic Stroke
Interventions
HBOT and OMT
Combination Product
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Oct 22, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Postoperative Osteopathic Manipulative Treatment in Bariatric Surgery

NCT03833011
View directory record Official record
Conditions
Pain, Bariatric Surgery Candidate
Interventions
Osteopathic Manipulation
Procedure
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Oct 22, 2026, 4:57 AM EDT