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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:54 PM EDT

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Showing 529–552 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Completed No phase listed Observational

Asthma and Osteopathic Manipulative Treatment

NCT03864354
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

NCT01318720
View directory record Official record
Conditions
Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Masefield and Cavallaro Physical Therapy
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biomarkers of the Response to Osteopathic Manipulation

NCT00958646
View directory record Official record
Conditions
Healthy
Interventions
Osteopathic Manipulation, Placebo
Other
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Oct 22, 2026, 7:54 PM EDT
Not listed Not applicable Interventional

Effect of Lumbar Manipulation on Intervertebral Motion, Pain, and Disability

NCT06294132
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham Lumbar Manipulation
Procedure
Lead sponsor
Ithaca College
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional

Temporal Window and Episodic Future Thinking in CUD

NCT05507814
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Episodic Future Thinking (EFT), Control Episodic Thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional

Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis

NCT03167736
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
electric dry needling, manipulation, conventional physical therapy
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
50 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Canton, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Medicine to Reduce Developmental Delays

NCT04652063
View directory record Official record
Conditions
Extreme Prematurity, Neurodevelopmental Abnormality
Interventions
Osteopathic Manipulative Medicine
Other
Lead sponsor
University of Rochester
Other
Eligibility
1 Day to 14 Weeks
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 22, 2026, 7:54 PM EDT
Withdrawn Not applicable Interventional

Long Arm Vs Short Arm Fiberglass Cast for Treatment of Displaced Distal Radius Fractures

NCT03835065
View directory record Official record
Conditions
Distal Forearm Fractures
Interventions
Closed Reduction, Long Arm Fiberglass Cast, Short Arm Fiberglass Cast
Procedure · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
4 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 22, 2026, 7:54 PM EDT
Not listed No phase listed Observational

Understanding Experiences of People With Spinal Cord Injury Undergoing Activity-based Rehabilitation

NCT04000256
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Activity based rehabilitation
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Orange, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2023 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Balance Changes After Chiropractic Adjustments in Health Adults.

NCT03877367
View directory record Official record
Conditions
Postural Balance, Musculoskeletal Manipulation
Interventions
Upper extremity manipulation
Other
Lead sponsor
Parker University
Other
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 22, 2026, 7:54 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study

NCT06565065
View directory record Official record
Conditions
Healthy
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Light Touch, Exercise Protocol
Procedure · Other
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis

NCT05423509
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
Dynamic myofascial manipulation, Standard AIS treatment with observation or bracing
Other
Lead sponsor
University of New Mexico
Other
Eligibility
10 Years to 15 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Manipulation Effects on Abdominal Muscles

NCT01745939
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham manipulation
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmentation of Immune Response to COVID-19 mRNA Vaccination Through OMT With Lymphatic Pumps

NCT04928456
View directory record Official record
Conditions
Covid19
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability

NCT01438905
View directory record Official record
Conditions
Ankle Sprain
Interventions
Small amplitude (Grade IV) mobilization, High velocity, low amplitude (Grade V) mobilization
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 45 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Phase 2 Interventional Results available

Mitoxantrone, Etoposide, and Cytarabine (MEC) Plus Lenalidomide for Relapsed or Refractory Acute Myeloid Leukemia

NCT03118466
View directory record Official record
Conditions
AML
Interventions
Etoposide, Cytarabine, Lenalidomide, Mitoxantrone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 22, 2026, 7:54 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

MIST3: Active Patient Safety Reporting

NCT04161677
View directory record Official record
Conditions
Safety Issues
Interventions
Not listed
Lead sponsor
Parker University
Other
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 22, 2026, 7:54 PM EDT
Withdrawn Not applicable Interventional

Mastalgia Treatment: Is There a Role for Osteopathic Manipulative Treatment

NCT01643837
View directory record Official record
Conditions
Mastalgia
Interventions
Osteopathic Manipulative Treatment, Osteopathic Manipulative Light Touch Protocol (LT)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Oct 22, 2026, 7:54 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of an Office-based Limited Facelift and Hospital-based Full Facelift

NCT05419609
View directory record Official record
Conditions
Skin Aging, Facial Asymmetry, Aging Problems
Interventions
Limited facelift, Full facelift, FACE-Q | Aesthetics - Satisfaction With Lower Face and Jawline, FACE-Q | Aesthetics - Recovery Early Symptoms, FACE-Q | Aesthetics - Satisfaction with Outcome, FACE-Q | Aesthetics - Adverse Effects: Cheeks, Lower Face, Neck
Procedure · Other
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
40 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Oct 22, 2026, 7:54 PM EDT
Terminated Early Phase 1 Interventional

Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy

NCT00956904
View directory record Official record
Conditions
Prostate Cancer
Interventions
3-D TRUS navigation software during T-RALP
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years to 75 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 22, 2026, 7:54 PM EDT
Completed No phase listed Observational Results available

Spinal Manipulation Services vs. Prescription Drug Therapy for Long-term Care

NCT03669354
View directory record Official record
Conditions
Low Back Pain
Interventions
Not listed
Lead sponsor
Southern California University of Health Sciences
Other
Eligibility
64 Years to 84 Years
Enrollment
195 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Whittier, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional

OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department

NCT06987578
View directory record Official record
Conditions
Acute Pain
Interventions
OMT vs. Ibruprofen
Other
Lead sponsor
St. Joseph's Regional Medical Center, New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 22, 2026, 7:54 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peri-neural Electrical Dry Needling Migraine Treatment Study

NCT04252391
View directory record Official record
Conditions
Migraine Headache
Interventions
Perineural electrical dry needling, Standard Care
Procedure
Lead sponsor
Wheaton Franciscan Healthcare
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 22, 2026, 7:54 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia

NCT02420106
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Osteopathic Manipulative Medicine
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
2 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 22, 2026, 7:54 PM EDT