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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:19 AM EDT

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Showing 49–72 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Manipulation, Exercise, and Self-Care for Low Back Pain

NCT00269347
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Spinal Manipulation, Exercise, Self-care
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2005 · Synced Oct 20, 2026, 8:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Conversational Agent Vaccine Promotion RCT

NCT04884750
View directory record Official record
Conditions
Pandemics
Interventions
ECA-ACE Vaccination Promotion Intervention
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 20, 2026, 8:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Motion Capture and Analysis of NYIT Athletes

NCT02727049
View directory record Official record
Conditions
Athletic Injuries
Interventions
Osteopathic manipulative medicine (OMM)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VelaShape III Device in Comparison to Cryolipolysis for Circumferential Reduction

NCT02143960
View directory record Official record
Conditions
Abdominal Fat
Interventions
VelaShape III, CoolSculpt
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Metairie, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional

Combined Effects of Manual Therapy on the Shoulder

NCT04777370
View directory record Official record
Conditions
Range of Motion, Manual Therapies, Shoulder Joint Disorder
Interventions
posterior glide mobilization, Sleeper stretch, thoracic manipulation
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Phase 2 Interventional

Chiropractic Care, Medication, and Self-Care for Neck Pain

NCT00029770
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic spinal manipulation, Acetaminophen, Self-care, Non-Steroidal anti-inflammatory drugs (NSAIDS), Tylenol with codeine
Procedure · Drug · Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2008 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional Results available

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

NCT03083886
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care, Individualized Postural Therapy (IPT) + PCP led care, Usual PCP led care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
3,087 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
8
States / cities
Phoenix, Arizona • Laguna Hills, California • North Hollywood, California + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 20, 2026, 8:19 AM EDT
Not listed Not applicable Interventional

B Vitamin Supplementation to Chiropractic Management of Chronic LBP: Pilot Clinical Trial (VCLBP)

NCT06576739
View directory record Official record
Conditions
Recurrent Low Back Pain
Interventions
Spinal Manipulation
Procedure
Lead sponsor
University of Western States
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

NCT01188837
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Full Kinetic Chain Manipulative Therapy, Full Kinetic Chain Rehabilitation, Full Kinetic Chain Manipulative Therapy with Rehabilitation
Other
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
38 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2012 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional

Ultrasound Evaluation of OMT for Sacral Base Asymmetry

NCT02820701
View directory record Official record
Conditions
Manipulation, Osteopathic
Interventions
OMT
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
20 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 20, 2026, 8:19 AM EDT
Recruiting Not applicable Interventional

Seated Balance Using the Indego™

NCT04047992
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Indego™ Exoskeleton
Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 20, 2026, 8:19 AM EDT
Recruiting Not applicable Interventional

Perspectives on Spinal Manipulative Therapy for Low Back Pain

NCT06590116
View directory record Official record
Conditions
Low Back Pain
Interventions
Physical therapy, Physical therapist provider
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 20, 2026, 8:19 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip

NCT02844764
View directory record Official record
Conditions
Osteoarthritis
Interventions
[StroMed + platelet rich plasma (PRP)]
Biological
Lead sponsor
VivaTech International, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Grove City, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Ability of Osteopathic Structural Evaluation to Assess Gait

NCT04860999
View directory record Official record
Conditions
Osteopathic Manipulation, Postural; Defect, Somatic; Functional Disturbance
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 35 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 20, 2026, 8:19 AM EDT
Recruiting Not applicable Interventional

Decoding and Modulating Affective Brain States

NCT05437705
View directory record Official record
Conditions
Rumination, Major Depressive Disorder, Anxiety
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Phase 2 Interventional

Elderly Back Pain: Comparing Chiropractic to Medical Care

NCT00602901
View directory record Official record
Conditions
Subacute Low Back Pain, Chronic Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Usual medical care
Other · Drug
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
55 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis

NCT05423509
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
Dynamic myofascial manipulation, Standard AIS treatment with observation or bracing
Other
Lead sponsor
University of New Mexico
Other
Eligibility
10 Years to 15 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Phase 3 Interventional

Assessing Patient Response to Therapeutic Exercise Based on Clinical Prediction Rule (CPR) for Spinal Manipulation

NCT00916734
View directory record Official record
Conditions
Low Back Pain
Interventions
MDT (McKenzie Method), Spinal thrust manipulation
Procedure
Lead sponsor
Daemen College
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Amherst, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2011 · Synced Oct 20, 2026, 8:19 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Dynamic Connectivity Under Metabolic Constraints

NCT04840095
View directory record Official record
Conditions
Insulin Resistance, Healthy, Diet Modification, Aging
Interventions
Ketones, Glucose
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Charlestown, Massachusetts • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Oct 20, 2026, 8:19 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs

NCT04129437
View directory record Official record
Conditions
Low Back Pain
Interventions
Ibuprofen, Osteopathic manipulative treatment
Drug · Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 20, 2026, 8:19 AM EDT
Not yet recruiting Phase 4 Interventional

OMT for Adhesive Capsulitis

NCT07497737
View directory record Official record
Conditions
Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Interventions
Intra-articular Injection, Osteopathic Manipulative Therapy (OMT)
Drug · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Beachwood, Ohio • Westlake, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 8:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Mommio: Training in Vegetable Parenting

NCT02215421
View directory record Official record
Conditions
Obesity
Interventions
Mommio
Behavioral
Lead sponsor
Archimage, Inc.
Industry
Eligibility
18 Years to 45 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2016 · Synced Oct 20, 2026, 8:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Breathe: Slow Paced Breathing to Lower Blood Pressure

NCT00328016
View directory record Official record
Conditions
High Blood Pressure
Interventions
Guided Breathing, RESPeRATE
Behavioral · Device
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
40 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 8:19 AM EDT