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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:05 PM EDT

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Showing 193–216 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Completed Not applicable Interventional

iEAT 2.0 Open Trial

NCT03383029
View directory record Official record
Conditions
Gastrointestinal Disorders
Interventions
iEAT Program
Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Months to 6 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Structural Integration for Chronic Low Back Pain

NCT01322399
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Structural Integration, Usual care
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity

NCT00516984
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Sham, OMT
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 22, 2008 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Phantom Limb Pain

NCT02784548
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
Virtual Reality
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Parkinson Disease

NCT02107638
View directory record Official record
Conditions
Parkinson Disease
Interventions
OMM treatment arm, Counseling
Procedure · Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)

NCT00850447
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Remediation Therapy, Videogame
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

3-D Endoanal Ultrasound: Normative Anatomy of the Anal Sphincter in Nulliparous Females

NCT01123109
View directory record Official record
Conditions
Normal (no Known Injury) Anal Sphincter Female Anatomy
Interventions
3-D Endoanal Ultrasound
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Migraine Headaches

NCT04976985
View directory record Official record
Conditions
Chronic Migraine, Migraine Disorders, Headache Disorders, Headache, Migraine
Interventions
Osteopathic Manipulative Therapy (OMT), Standard of care
Procedure · Other
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations

NCT01582958
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Osteopathic Manipulative Treatment (OMT), sham omt
Procedure · Other
Lead sponsor
Michigan State University
Other
Eligibility
49 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 20, 2026, 10:05 PM EDT
Recruiting Not applicable Interventional

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

NCT06383091
View directory record Official record
Conditions
Total Thyroidectomy
Interventions
Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches, Scar massage, Voice Exercises, Placebo Anterior Neck Manual Therapy, Placebo Pain Neuroscience Education, Placebo Neck Stretches
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Recruiting Phase 2Phase 3 Interventional

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

NCT02314988
View directory record Official record
Conditions
Spinal Injuries, Spinal Deformity
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Anti-Snoring Appliances and Airway Manipulation in Patients Undergoing Anesthetic Sedation

NCT05748626
View directory record Official record
Conditions
Airway Obstruction, Snoring, Sedation Complication
Interventions
Anti-snoring device, No anti -snoring device during their procedure.
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Not applicable Interventional

Study Evaluating the Benefit of Dry Needling for Patients With Neck Pain

NCT01301170
View directory record Official record
Conditions
Neck Pain
Interventions
dry needling
Procedure
Lead sponsor
Integrated Therapy Practice PC
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Hobart, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 23, 2011 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Not applicable Interventional

Enhancement of Residual Limb Proprioception and Rehabilitation Training Methods With a Vibrotactile Device.

NCT02026570
View directory record Official record
Conditions
Transtibial Amputation
Interventions
Internal Focus of Attention, External Focus of Attention
Behavioral
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Manipulation of the Cervical Spine on Pain Biomarkers

NCT03176654
View directory record Official record
Conditions
Neck Pain, Posterior
Interventions
HVLAT manipulation, Sham HVLAT manipulation
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia

NCT06389266
View directory record Official record
Conditions
Schizophrenia, Nicotine Dependence
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Music Therapy for Persons With Dementia

NCT03643003
View directory record Official record
Conditions
Quality of Life, Social Interaction, Emotions, Mood, Feelings, Alzheimer Disease, Dementia
Interventions
Music therapy, Non-Music Verbal Interaction (Placebo)
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis

NCT04972929
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Spinal Manipulation, Sham Spinal Manipulation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sacroiliac Orthopedic Blocking and Cervical Spine Function

NCT00523822
View directory record Official record
Conditions
Musculoskeletal Diseases
Interventions
Spinal Manipulative Therapy
Other
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Recovery From Plantar Heel Pain Using the Fascial Distortion Model a Pilot Study

NCT04571073
View directory record Official record
Conditions
Plantar Fasciitis of Both Feet
Interventions
Fascial Distortion Model
Procedure
Lead sponsor
Eisenhower Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Gordon, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Oct 20, 2026, 10:05 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Study of Chitosan for Pharmacologic Manipulation of AGE Levels in Prostate Cancer Patients

NCT03712371
View directory record Official record
Conditions
Prostate Cancer
Interventions
Chitosan
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 20, 2026, 10:05 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Nursing Students' Brain/MS Immersive Three-Dimensional Learning Activity

NCT07538063
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
The immersive 360-degree educational video, The slideshow (PowerPoint) educational presentation
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Fairfield, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Temporal Window and Episodic Future Thinking in CUD

NCT05507814
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Episodic Future Thinking (EFT), Control Episodic Thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 20, 2026, 10:05 PM EDT