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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:26 AM EDT

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Showing 73–96 of 574 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manual Control Clear all
Completed Phase 4 Interventional

The Long-Term Quitting (Smoking Cessation) Study

NCT02564315
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Mini-Lozenge for 11 Months, Preparation Phase Behavioral Reduction Counseling, Preparation Phase Recycling Counseling, Preparation Phase Control Treatment, Cessation Phase Supportive Counseling, Cessation Phase Skill Training Counseling, Cessation Phase Brief Information, Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 21, 2026, 4:26 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention

NCT03950453
View directory record Official record
Conditions
Child Obesity
Interventions
Parenting Mindfully for Health Nutrition (PMH), Contact Control Nutrition (C+N), Non-randomized historical control (WLC) assessment only
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
2 Years to 5 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MAKO-Uni-Knee Arthroplasty Clinical Outcomes and Function

NCT03354195
View directory record Official record
Conditions
Clinical Outcomes
Interventions
Unicompartmental knee arthroplasty with the Mako Robotic Arm-assisted system.
Procedure
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
21 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Phase 2 Interventional

Brief Intervention for Problem Drinking and Partner Violence

NCT01207258
View directory record Official record
Conditions
Domestic Violence, Alcohol Abuse
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of the OPTIMAL Theory of Motor Learning With the Lower Quarter Y-Balance Test

NCT05113797
View directory record Official record
Conditions
Balance
Interventions
Lower Quarter Y-Balance Test, OPTIMAL motor learning theory
Diagnostic Test · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing Effects of Primal Reflex Release on the Body's Stress Response

NCT06305585
View directory record Official record
Conditions
Psychological Stress
Interventions
Primal Reflex Release Technique (PRRT)
Other
Lead sponsor
University of Idaho
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Phase 4 Interventional Results available

Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia

NCT02420015
View directory record Official record
Conditions
Schizophrenia, Cigarette Smoking
Interventions
Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling, Mobile Contingency Management, Stay Quit Coach, SMS text messaging
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 21, 2026, 4:26 AM EDT
Terminated Not applicable Interventional Results available

Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease

NCT03502447
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
TearCare, Warm Compress and Lid Massage
Device
Lead sponsor
Sight Sciences, Inc.
Industry
Eligibility
22 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
6
States / cities
Laguna Hills, California • Newport Beach, California • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 21, 2026, 4:26 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Maneuvers to Reduce Laparoscopic Pain

NCT07583433
View directory record Official record
Conditions
Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
Interventions
Smoke Evacuation Group, Recruitment Breath Group, Control Group
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Men Together Making a Difference: Health Promotion for Black Men

NCT02572414
View directory record Official record
Conditions
HIV, Cardiovascular Disease, Diabetes, Hypertension, Colon Cancer
Interventions
Health Promotion Intervention, Health Awareness Control Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years and older · Male only
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Integrative Risk Reduction and Treatment for Teen Substance Use Problems and PTSD

NCT01751035
View directory record Official record
Conditions
PTSD, Alcohol Use Disorders, Substance Use Disorders
Interventions
Risk Reduction through Family Therapy, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 18 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 21, 2026, 4:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stimulant Medication Effects on Auditory Sensitivity in Teens With ADHD

NCT04577417
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity
Interventions
ADHD stimulants, for example, amphetamine, dexmethylphenidate, dextroamphetamine, methylphenidate
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
13 Years to 19 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Use of Audio Recordings of Self-Hypnosis and Meditation for Fatigue Management in Multiple Sclerosis

NCT04688710
View directory record Official record
Conditions
Multiple Sclerosis, Fatigue
Interventions
Self-Hypnosis (HYP), Mindfulness Meditation (MM)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Effects of Mindfulness on PTSD

NCT03484390
View directory record Official record
Conditions
Mindfulness, Stress Disorder, Posttraumatic
Interventions
Mindfulness-based stress reduction, Wellness Group
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 21, 2026, 4:26 AM EDT
Not listed Not applicable Interventional

The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders

NCT06602375
View directory record Official record
Conditions
Temporomandibular Disorders (TMD)
Interventions
Standard care, Physical Therapy (PT)
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 21, 2026, 4:26 AM EDT
Suspended Phase 2Phase 3 Interventional

Ankle Manual Therapy for Ankle Sprains

NCT00888498
View directory record Official record
Conditions
Sprains and Strains
Interventions
Passive Positioning, High-Velocity, Low-Amplitude Stretch, Slow, Mobilization Stretch
Other
Lead sponsor
University of the Pacific
Other
Eligibility
16 Years to 60 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2015 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Interactive Multirisk-Factor Intervention for Hypertension (HTN) Blacks

NCT00207194
View directory record Official record
Conditions
Hypertension
Interventions
Automated Telephone Program, Health Behavior Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
35 Years and older
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Pain Modulatory Profiles in Massage for Individuals With Neck Pain

NCT03534739
View directory record Official record
Conditions
Musculoskeletal Pain, Neck Pain
Interventions
Pain Inducing Massage, Light Touch Massage, Coldpressor
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 21, 2026, 4:26 AM EDT
Recruiting Phase 2 Interventional

DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

NCT06749210
View directory record Official record
Conditions
Cancer of the Breast, Chemotherapy-induced Neuropathy
Interventions
Tango
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
40 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Comparing Dry Needling to Manual Therapy for Patients With Mechanical Low Back Pain

NCT02312895
View directory record Official record
Conditions
Low Back Pain
Interventions
Manual therapy, Dry needling, Home Exercise Program
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 21, 2026, 4:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multifocal HD-tDCS and Motor Function

NCT06561165
View directory record Official record
Conditions
Healthy
Interventions
Standard HD-tDCS intervention, Multifocal network targeted HD-tDCS intervention, Functional Magnetic Resonance Imaging (fMRI)
Device
Lead sponsor
University of Michigan
Other
Eligibility
65 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 4:26 AM EDT
Completed Phase 1Phase 2 Interventional

Duration of Spinal Manipulation Effects as Influenced by Orthotics

NCT01704807
View directory record Official record
Conditions
Low Back Pain
Interventions
foot orthotics, Sham foot orthotic
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Oct 21, 2026, 4:26 AM EDT
Terminated Not applicable Interventional Results available

The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)

NCT04957732
View directory record Official record
Conditions
Abscess
Interventions
Standard of Care (SoC), Irrisept Delivery System
Device
Lead sponsor
Irrimax Corporation
Industry
Eligibility
12 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 21, 2026, 4:26 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Motivational Interviewing to Increase Uptake of Drug Checking and Safe Drug Use Behaviors to Reduce Overdose

NCT06855836
View directory record Official record
Conditions
Overdose
Interventions
MI-CHANCE (TS + FTIR + MI), TS + FTIR + Flu and Hepatitis A Education
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 21, 2026, 4:26 AM EDT