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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 574 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manual Control Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Does the Addition of Manual Therapy Techniques Increase Gastrocnemius/Soleus Length More Than Stretching Alone?

NCT01856972
View directory record Official record
Conditions
Muscle Tightness
Interventions
Instrument Assisted Soft Tissue Mobilization, Rearfoot joint mobilization, Static stretching/ROM exercises
Procedure · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2014 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion

NCT02750566
View directory record Official record
Conditions
Post-Concussion Symptoms, Distorted; Balance
Interventions
Osteopathic Manipulative Treatment, Counseling
Procedure · Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Phase 2 Interventional

Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury

NCT00448045
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Manual and mechanical assisted cough, Incentive spirometry
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery

NCT06525701
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
Execise Group, Control Group
Other
Lead sponsor
Loyola University
Other
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Not listed Not applicable Interventional

Online-Delivered Comprehensive Behavioral Intervention for Tics-Enhanced (CBIT-E)

NCT05050734
View directory record Official record
Conditions
Persistent Tic Disorders, Tourette Disorder
Interventions
Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E)
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
9 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 8, 2021 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)

NCT03335657
View directory record Official record
Conditions
Lower Extremity Injury
Interventions
CBPT, Education Treatment
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
633 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
8
States / cities
Tampa, Florida • Indianapolis, Indiana • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety

NCT07717541
View directory record Official record
Conditions
Dyspepsia, Gastroparesis, Anxiety, Depression
Interventions
Poetry, Poetry Manual
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Kettlebell Training Measured Across Power and Performance

NCT02731625
View directory record Official record
Conditions
Athletic Performance, Weight Lifting
Interventions
Kettlebell training, Army Physical Readiness Training
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
17 Years to 27 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MAKO-Uni-Knee Arthroplasty Clinical Outcomes and Function

NCT03354195
View directory record Official record
Conditions
Clinical Outcomes
Interventions
Unicompartmental knee arthroplasty with the Mako Robotic Arm-assisted system.
Procedure
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
21 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 21, 2026, 5:22 PM EDT
Not listed Not applicable Interventional

The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders

NCT06602375
View directory record Official record
Conditions
Temporomandibular Disorders (TMD)
Interventions
Standard care, Physical Therapy (PT)
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptation and Initial Evaluation of Transdiagnostic CBT for Anxious and Depressed Smokers

NCT03920137
View directory record Official record
Conditions
Smoking Cessation
Interventions
UP-ST Therapy, Standard Therapy, Nicotine Patch
Behavioral · Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

NCT07187388
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS), Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions
Transcutaneous Electrical Nerve Stimulation to reduce facial pain and improve jaw range of motion in ALS and PLS
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults

NCT02044081
View directory record Official record
Conditions
Dental Caries
Interventions
C16G2 Rinse, Placebo, C16G2 Gel
Drug
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Kalispell, Montana • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 21, 2026, 5:22 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults

NCT03803566
View directory record Official record
Conditions
Aging
Interventions
Pegboard practice, Force control practice
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 89 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Effectiveness of Early Physical Therapy Intervention for Patients With Dizziness After a Sports-Related Concussion

NCT02299128
View directory record Official record
Conditions
Brain Concussion, Dizziness
Interventions
Physical Therapy Treatment
Other
Lead sponsor
Walsh University
Other
Eligibility
10 Years to 23 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
North Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Knee Flexionater to Avoid Motion Restoring Surgery

NCT07454356
View directory record Official record
Conditions
Joint Contractures, Total Knee Anthroplasty, Knee Arthrofibrosis
Interventions
Hydraulic high Intensity Stretch Device, Standard Physical Therapy
Device · Other
Lead sponsor
Ermi LLC
Industry
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Phase 4 Interventional

Study of the SafeSeal(TM) Hemostasis Patch Following Percutaneous Coronary Artery and Peripheral Vascular Interventions

NCT00481741
View directory record Official record
Conditions
Coronary Artery Disease, Peripheral Vascular Disease
Interventions
SafeSeal(TM) Hemostasis Patch
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2009 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linking Lives: Building Quality Parent Components for School-Based Health Programs in Middle Schools

NCT00136279
View directory record Official record
Conditions
Smoking, Sexual Behavior
Interventions
Linking Lives parent-based intervention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
Not listed
Enrollment
9,510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2009 · Synced Oct 21, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD

NCT03932773
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Active rTMS, Sham rTMS, Cognitive Processing Therapy
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
3
States / cities
Tallahassee, Florida • Addison, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Physical Rehabilitation Evaluation and Optimal Physical Therapy (PRE-OPT)

NCT04225572
View directory record Official record
Conditions
Breast Cancer
Interventions
Physical Therapy: Dependent on Patient's Needs
Behavioral
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Elements Vital to Treat Obesity Study

NCT04708769
View directory record Official record
Conditions
Obesity
Interventions
Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 5:22 PM EDT
Withdrawn Phase 2 Interventional

MAP4343 Treatment for Alcohol Use Disorder

NCT04157114
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
MAP4343, Placebo, Standardized behavioral counseling
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 21, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Financial Incentives to Promote Stimulant Abstinence in a Community-Based Syringe Exchange Program

NCT05787847
View directory record Official record
Conditions
Stimulant Use
Interventions
Incentives for Abstinence, Health Education
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 21, 2026, 5:22 PM EDT
Not listed Not applicable Interventional

Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel

NCT05147506
View directory record Official record
Conditions
Depressive Symptoms, Mild Traumatic Brain Injury
Interventions
CNRM DTx, Psychoeducation Comparison
Device · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Oct 21, 2026, 5:22 PM EDT