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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Completed No phase listed Observational Accepts healthy volunteers

A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

NCT05594004
Conditions
Gingivitis, Dental Plaque
Interventions
Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Gingivitis, Plaque
Interventions
manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Costa Mesa, California
Completed Not applicable Interventional Results available

Evaluating the Effect of Tooth Cleaning Devices on Oral Health

NCT01250769
Conditions
Dental Plaque
Interventions
Manual Toothbrush, Interproximal Cleaning Device
Device
Lead sponsor
Philips Oral Healthcare
Industry
Eligibility
18 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Dental Plaque Induced Gingivitis, Dental Plaque
Interventions
Oral B Healthy Clean Manual Toothbrush, BURST Sonic Oral Care, Philipps Sonicare DiamondClean 300 Series
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Plaque Induced Gingivitis
Interventions
Bixdo Ultra Compact Water Flosser, Manual toothbrush
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 70 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Inflammation, Periodontitis
Interventions
Sonicare/Elite-Flexcare Toothbrush, Manual Toothbrush
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Plaque and Gingivitis Evaluation of a U-Shaped Toothbrush in a 30-Day Model

NCT06122376
Conditions
Plaque Induced Gingivitis
Interventions
U-shaped Power Toothbrush, Soft Manual Toothbrush
Device
Lead sponsor
Lander Enterprises, LLC
Industry
Eligibility
5 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Gingivitis, Gingival Bleeding, Dental Plaque
Interventions
Device: Electric Flosser, Manual toothbrush
Device
Lead sponsor
Flaus, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Noblesville, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Self-selection Study of the Toothwave Toothbrush

NCT04023097
Conditions
Gingivitis, Plaque, Calculus, Tooth Discoloration
Interventions
Toothwave toothbrush
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Conditions
Gingivitis, Plaque
Interventions
Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,145 participants
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Plaque, Dental, Gingivitis
Interventions
Test regimen, Control regimen
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Melbourne, Florida
Conditions
Gingivitis, Gingival Bleeding, Dental Plaque
Interventions
Electric Flosser, Manual Toothbrush
Device
Lead sponsor
Flaus, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health

NCT02187016
Conditions
Gingivitis
Interventions
AirFloss + BreathRx, AirFloss + Listerine, Dental Floss, Manual Toothbrush
Device
Lead sponsor
Philips Oral Healthcare
Industry
Eligibility
18 Years to 65 Years
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
Gingivitis
Interventions
power toothbrush, manual toothbrush
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Health Adult Subjects
Interventions
Beaming White, Philips Zoom Professional Whitening Treatment, Opalescence Boost PF, Fluoride Toothpaste, Soft Manual Toothbrush, CP LED, Gingival Barrier
Drug · Combination Product · Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Melbourne, Florida
Completed Not applicable Interventional Accepts healthy volunteers

At-Home Care for Subjects With Periodontitis

NCT04254770
Conditions
Periodontitis, Dental Plaque
Interventions
ADA approved Manual Toothbrush, Marketed Power Toothbrush
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 75 Years
Enrollment
346 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Dentin Sensitivity
Interventions
Potassium Oxalate, Stannous fluoride paste, Manual toothbrush, Power toothbrush
Device · Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fresno, California
Conditions
ASD I, ASD2
Interventions
Hum by Colgate Smart Kids Toothbrush (battery powered) - 490000006871
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
5 Years to 12 Years
Enrollment
17 participants
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Interventional Accepts healthy volunteers Results available

Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use

NCT04899440
Conditions
Gingivitis, Plaque
Interventions
Water Flosser, Control
Device · Other
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Plaque Removal of a Novel Brushing Device

NCT05038293
Conditions
Dental Plaque
Interventions
Automated mouthpiece-based toothbrush, Manual toothbrush
Device
Lead sponsor
University of Washington
Other
Eligibility
5 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers Results available

Powertoothbrushing for Treating Gingivitis

NCT03381339
Conditions
Gingivitis
Interventions
Oscillating rotating power toothbrush
Device
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Dental Plaque, Gingivitis
Interventions
Mouthwash, Floss, Toothbrush, Toothpaste
Drug · Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Dental Caries
Interventions
C16G2 Rinse, Placebo, C16G2 Gel
Drug
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Kalispell, Montana • Salt Lake City, Utah
Conditions
Caries Risk, Caries, Dental
Interventions
Powered toothbrush
Device
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan