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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Manual compression Clear all
Completed Phase 3 Interventional

Evaluation of Fibrin Sealant 2 in Vascular Surgical Procedures

NCT00154141
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Fibrin sealant (FS2)
Drug
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
13
States / cities
Jacksonville, Florida • Miami, Florida • Springfield, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2006 · Synced Sep 9, 2026, 6:13 AM EDT
Recruiting Not applicable Interventional

Vascular Closure With a Device Compared to Manual Compression After Atrial Fibrillation Ablation: The LockeT II Study

NCT06078735
View directory record Official record
Conditions
Atrial Fibrillation, Hemostasis
Interventions
Vascular closure with LockeT device
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Not applicable Interventional

Complete Decongestive Therapy on Head and Neck Lymphedema

NCT04045860
View directory record Official record
Conditions
Lymphedema of Face, Secondary Lymphedema
Interventions
Complete Decongestive Therapy, Observation
Procedure · Other
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 7, 2021 · Synced Sep 9, 2026, 6:13 AM EDT
Recruiting No phase listed Observational

International Device Assisted Controlled Sequential Elevation CPR Registry

NCT05588024
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
Head Up CPR based bundle of care
Device
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 9, 2026, 6:13 AM EDT
Completed No phase listed Observational

Groin Complications Post Percutaneous Coronary Intervention Using Either Manual Compression or PERCLOSE Device

NCT00842179
View directory record Official record
Conditions
Vascular Closure
Interventions
Not listed
Lead sponsor
Clinyx, LLC
Other
Eligibility
18 Years and older
Enrollment
2,517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 11, 2009 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Not applicable Interventional Results available

RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

NCT01297322
View directory record Official record
Conditions
Surgical Wound
Interventions
Manual compression, Cardiva VASCADE™ Vascular Closure System
Other · Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 9, 2026, 6:13 AM EDT
Active, not recruiting Phase 1 Interventional

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

NCT05937269
View directory record Official record
Conditions
Lymphedema of Face, Head and Neck Cancer
Interventions
Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
Combination Product · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Not applicable Interventional Results available

Comparison of Percutaneous Closure to Manual Compression for Hemostasis

NCT04180540
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Percutaneous Closure, Manual Compression
Device · Other
Lead sponsor
Michael S. Lloyd
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Phase 3 Interventional Results available

The EVARREST® Fibrin Sealant Patch Liver Study

NCT01993888
View directory record Official record
Conditions
Hemorrhage
Interventions
EVARREST® Fibrin Sealant Patch, Standard of Care (SoC)
Biological · Other
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
10
States / cities
Birmingham, Alabama • Augusta, Georgia • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced Sep 9, 2026, 6:13 AM EDT
Terminated Not applicable Interventional Results available

The Effect of Irrisept for Irrigation of Skin and Soft Tissue Infections (Irrisept USF Study)

NCT01076049
View directory record Official record
Conditions
Skin and Soft Tissue Infections, Abscess
Interventions
Standard of Care (SoC), Irrisept Delivery System
Device
Lead sponsor
Irrimax Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Not applicable Interventional Results available

Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)

NCT01600482
View directory record Official record
Conditions
Cardiac Disease, Coronary Artery Disease
Interventions
CELT ACD
Device
Lead sponsor
Vasorum Ltd
Industry
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Camden, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Sep 9, 2026, 6:13 AM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease

NCT07165340
View directory record Official record
Conditions
Chronic Venous Disease
Interventions
Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound, compression wrap
Combination Product · Device · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 9, 2026, 6:13 AM EDT
Active, not recruiting Not applicable Interventional

Venous Sinus Stenting With the River Stent in IIH

NCT03556085
View directory record Official record
Conditions
Idiopathic Intracranial Hypertension
Interventions
Venous sinus stenting (Serenity River)
Device
Lead sponsor
Serenity Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
6
States / cities
Jacksonville, Florida • Buffalo, New York • Manhasset, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Phase 2 Interventional Results available

Fibrin Sealant Vascular Surgery Study

NCT00576420
View directory record Official record
Conditions
Adjunct to Hemostasis in Vascular Surgery (Synthetic Vascular Grafts)
Interventions
FS VH S/D 500 s-apr, 60-seconds polymerization time, FS VH S/D 500 s-apr, 120-seconds polymerization time, Manual compression with surgical gauze pads
Biological · Procedure
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
Not listed
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
11
States / cities
Birmingham, Alabama • Tucson, Arizona • Long Beach, California + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2012 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Heart and Hands Study II: A Retrospective Data Collection & Analysis Project

NCT02307318
View directory record Official record
Conditions
Thrombosis
Interventions
SoftSeal Hemostatic Pad
Device
Lead sponsor
HealthEast Care System
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 9, 2026, 6:13 AM EDT
Terminated Not applicable Interventional Results available

ARISTOCRAT-A Randomized Controlled Trial Evaluating Closure Following Access With the AXERA (Device Name) 2 Access System

NCT02061696
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Vascular Access Device, Standard Manual Compression
Device · Procedure
Lead sponsor
Frank Saltiel
Other
Eligibility
18 Years to 85 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Sep 9, 2026, 6:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients

NCT01089686
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Venoplasty, Sham procedure (non-treatment)
Procedure
Lead sponsor
Manish Mehta, MD
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2012 · Synced Sep 9, 2026, 6:13 AM EDT
Enrolling by invitation Not applicable Interventional

Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

NCT06837870
View directory record Official record
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 9, 2026, 6:13 AM EDT
Active, not recruiting Not applicable Interventional

Subclinical Lymphedema Treatment Study

NCT03292198
View directory record Official record
Conditions
Breast Cancer-related Subclinical Lymphedema
Interventions
20-30 mmHg compression sleeve and gauntlet, Manual Lymphatic Drainage
Other
Lead sponsor
Mercy Research
Other
Eligibility
18 Years and older · Female only
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 9, 2026, 6:13 AM EDT
Active, not recruiting No phase listed Observational

Imaging Sodium and Lymphatics in Lymphedema

NCT05242900
View directory record Official record
Conditions
Lymphedema of Leg, Lymphedema, Secondary, Lymphedema Related Fibrosis
Interventions
Complete decongestive therapy, Standard imaging protocol
Procedure · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Phase 3 Interventional Results available

Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device

NCT00345631
View directory record Official record
Conditions
Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis, Peripheral Arteriosclerosis
Interventions
Manual Compression, Vascular Closure Device
Other · Device
Lead sponsor
Cordis US Corp.
Industry
Eligibility
18 Years to 85 Years
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
17
States / cities
Phoenix, Arizona • Sacramento, California • Stanford, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Sep 9, 2026, 6:13 AM EDT
Completed Not applicable Interventional Results available

Circulation Improving Resuscitation Care (CIRC)

NCT00597207
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
AutoPulse, Manual
Device · Other
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
4,231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Tampa, Florida • Houston, Texas • Menasha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 9, 2026, 6:13 AM EDT
Recruiting Not applicable Interventional

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

NCT05890677
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Surgical Intervention, Conservative Complex Physical Decongestion Therapy
Procedure
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2036
U.S. locations
4
States / cities
New Haven, Connecticut • Boston, Massachusetts • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 9, 2026, 6:13 AM EDT
Not listed Not applicable Interventional

Lymphedema Treatment for Blunt Facial Trauma

NCT02977182
View directory record Official record
Conditions
Post-traumatic Facial Edema
Interventions
Complete Decongestive Therapy (CDT)
Other
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 29, 2016 · Synced Sep 9, 2026, 6:13 AM EDT