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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Manual stretching Clear all
Withdrawn Not applicable Interventional

Dry Needling for Patients With Back Pain

NCT03586778
View directory record Official record
Conditions
Back Pain
Interventions
dry needling, manual therapy, therapeutic exercise
Other
Lead sponsor
Concord Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 5, 2026, 9:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Quantitative Ultrasound Biomarkers to Assess Upper Trapezius Muscles in Patients With Chronic Pain

NCT05497622
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Quantitative Ultrasound, Osteopathic TART Assessment, Osteopathic Manipulation Treatment
Diagnostic Test · Procedure
Lead sponsor
Rocky Vista University, LLC
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ivins, Utah
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Dry Needling Versus Conventional Physical Therapy in Patients With Plantar Fasciitis

NCT02373618
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
DN and conventional PT, Conventional PT
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Sep 5, 2026, 9:09 PM EDT
Not listed Early Phase 1 Interventional

Clinical Assessment of Two Manipulative Protocols in Treatment of Hip Osteoarthritis

NCT00523172
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
manual or manipulative therapy, Manual / Manipulative Therapy, Supportive Care
Procedure
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
40 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2010 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does the Addition of Manual Therapy Techniques Increase Gastrocnemius/Soleus Length More Than Stretching Alone?

NCT01856972
View directory record Official record
Conditions
Muscle Tightness
Interventions
Instrument Assisted Soft Tissue Mobilization, Rearfoot joint mobilization, Static stretching/ROM exercises
Procedure · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2014 · Synced Sep 5, 2026, 9:09 PM EDT
Terminated Not applicable Interventional

Dynamic Splinting for Patients With Adhesive Capsulitis

NCT00873158
View directory record Official record
Conditions
Adhesive Capsulitis
Interventions
Dynasplint
Device
Lead sponsor
Dynasplint Systems, Inc.
Industry
Eligibility
40 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
3
States / cities
Solana Beach, California • Gulf Breeze, Florida • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 11, 2013 · Synced Sep 5, 2026, 9:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Physical Activity Participation in Latinas With Mindfulness

NCT06848335
View directory record Official record
Conditions
Inactivity, Inactivity/Low Levels of Exercise, Inactivity, Physical
Interventions
Remote Physical Activity Intervention, Mindfulness Enhanced Remote Physical Activity Intervention, Attention Matched Enhanced Remote PA intervention
Behavioral
Lead sponsor
Bess Marcus
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
258 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine

NCT03588364
View directory record Official record
Conditions
Migraine Disorders, Post-Traumatic Headache
Interventions
Osteopathic Manipulation
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional Results available

Physical Activity Interventions To Heal Chronic Low Back Pain

NCT04678297
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Physical activity + emotion regulation intervention, Physical activity control intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Storrs Mansfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Phase 2Phase 3 Interventional

Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial

NCT01571674
View directory record Official record
Conditions
Shoulder Pain
Interventions
Manipulation + Exercise Group, Exercise Group
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
9
States / cities
Aurora, Colorado • Boulder, Colorado • Concord, New Hampshire + 5 more
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Objective Kinematic Correlates of Palpatory Diagnosis

NCT00728247
View directory record Official record
Conditions
Cervical Spine
Interventions
Manual Therapy Techniques
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2010 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Combined Effects of Manual Therapy on the Shoulder

NCT04777370
View directory record Official record
Conditions
Range of Motion, Manual Therapies, Shoulder Joint Disorder
Interventions
posterior glide mobilization, Sleeper stretch, thoracic manipulation
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Phase 1 Interventional

Project FARMS: Fall Risk Reduction in Multiple Sclerosis

NCT01837017
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Home-based Exercise
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Sep 5, 2026, 9:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain

NCT04660708
View directory record Official record
Conditions
Pregnancy Related, Delivery; Injury, Maternal, Pelvic Floor Disorders
Interventions
manual physical therapy
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Hales Corners, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders

NCT03959319
View directory record Official record
Conditions
Hip-related Groin Pain, Femoroacetabular Impingement, Dysplasia Mild, Prearthritic Hip Disorder
Interventions
Movement Pattern Training, Manual Therapy
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Physical Activity in Multiple Sclerosis (MS): A Novel Approach to Study Outcomes

NCT02297932
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Strength training, Stretching
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional Results available

Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACT

NCT03677440
View directory record Official record
Conditions
Multiple Sclerosis, Cognitive Impairment
Interventions
Treadmill Walking Exercise Training, Stretching-and-Toning Exercise Training
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia

NCT03167710
View directory record Official record
Conditions
Lateral Epicondylitis
Interventions
Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 60 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cockeysville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms

NCT00690196
View directory record Official record
Conditions
Sleep Disorders, Sleep Initiation and Maintenance Disorders, Dyssomnias, Mental Disorders, Nervous System Diseases
Interventions
Tai Chi Chih, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
30 Years to 70 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adapted Lifestyle-integrated Functional Exercise Program for Medically Underserved Older Adults

NCT03704194
View directory record Official record
Conditions
Accidental Fall
Interventions
Adapted LiFE, Attention control
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
70 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Effect of Gluten-Free Dietary Education and Intraneural Facilitation® Therapy on Quality of Life in People With Diabetic Neuropathy

NCT05165368
View directory record Official record
Conditions
Diabetic Neuropathy, Distal Symmetric Polyneuropathy (Manifestation)
Interventions
Intraneural Facilitation® Therapy (INF® Therapy), INF® Therapy
Other
Lead sponsor
Loma Linda University
Other
Eligibility
50 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 5, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Translational Manipulation Under Interscalene Block for Adhesive Capsulitis of the Shoulder (TMACS)

NCT03090555
View directory record Official record
Conditions
Shoulder Adhesive Capsulitis, Frozen Shoulder, Adhesive Capsulitis of Shoulder
Interventions
Translational manipulation, Manual therapy
Procedure
Lead sponsor
Daniel G. Rendeiro
Federal
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Sep 5, 2026, 9:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Craniosacral Therapy for Concussion Symptoms

NCT04820192
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Craniosacral Therapy
Other
Lead sponsor
Special Therapies, Inc.
Other
Eligibility
14 Years to 90 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Sep 5, 2026, 9:09 PM EDT
Not yet recruiting Not applicable Interventional

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786
View directory record Official record
Conditions
Spine, Low Back Pain, Neck Pain
Interventions
Massage, Talk-based therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 5, 2026, 9:09 PM EDT