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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Marijuana Clear all
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

NCT02404688
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active delta-9-THC, Placebo, Active Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis

NCT05664763
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
[18F]FPEB with PET, Cannabis abstinence
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

SV2A in Older Adults

NCT05465538
View directory record Official record
Conditions
Cannabis Use
Interventions
[11C]UCB-J PET
Drug
Lead sponsor
Yale University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Suspended Phase 2 Interventional

Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment

NCT05427630
View directory record Official record
Conditions
Migraine, Cannabis, THC
Interventions
THC ~2.5%, THC ~5%, THC ~10%, Sham Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 2 Interventional Results available

Buspirone, Stress, and Attentional Bias to Marijuana Cues

NCT02132832
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Buspirone, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Neural Correlates of Cannabis Use

NCT03104257
View directory record Official record
Conditions
Cannabis Dependence, Healthy
Interventions
[11-C]OMAR
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Short-Term Exposure for PTSD

NCT02874898
View directory record Official record
Conditions
Chronic Post-Traumatic Stress Disorder, Marijuana Abuse
Interventions
Brief Imaginal Exposure
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Cannabis' Impact on Alcohol Consumption

NCT05389930
View directory record Official record
Conditions
Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
Interventions
THC-dominant cannabis, CBD-dominant cannabis, Cannabis placebo, Alcohol, Alcohol placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years to 50 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alcohol and Cannabis Co-Use and the Gut-Brain Axis

NCT04998006
View directory record Official record
Conditions
Cannabis Use, Alcohol Use, Inflammation
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 60 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Not listed No phase listed Observational

Evaluating the Effects of Cannabis Use and Circulating Cannabinoids on Tumor Infiltrating Lymphocytes in Malignant Melanoma

NCT05520294
View directory record Official record
Conditions
Melanoma
Interventions
High-performance liquid chromatography-tandem mass spectrometry assays
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 100 Years
Enrollment
90 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Trial of Contingency Management for Long-Term Cannabis Abstinence

NCT03786224
View directory record Official record
Conditions
Cannabis Use, Adolescent Behavior
Interventions
Contingency Management
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 19 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational

MEMO-Medical Marijuana and Opioids Study

NCT03268551
View directory record Official record
Conditions
Opioid Use, Marijuana, Chronic Pain, HIV/AIDS
Interventions
Not listed
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
The Bronx, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 3, 2026, 6:06 AM EDT
Not listed No phase listed Observational

EEG Monitoring in the Emergency Department

NCT04070521
View directory record Official record
Conditions
Drug Overdose, Substance Abuse, Alcohol Abuse
Interventions
Observational EEG Monitoring
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Tetrahydrocannabinol (THC) and Sleep

NCT03560934
View directory record Official record
Conditions
Sleep, THC, Marijuana, Cannabis
Interventions
Dronabinol
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 34 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

NCT05052541
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
THC/CBD, THC, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 84 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Individual Differences in Drug Response

NCT03809546
View directory record Official record
Conditions
Differential Female Response to Δ9-tetrahydrocannabinol (THC)
Interventions
Dronabinol, dextrose
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Cannabis Versus Oxycodone for Pain Relief

NCT02892591
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
Cannabis, Oxycodone, Placebo for Cannabis, Placebo for Oxycodone
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Comparative Pharmacokinetic and Pharmacodynamic Effects of Delta-8 and Delta-9 THC

NCT05287256
View directory record Official record
Conditions
Behavioral Pharmacology of Cannabis
Interventions
Oral Delta-8-THC Cannabis, Oral Delta-9-THC Cannabis, Oral Placebo, Vaporized Delta-8-THC Cannabis, Vaporized Delta-9-THC Cannabis, Vaporized Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy

NCT02191605
View directory record Official record
Conditions
Marijuana Use, Pregnancy
Interventions
eSBIRT, Tailored texting
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Sep 3, 2026, 6:06 AM EDT
Terminated Early Phase 1 Interventional Results available

Lorcaserin for Cannabis Use Disorder

NCT03637842
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Lorcaserin, Placebo oral capsule
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Influencer E-Cigarette and Cannabis Marketing: a Survey-Based Experiment Among Adolescents

NCT06919263
View directory record Official record
Conditions
Electronic Nicotine Delivery Systems
Interventions
Influencer marketing
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
16 Years to 17 Years
Enrollment
1,462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Yeahhh Baby! Ointment on Hip and/or Knee Pain in Men and Women

NCT04764552
View directory record Official record
Conditions
Joint Pain
Interventions
Yeahhh Baby Ointment, Coconut oil ointment
Dietary Supplement · Other
Lead sponsor
University of Memphis
Other
Eligibility
35 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

Medical Cannabis and Behavior

NCT06808048
View directory record Official record
Conditions
Chronic Pain Patients, Medical Cannabis Users
Interventions
Cognitive testing, Task-based fMRI measure of face-name and verbal learning
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Nabilone in Cannabis Users With PTSD

NCT03251326
View directory record Official record
Conditions
Cannabis, Post Traumatic Stress Disorder
Interventions
Nabilone, Cannabis, Propranolol, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2022 · Synced Sep 3, 2026, 6:06 AM EDT