Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Long-Term Evaluation of Approved and Investigational Contact Lenses

NCT02625233
Conditions
Visual Disorders
Interventions
senofilcon C, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
6
States / cities
Jacksonville, Florida • Longwood, Florida • Bloomington, Illinois + 3 more
Conditions
Myopia
Interventions
SofLens Daily Disposable, Marketed 1 Day Contact Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Rochester, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Corneal Barrier Function With Multi-Purpose Solutions

NCT00407238
Conditions
Contact Lens Care
Interventions
Multi-purpose solutions (polyquaternium-1 and PHMB)
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Fullerton, California
Conditions
Refractive Error
Interventions
senofilcon C, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Bloomington, Illinois + 7 more
Completed Not applicable Interventional Results available

Safety and Efficacy of a Contact Lens for Daily Disposable Use

NCT01365039
Conditions
Myopia
Interventions
Test, daily disposable contact lens, SofLens daily disposable contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 40 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved and Investigational Contact Lenses Using New UV Additive

NCT02982018
Conditions
Visual Acuity
Interventions
senofilcon A with new UV blocker, senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Jacksonville, Florida • Longwood, Florida • Sarasota, Florida + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of 2-Week Reusable ACUVUE 2 Vivid Style

NCT03431441
Conditions
Visual Acuity
Interventions
JJVC Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Two Daily Disposable Contact Lenses.

NCT01300065
Conditions
Myopia
Interventions
Experimental- Soflens, Marketed - Soflens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
15 Years to 40 Years
Enrollment
441 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Conditions
Refractive Error
Interventions
OPTI-FREE PureMoist
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of A Marketed Silicone Hydrogel Spherical Lens Used for Monovision Correction of Presbyopia

NCT04073186
Conditions
Visual Acuity
Interventions
ACUVUE® OASYS with Transitions™
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Jacksonville, Florida • Raytown, Missouri • New York, New York + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses

NCT01309867
Conditions
Myopia
Interventions
Investigational Toric Lens, PureVision Toric Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution

NCT01341977
Conditions
Healthy Contact Lens Wearers
Interventions
Alcon MPDS, ReNu Fresh MPS
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses

NCT02537522
Conditions
Contact Lens Base Curve (BC) Fit and Comfort
Interventions
Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Results available

Vistakon Investigational Contact Lenses Worn for Daily Wear

NCT00717249
Conditions
Myopia
Interventions
galyifilcon A control lens, galyfilcon A with a silver additive
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
20
States / cities
Fresno, California • Mission Viejo, California • Louisville, Colorado + 17 more
Completed Not applicable Interventional Results available

Comparison of New Contact Lens With Current Marketed Lens

NCT03360110
Conditions
Myopia
Interventions
Phoebe test lens, stenfilcon A lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Myopia
Interventions
galyfilcon A prototype lens, lotrafilcon B lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
2
States / cities
Jacksonville, Florida • Salem, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparative Study of Two Marketed Spherical Soft Contact Lenses

NCT01582789
Conditions
Refractive Error
Interventions
enfilcon A, senofilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 38 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
2
States / cities
Pismo Beach, California • San Diego, California
Conditions
Comfort
Interventions
Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in the Currently Marketed Resin Bottle., Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in a Clear Resin Bottle.
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Astigmatic Contact Lenses

NCT03086447
Conditions
Visual Acuity
Interventions
Investigational Contact Lens, Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
17
States / cities
Whittier, California • Jacksonville, Florida • Jacksonville Beach, Florida + 14 more
Completed Not applicable Interventional Results available

Clinical Evaluation of Two Daily Disposable Lenses in Neophytes

NCT00987623
Conditions
Myopia
Interventions
nelfilcon A contact lens, narafilcon A contact lens
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
Up to 45 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fort Washington, Pennsylvania
Conditions
Contact Lens Moisture
Interventions
FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Silicone Hydrogel Daily Disposable Contact Lenses

NCT02595502
Conditions
Vision Disorders
Interventions
JJVC Marketed Contact Lens (Test), Competitor Marketed Contact Lens (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
13
States / cities
Montgomery, Alabama • Fruit Cove, Florida • Sarasota, Florida + 10 more