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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Maximal Inspiratory Pressure Clear all
Recruiting Not applicable Interventional

A Study Investigating the Impact of IMT With CR On Exercise Responses In HF

NCT07086131
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
Powerbreathe
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inhaler Trainer Efficacy Study

NCT06461403
View directory record Official record
Conditions
Asthma, Copd, Acute Exacerbation of COPD
Interventions
Inhaler Trainer System, Initial Inhaler Use Assessment, Inhaler Use Instruction
Device · Other
Lead sponsor
Koronis Biomedical Technologies
Industry
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tongue Motor Recruitment During Exercise

NCT02687737
View directory record Official record
Conditions
Healthy
Interventions
Electromyography, Maximum expiratory pressure, Videofluoroscopy, Swallowing Tasks
Procedure · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy

NCT05350332
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation, Percutaneous Phrenic Nerve Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain

NCT00678717
View directory record Official record
Conditions
Chronic Pain
Interventions
Autonomic Evaluation
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Sep 25, 2026, 4:57 PM EDT
Terminated Not applicable Interventional

Effects of Chemoradiation and Surgery on Cardiopulmonary Fitness and Tumor Neoplastic Phenotype in Gastrointestinal Malignancies

NCT02235441
View directory record Official record
Conditions
Pathologically Proven Gastrointestinal Malignancy, Plan of Care Must Include Chemoradiation
Interventions
Cardiopulmonary Exercise Test (CPET)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Completed No phase listed Observational

Delineating Swallowing Impairment and Decline in ALS

NCT02962050
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Videofluoroscopic Swallowing Study (VFSS), Voluntary Peak Cough Flow Testing, Iowa Oral Performance Instrument, Capsaicin Challenge, Pulmonary Function Testing, Eating Assessment Tool 10, The Center for Neurologic Study Bulbar Function Scale
Procedure · Device · Drug + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

NCT05381818
View directory record Official record
Conditions
Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
Interventions
Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Effects of Inspiratory Muscle Training in Persons With Advanced Multiple Sclerosis

NCT03345199
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Inspiratory Muscle Trainer (IMT)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Multinight CPAP for Sleep Apnea Patients

NCT02635100
View directory record Official record
Conditions
Sleep Apnea, Sleep Disordered Breathing
Interventions
CPAP machine with MNT algorithm
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Training Using the O2 Trainer

NCT07005622
View directory record Official record
Conditions
Inspiratory Muscle Training, Blood Pressure
Interventions
O2 Trainer, Deep breathing
Other
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Conroe, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intermittent Hypoxia and Inspiratory Threshold Loading to Enhance Inspiratory Muscle Function

NCT03029559
View directory record Official record
Conditions
Intermittent Hypoxia
Interventions
Intermittent Hypoxia, Inspiratory Threshold Loading, Sham Intermittent Hypoxia
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

NCT06019949
View directory record Official record
Conditions
Spinal Cord Injuries, Respiration Disorders
Interventions
Transcutaneous spinal cord stimulator, Respiratory Training
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Not listed Not applicable Interventional

Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19

NCT04887272
View directory record Official record
Conditions
Covid19
Interventions
Supervised Exercise Training Protocol, Inspiratory Muscle and Exercise Training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Sep 25, 2026, 4:57 PM EDT
Completed No phase listed Observational

Preoperative Maximum Inspiratory Pressure and Outcomes After Interscalene Block in Obese Patients

NCT06549244
View directory record Official record
Conditions
Dyspnea After Interscalene Nerve Block
Interventions
Maximum Inspiratory Pressure monitoring
Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Training in Postmenopausal Women

NCT06459674
View directory record Official record
Conditions
Postmenopausal Symptoms, Aging, Obesity
Interventions
PrO2 Fit (IMT Trainer)
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Remote Pulmonary Function Testing and Nurse Coaching in ALS

NCT04490148
View directory record Official record
Conditions
ALS
Interventions
remote pulmonary function testing, standard pulmonary function testing, Nurse Respiratory Health Coaching (NRHC)
Device · Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Phase 2 Interventional

Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension

NCT03814317
View directory record Official record
Conditions
Sarcoidosis, Precapillary Pulmonary Hypertension, Interstitial Lung Disease
Interventions
Inhaled Treprostinil
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Phase 4 Interventional Results available

Aerosolized Endotracheal Lidocaine to Avoid Intracranial Pressure Spikes in Patients With Severe Traumatic Brain Injury

NCT05058677
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
aerosolized 2% lidocaine (20mg/ml), instilled 0.9% sodium chloride (NS), instilled 2% lidocaine solution, Endotracheal Suctioning (ETS)
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 16 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

NCT05945355
View directory record Official record
Conditions
Asthma in Children, Obesity, Pediatric Obesity, Pediatric Asthma
Interventions
Pro2 - Low Dose - 40% of participant's MIP, Pro2 - High Dose - 75% of participant's MIP, Pro2 - SHAM - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
6 Years to 17 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

NCT04848675
View directory record Official record
Conditions
Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
Inspiratory muscle strength training, Brisk walking
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training

NCT01977222
View directory record Official record
Conditions
Congenital Heart Disease, Single Ventricle
Interventions
THRESHOLD(TM) INSPIRATORY MUSCLE TRAINER
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Active, not recruiting Phase 2 Interventional

Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury

NCT04458324
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Buspirone Hydrochloride, Buspirone placebo, Noninvasive Ventilation (NIV), Sham Non-invasive ventilation (NIV), Functional Electrical Stimulation Row Training (FESRT)
Drug · Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Remote Pulmonary Function Testing in Amyotrophic Lateral Sclerosis (Pilot)

NCT03214224
View directory record Official record
Conditions
ALS
Interventions
remote pulmonary function testing, standard pulmonary function testing
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 25, 2026, 4:57 PM EDT