- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
- Interventions
- Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
- Drug · Diagnostic Test
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
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Showing 1–24
of 65
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Cardiovascular Diseases, Hyperlipidemias
- Interventions
- Lipid Challenge, Glucose Challenge, Mixed Meal Challenge
- Dietary Supplement
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Diabetes Mellitus, Type 1
- Interventions
- Closed-loop session
- Device
- Lead sponsor
- Sansum Diabetes Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Santa Barbara, California
- Conditions
- Liver Diseases
- Interventions
- Novel MRI Software, Ensure Plus Nutrition Shake
- Device · Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 7 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2027 – 2029
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Obesity
- Interventions
- Meal challenge
- Other
- Lead sponsor
- North Dakota State University
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fargo, North Dakota
- Conditions
- Genetic Predisposition, Metabolic Diseases, Type 2 Diabetes
- Interventions
- oral semaglutide, Mixed Meal Tolerance Test (MMTT)
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Obesity, Overweight, Weight Loss
- Interventions
- Weight Management Intervention
- Behavioral
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 3
- States / cities
- Freeport, Illinois • Hillsboro, Illinois • Marshall, Illinois
- Conditions
- Nutrition, Healthy, Mental Health Wellness 1, Diabetes Mellitus Risk, Obesity
- Interventions
- Brighter Bites (BB) Produce Distribution, Brighter Bites (BB) Nutrition Education, Create Healthy Futures (CHF) Weekly Wellness Groups, Create Healthy Futures (CHF) Web-Based Module
- Behavioral
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 379 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Polycystic Ovary Syndrome (PCOS)
- Interventions
- Metabolic response to protein source
- Other
- Lead sponsor
- University of Arkansas, Fayetteville
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Fayetteville, Arkansas
- Conditions
- Alcohol Use, College Drinking, Anxiety
- Interventions
- IMPROVE, HET
- Behavioral
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Anxiety, Substance Use Disorders
- Interventions
- IMPROVE, PHET
- Behavioral
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Erythema, Inflammation
- Interventions
- Pomegranate Juice, Placebo Juice
- Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 65 Years · Male only
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Healthy, Pre Hypertension
- Interventions
- Exercise capacity VO2 max determination, Standardized meals, Exercise challenge, Metoprolol Succinate ER
- Other · Dietary Supplement · Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Overweight, Obesity
- Interventions
- Phone-based sessions (28 total) on a structured schedule, Phone-based sessions upon request, Weight self-monitoring, Dietary and physical activity self-monitoring, Scheduled tailored interventionist feedback, Dietary goals, Meal replacements, Physical activity goals, Toolbox, Challenges, Tailored interventionist feedback upon request
- Behavioral
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Gastroparesis With Diabetes Mellitus
- Interventions
- FreeStyle Libre 3 continuous glucose monitoring sensor, Nutritional drink
- Device · Other
- Lead sponsor
- Samita Garg
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Interventions
- TI Inhalation Powder and Humalog (Amendment 1), TI Inhalation Powder (original protocol)
- Drug
- Lead sponsor
- Mannkind Corporation
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Santa Barbara, California
- Conditions
- Asthma, Allergic Asthma, Non-allergic Asthma
- Interventions
- Nutritional approach for asthma, Low Caloric Shake, whole lung allergen challenge
- Dietary Supplement · Biological
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2027
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Type 1 Diabetes Mellitus
- Interventions
- Faster Insulin Aspart (Fiasp®)
- Drug
- Lead sponsor
- Mountain Diabetes and Endocrine Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Asheville, North Carolina
- Conditions
- Healthy, Healthy Aging
- Interventions
- Fatty meal to challenge the physiological chronobiome in healthy young and old
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2028
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Feeding, Metabolism, Indirect Calorimetry, Blood Flow Velocity, Pulse Wave Analysis, Pulse Wave Velocity, Carbohydrate Metabolism, Fatty Acid Metabolism, Healthy Participants
- Interventions
- Mixed Meal Feeding Challenge
- Other
- Lead sponsor
- George Washington University
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Type 1 Diabetes Mellitus With Hypoglycemia
- Interventions
- Glucagon, Insulin
- Drug
- Lead sponsor
- Abvance Therapeutics
- Industry
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Changes in Physical Fitness, Changes in Diet, Food, and Nutrition Habits, Changes in Child Health
- Interventions
- THINK Program
- Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 8 Years to 12 Years
- Enrollment
- 73 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Coral Gables, Florida
- Conditions
- Dietary Modification
- Interventions
- Tart cherry Juice, High-fat meal, Exercise
- Dietary Supplement · Other
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 18 Years to 30 Years · Male only
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Obesity, Rapid Eating Style
- Interventions
- RePace Intervention, Usual Care Control
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 4 Years to 7 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania