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ClinicalTrials.gov public records Last synced Oct 4, 2026, 9:24 PM EDT

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Showing 25–48 of 61 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Mean Arterial Pressure (MAP) Clear all
Withdrawn Not applicable Interventional

Brain Autoregulation Research Study

NCT07221721
View directory record Official record
Conditions
Hypotension During Surgery, Hypotension Postprocedural
Interventions
Surgery with Active MAP Management, Surgery without Active MAP Management
Device · Other
Lead sponsor
Jennie E Minnich
Other
Eligibility
30 Days to 30 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation Study of Mean Arterial Pressure (MAP) Parameter of Masimo INVSENSOR00073

NCT06334055
View directory record Official record
Conditions
Healthy
Interventions
Masimo INVSENSOR00073
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 40 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 4, 2026, 9:24 PM EDT
Terminated Not applicable Interventional

Targeting Abdominal Perfusion Pressure in Septic Shock

NCT03582046
View directory record Official record
Conditions
Acute Kidney Injury, Septic Shock, Resuscitations
Interventions
Abdominal Perfusion Pressure (APP), Mean Arterial Pressure (MAP)
Device
Lead sponsor
Potrero Medical
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Little Rock, Arkansas • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 4, 2026, 9:24 PM EDT
Terminated Not applicable Interventional Results available

Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.

NCT01214057
View directory record Official record
Conditions
Chronic Rhinosinusitis
Interventions
Propofol and Remifentanyl, Sevoflurane and Remifentanyl
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Phase 1Phase 2 Interventional

Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial

NCT01242462
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Conventional Pressure Controlled SIMV, Mid-frequency Ventilation
Procedure · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 7 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

NCT02701582
View directory record Official record
Conditions
Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
Interventions
Phenylephrine, Epinephrine, Albumin, Voluven, Normal Saline, Packed Red Blood Cells, FloTrac Monitor
Drug · Other · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
15 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Non-invasive Measurement of Cerebral Dynamic Autoregulation

NCT02442856
View directory record Official record
Conditions
Stroke
Interventions
Thigh Cuff
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Fluid Responsiveness Evaluation in Sepsis-associated Hypotension

NCT02837731
View directory record Official record
Conditions
Sepsis, Hypotension
Interventions
Treatment Starling SV monitor
Device
Lead sponsor
Cheetah Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
11
States / cities
San Francisco, California • Denver, Colorado • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Oct 4, 2026, 9:24 PM EDT
Terminated Not applicable Interventional Results available

Safety of Optimal PEEP in NSICU Patients

NCT03862027
View directory record Official record
Conditions
Respiratory Failure, Intracranial Hypertension
Interventions
Esophageal Balloon catheter
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional

Will a Real Time Advisory for Double Low State Change Clinical Behavior and Impact Outcomes

NCT01545596
View directory record Official record
Conditions
Ability to Influence Behavior, Information Systems
Interventions
Notification Group
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20,237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 4, 2026, 9:24 PM EDT
Not yet recruiting No phase listed Observational

Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients

NCT07573306
View directory record Official record
Conditions
Cardiac Surgery
Interventions
SpHb monitor
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 4, 2026, 9:24 PM EDT
Completed No phase listed Observational

Randomized Trial of Alerts in Patients Demonstrating a "Triple Low"

NCT00998894
View directory record Official record
Conditions
Low Bispectral Index, Low Mean Arterial Blood Pressure, Low End-tidal Anesthetic Concentration
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
9,846 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Protocolized Care for Early Septic Shock

NCT00510835
View directory record Official record
Conditions
Sepsis, Severe Sepsis, Septic Shock
Interventions
Early Goal Directed Therapy (EGDT), Protocolized Standard Care (PSC), Usual Care (UC)
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
31
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Phase 1 Interventional Results available

Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study

NCT01393782
View directory record Official record
Conditions
Septic Shock
Interventions
Angiotensin II
Drug
Lead sponsor
George Washington University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 4, 2026, 9:24 PM EDT
Withdrawn Not applicable Interventional

Cardiac Output Monitoring in Burn Patients

NCT02404597
View directory record Official record
Conditions
Burns
Interventions
NICOM (non-invasive cardiac output monitor)
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional

Peri-Operative Morbidity and Quality of Life After Coronary Artery Bypass Graft (CABG)

NCT00248885
View directory record Official record
Conditions
Coronary Artery Bypass Graft Surgery
Interventions
Regulating Mean Arterial Pressure during cardiopulmonary bypass
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1994
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2008 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Early Phase 1 Interventional

Vasopressor Outcomes in Spine Surgery

NCT06053398
View directory record Official record
Conditions
Hypotension
Interventions
Phenylephrine, Norepinephrine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional

Trial of Antimicrobial Restraint in Presumed Pneumonia

NCT04438187
View directory record Official record
Conditions
Healthcare-Associated Pneumonia, Sepsis
Interventions
antimicrobial initiation
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 4, 2026, 9:24 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study

NCT06094816
View directory record Official record
Conditions
Salt-Sensitivity of Blood Pressure
Interventions
Furosemide (Diuretic), Hypertonic Saline Infusion
Drug · Other
Lead sponsor
University of Delaware
Other
Eligibility
40 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 4, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

A Pilot Trial of Continuous Portable Postoperative Hemodynamic And Saturation Monitoring On Hospital Wards

NCT04574908
View directory record Official record
Conditions
Hemodynamic Instability, Respiratory Complications of Care
Interventions
ViSi device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 4, 2026, 9:24 PM EDT
Completed No phase listed Observational

Cardiac Function as Measured by Non-invasive Electrical Velocimetry Cardiac Monitor in Hospitalized Children

NCT01030445
View directory record Official record
Conditions
Cardiac Output, Blood Pressure
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Oct 4, 2026, 9:24 PM EDT
Terminated Not applicable Interventional

Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury

NCT02232165
View directory record Official record
Conditions
Acute Spinal Cord Injury
Interventions
Hypotension avoidance, Induced hypertension
Other
Lead sponsor
University of Calgary
Other
Eligibility
16 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 4, 2026, 9:24 PM EDT
Completed No phase listed Observational

Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock

NCT03014063
View directory record Official record
Conditions
Septic Shock
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 4, 2026, 9:24 PM EDT
Not listed Not applicable Interventional

A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients

NCT00459160
View directory record Official record
Conditions
Hemorrhagic Shock, Trauma, Wounds, Penetrating, Shock, Traumatic, Multiple Trauma
Interventions
Intraoperative Hypotensive Resuscitation
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 45 Years
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2010 · Synced Oct 4, 2026, 9:24 PM EDT