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Conditions: Diabetic Foot Ulcer
Interventions: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Dysphagia
Interventions: Fiberoptic Endoscopic Evaluation of Swallowing, Videofluoroscopic Swallowing Study, Voluntary Peak Cough Flow Testing, Iowa Oral Performance Instrument, Capsaicin Challenge, Pulmonary Function Testing, Voicing Tasks; Procedure · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 90 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Rheumatoid Arthritis, Healthy Controls
Interventions: Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity, Muscle Biopsy, Body Composition, Cardiopulmonary Exercise Test (CPET), Strength Testing, Questionnaires, Skeletal Muscle Biomechanical Property Assessment; Other
Lead sponsor: Duke University; Other
Eligibility: 25 Years to 75 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Breast Cancer
Interventions: high field strength magnetic resonance imaging, magnetic resonance spectroscopic imaging, chemical exchange saturation transfer magnetic resonance imaging, diffusion-weighted magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging; Procedure
Lead sponsor: Vanderbilt-Ingram Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Lymphedema
Interventions: Exercise Intervention, Weight Loss Intervention; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: Up to 80 Years · Female only
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid, Muscle Weakness
Interventions: Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall; Diagnostic Test · Other
Lead sponsor: Carroll University; Other
Eligibility: 20 Years to 35 Years · Female only
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Waukesha, Wisconsin

Conditions: Oral Cancer, Head and Neck Cancer
Interventions: Tongueometer; Other
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Spinal Cord Injury Cervical
Interventions: Blood flow-restricted resistance exercise; Behavioral
Lead sponsor: Quality Living, Inc.; Other
Eligibility: 19 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: PTSD, Alcohol; Use, Problem
Interventions: Seeking Safety + Signs of Safety toolkit, Treatment as usual; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Lymphoma, Sarcoma
Interventions: Electrocardiogram, Echocardiogram, LVEF echocardiogram, Apple Watch, Biospecimen collection, Questionnaires, Cardio-pulmonary exercise test, 6 minute walk test, Grip strength test; Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: HIV, Aging
Interventions: Customized activity plan, Customized nutrition plan; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 50 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Guillain-Barre Syndrome
Interventions: Peripheral nerve ultrasound, Measurement of strength; Diagnostic Test
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Arthrogryposis, Craniofacial Abnormalities
Interventions: Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form, Strength, Joint ROM, Girth and Length Measurements, Study Physical Examination, Observational Gait Analysis, Mental Health Interview; Other · Procedure
Lead sponsor: Freeman-Sheldon Research Group, Inc.; Other
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Buckhannon, West Virginia

Conditions: Pelvic Pain, Pelvic Floor Dysfunction, Voiding Dysfunction
Interventions: Home Pelvic Floor Trainer; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 8 Years to 18 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Coagulopathy
Interventions: ROTEM, Cryoprecipitate, RiaSTAP; Device · Other · Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Preterm Premature Rupture of the Membranes, Physical Activity
Interventions: Moderate Activity; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Late-onset Pompe Disease
Interventions: Respiratory muscle strength measurements by different techniques.; Procedure
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Amyotrophic Lateral Sclerosis, Parkinson Disease, Dysphagia
Interventions: Videofluoroscopic Swallowing Examination, Tongue Strength Measurement; Diagnostic Test · Other
Lead sponsor: University Health Network, Toronto; Other
Eligibility: 18 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Ischemic Stroke, Brain Hemorrhage
Interventions: Thromboelastography; Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Acute Kidney Injury, Critical Illness Myopathy, Dialysis; Complications
Interventions: Musculoskeletal ultrasound, Assessments of muscle strength and physical function, Metabolomics; Diagnostic Test
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 89 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Iowa City, Iowa • Lexington, Kentucky • Albuquerque, New Mexico

Conditions: Pectus Excavatum
Interventions: Magnetic Mini-Mover Procedure (3MP), Magnatract (external magnet in a removable external brace), 3MP (Magnetic Mini-Mover Procedure); Device · Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 8 Years to 14 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Breast Cancer
Interventions: Baseline Fitness Test, Questionnaires, Individualized Exercise Program, Written Materials; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 21 Years and older · Female only
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Heart Failure
Interventions: Placebo, Sodium Nitrite, Accelerometer, Cardiac Exercise Training; Drug · Device · Other
Lead sponsor: Barry Borlaug; Other
Eligibility: 40 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Pain, Atrophic, Goals, Impairment, Infiltration, Injury, Muscle Weakness, Pain, Pathology, Shoulder Pain, Syndrome, Tendinopathy
Interventions: Subacromial injection, Physical Therapy; Procedure · Other
Lead sponsor: University of Oregon; Other
Eligibility: 21 Years to 45 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Eugene, Oregon

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Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration

Improving Diagnostic Standards in Dysphagia

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

Ultra High Field MRI and MRS Techniques in Diagnosing Breast Cancer

The Women In Steady Exercise Research (WISER) Survivor Trial

Muscle Function After Childbirth

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

Blood Flow-restricted Resistance Exercise to Promote Muscle Strength and Use in Adults With Incomplete Spinal Cord Injury

Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma

WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)

Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older

Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome

Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions

HOme PElvic Floor Improvement Trainer Trial

Trial of RiaSTAP Versus Cryoprecipitate to Lower Operative Transfusions

A Comparison of Bed Rest Versus Moderate Activity in Preterm Premature Rupture of Membranes (PPROM)

A Study of Respiratory Muscle Strength in Patients With Late-onset Pompe Disease (LOPD)

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

Prospective Analysis of the Use of TEG in Stroke Patients

Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

Magnetic Mini-Mover Procedure to Treat Pectus Excavatum

Part II: Exercise in Hispanic Breast Cancer Survivors

Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy