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ClinicalTrials.gov public records Last synced Sep 26, 2026, 10:38 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2 Interventional Results available

Lidocaine as an Endotracheal Tube (ETT) Cuff Media

NCT03343080
Conditions
Cardiac Disease
Interventions
1.8% lidocaine plus 0.76% sodium bicarbonate, Air
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Lung Carcinoma
Interventions
Educational Intervention, Questionnaire Administration
Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Pressure Ulcer
Interventions
DabirAIR alternating pressure overlay
Device
Lead sponsor
Dabir Surfaces Inc
Industry
Eligibility
18 Years and older
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

The Interaction of Social Factors With Air Pollution

NCT02206750
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean Air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 33 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Body Weight Supported Treadmill Training in Persons With Multiple Sclerosis

NCT01992679
Conditions
Multiple Sclerosis
Interventions
Exercise group
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Urbana-Champaign, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Maternal Oxygen Supplementation for Intrauterine Resuscitation

NCT05681624
Conditions
Fetal Distress, Fetal Hypoxia, Labor and Delivery Complication
Interventions
Maternal oxygen supplementation, Room air
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
2,252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Cystic Fibrosis in Children
Interventions
Infant PFT, Lung Clearance Index, Passive tidal breathing
Diagnostic Test
Lead sponsor
Indiana University
Other
Eligibility
1 Month to 5 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wood Smoke Interventions in Native American Populations

NCT02240069
Conditions
Respiratory; Disorder, Functional, Impaired, Respiratory Infection Other
Interventions
Education (Tx1), Air Filtration Unit Treatment (Tx2), Placebo Intervention (Tx3)
Behavioral · Device
Lead sponsor
University of Montana
Other
Eligibility
55 Years and older
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Missoula, Montana
Suspended Not applicable Interventional Accepts healthy volunteers

Cardiovascular Effects of Exposure to Wood Smoke in Healthy Human Adults

NCT04297761
Conditions
Healthy
Interventions
Filtered Air, Wood Smoke
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Spinal Cord Injury
Interventions
Acute Intermittent Hypoxia (AIH), SHAM-Intermittent Room Air
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Hypoxia on Subconcussive Head Impacts

NCT04624152
Conditions
Trauma, Brain
Interventions
Soccer heading
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Cancer
Interventions
High-flow Oxygen, Low-flow Oxygen, High-flow Air, Low-flow Air
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Myocardial Infarction
Interventions
Technetium Tc99m Sestamibi
Drug
Lead sponsor
Lantheus Medical Imaging
Industry
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
4
States / cities
Birmingham, Alabama • Boston, Massachusetts • Nashville, Tennessee + 1 more
Conditions
Pediatric Asthma
Interventions
Healthy home intervention
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
Up to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio
Conditions
Bronchial Stents
Interventions
Bronchoscopy
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Angiogram, Percutaneous Coronary Intervention
Interventions
RadAR EasyCLik plus ®-STF hemostatic pad, TR BAND® Compression device plus ®-STF hemostatic pad, SoftSeal®-STF hemostatic pad, VascBand™ Hemostat
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Nitric Oxide, Cardiac Surgery, Cardiopulmonary Bypass, Adult Patients Undergoing Cardiovascular Surgery With Cardiopulmonary Bypass
Interventions
Nitric Oxide Gas, Standard Care Arm
Drug
Lead sponsor
Xijing Hospital
Other
Eligibility
18 Years and older
Enrollment
3,650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
COPD, Eosinophilia
Interventions
Air purifier, Sham air purifier
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting Not applicable Interventional

Social Identity Mapping for Adolescent Recovery

NCT07474207
Conditions
Alcohol Use Disorder (AUD)
Interventions
SIM-AiR
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Synergistic Effects of AIH and FES in Persons With MS

NCT06413602
Conditions
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
Interventions
Acute Intermittent Hypoxia, Neuromuscular Electrical Stimulation
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Obstructive Sleep Apnea
Interventions
Mild Intermittent Hypoxia, Sham MIH
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Newborn, Environmental Exposure
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 12 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts