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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mediterranean Diet -- Control Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

NCT02706262
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet, Annual Follow-up Visits
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet, Weight Loss, and Cognition in Obese Older Adults

NCT03129048
View directory record Official record
Conditions
Cognition, Obese Older Adults, Mediterranean Diet
Interventions
MedDiet
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional

SUSTAIN: Behavior Change and Nutrition Security for CKMS

NCT06589336
View directory record Official record
Conditions
Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions
Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

NCT03146156
View directory record Official record
Conditions
Obesity, Lifestyle-related Condition, Macrosomia, Fetal
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
4
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Results available

ACT1ON Phase 2 (SMART Pilot) and Phase 3 (Efficacy Trial Development)

NCT03651622
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Overweight and Obesity
Interventions
Hypocaloric, low carbohydrate diet, Hypocaloric, moderate low fat diet, Mediterranean diet, no caloric restriction
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
19 Years to 30 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Palo Alto, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Sep 25, 2026, 6:28 PM EDT
Terminated Not applicable Interventional

Effects of Mediterranean Diet Intervention in Diabetic Heart Disease

NCT03757845
View directory record Official record
Conditions
Diabetes Complications, Cardiovascular Diseases
Interventions
Mediterranean Diet
Other
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and Mushrooms

NCT04259229
View directory record Official record
Conditions
Diet, Healthy
Interventions
Mediterranean Diet -- Mushrooms, Mediterranean Diet -- Control
Other
Lead sponsor
Purdue University
Other
Eligibility
30 Years to 69 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Results available

Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

NCT03472664
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
low carbohydrate/high fat diet, low fat/high carbohydrate diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional

Lifestyle Modification Program to Reduce Risk of Coronary Heart Disease in Latina Women With Diabetes

NCT00233259
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Type 2
Interventions
Mediterranean Diet, Physical Activity, Stress Management, Social Support, Smoking Cessation, Control group
Behavioral · Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
30 Years to 75 Years · Female only
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 24, 2011 · Synced Sep 25, 2026, 6:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Cooking for Health Optimization and Disease Prevention (CHOP) Trial

NCT07011459
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Cooking class, Standard of care
Behavioral · Other
Lead sponsor
Tulane University
Other
Eligibility
55 Years to 120 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 25, 2026, 6:28 PM EDT
Not listed Not applicable Interventional

Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome

NCT05500976
View directory record Official record
Conditions
Dietary Habits
Interventions
Semi-controlled dietary intervention - Western, Semi-controlled dietary intervention - MiniMed
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 69 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Results available

Trial of Specific Carbohydrate and Mediterranean Diets to Induce Remission of Crohn's Disease

NCT03058679
View directory record Official record
Conditions
Crohn Disease
Interventions
Diet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
35
States / cities
Tucson, Arizona • San Francisco, California • Denver, Colorado + 27 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 25, 2026, 6:28 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Whole Egg Intake and the Mediterranean Diet

NCT02737293
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Control Diet, Med Diet, Med Diet + Whole Egg
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
20 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

NCT04293224
View directory record Official record
Conditions
Obesity, Body Weight
Interventions
DGA Mediterranean diet pattern, energy balance, DGA Mediterranean diet pattern, negative energy balance, TAD diet pattern, negative energy balance
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
19 Years to 64 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits

NCT02941757
View directory record Official record
Conditions
Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
Interventions
Mediterranean diet Intervention
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years and older
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Phase 4 Interventional Results available

Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity

NCT04614545
View directory record Official record
Conditions
Obesity
Interventions
Phentermine 37.5 Mg, Dietary program, Exercise program
Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Sep 25, 2026, 6:28 PM EDT
Not listed Not applicable Interventional

Perioperative Optimization With Enhanced Recovery

NCT04504266
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
POWER
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Results available

Effect of Whole Fruit on Glycemic Control in Adults With Type 2 Diabetes

NCT03758742
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
High-Fruit Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 25, 2026, 6:28 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Precision Nutrition and Metabolic Function

NCT04131166
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Mediterranean diet, Low-carbohydrate, ketogenic diet, Low-fat diet, Annual follow-up testing for 5 years
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2029
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Healthy Diet and Lifestyle Study II

NCT05132686
View directory record Official record
Conditions
Intra-Abdominal Fat
Interventions
IER+MED, MED/DER
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
35 Years to 69 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Meals Study for Amyotrophic Lateral Sclerosis and Parkinson's Disease

NCT07625605
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Parkinson's Disease (PD)
Interventions
The MIND diet
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
30 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Elizabethton, Tennessee • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Not listed Not applicable Interventional

Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis

NCT05291299
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Anti-inflammatory diet, Control/Standard of Care
Behavioral · Other
Lead sponsor
Attune Health Research, Inc.
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Sep 25, 2026, 6:28 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study

NCT07509502
View directory record Official record
Conditions
Type 2 Diabetes (T2DM), Obesity & Overweight
Interventions
Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 25, 2026, 6:28 PM EDT
Not listed Not applicable Interventional

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

NCT05138198
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions
Mediterranean Diet & Physical Activity, Usual Care
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
40 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 25, 2026, 6:28 PM EDT