- Conditions
- Parkinson's Disease, Essential Tremor, Dystonia
- Interventions
- Medtronic Activa Tremor Control System, Deep Brain Stimulation
- Device · Procedure
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2029
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
Search Results
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Showing 1–24
of 25
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Dystonia, Focal Dystonia, Musician's Dystonia
- Interventions
- DBS surgery, Medtronic Activa Rechargeable System
- Procedure · Device
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 22 Years to 100 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2029
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Posttraumatic Stress Disorder
- Interventions
- DBS of the Basolateral Nucleus of the Amygdala, Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
- Procedure · Device
- Lead sponsor
- VA Greater Los Angeles Healthcare System
- Federal
- Eligibility
- 25 Years to 70 Years · Male only
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2025
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- TBI (Traumatic Brain Injury)
- Interventions
- Deep brain stimulation
- Device
- Lead sponsor
- Jaimie M. Henderson
- Other
- Eligibility
- 22 Years to 60 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Essential Tremor
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Manhasset, New York
- Conditions
- Parkinson's Disease
- Interventions
- Activa PC+S
- Device
- Lead sponsor
- Vibhor Krishna
- Other
- Eligibility
- 22 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Alzheimer Disease
- Interventions
- DBS-f on, DBS-f off
- Device
- Lead sponsor
- Functional Neuromodulation Ltd
- Industry
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 6
- States / cities
- Phoenix, Arizona • Sun City, Arizona • Gainesville, Florida + 3 more
- Conditions
- Treatment Resistant Major Depressive Disorder
- Interventions
- Activa Tremor Control Sys (DBS Implant), Randomized, staggered withdrawal phase
- Device · Other
- Lead sponsor
- Wayne Goodman MD
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Obsessive-Compulsive Disorder
- Interventions
- Active DBS, Sham DBS
- Device
- Lead sponsor
- Butler Hospital
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2024
- U.S. locations
- 9
- States / cities
- Redwood City, California • Washington D.C., District of Columbia • Gainesville, Florida + 6 more
- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Week 0 Medtronic 3387 electrodes/Activa PC amygdala DBS, Week 12 Medtronic 3387 electrodes/Activa PC amygdala DBS
- Device
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 25 Years to 65 Years · Male only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Parkinson's Disease, Isolated Dystonia
- Interventions
- Activa PC+S
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Parkinson Disease
- Interventions
- Implantable pulse generator (deep brain stimulator)
- Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 20 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Tourette Syndrome
- Interventions
- Medtronic Activa Deep Brain Stimulation System
- Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 15 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2023
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Parkinson Disease
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Tourette Syndrome
- Interventions
- Continuous DBS, Responsive Brain Stimulation (RBS Setting)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2023
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Obsessive-Compulsive Disorder
- Interventions
- Medtronic Activa Deep Brain Stimulation
- Device
- Lead sponsor
- Butler Hospital
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2012
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Tinnitus
- Interventions
- Deep Brain Stimulation (DBS)
- Device
- Lead sponsor
- Paul Larson
- Other
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Obsessive-Compulsive Disorder
- Interventions
- Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
- Device · Other
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2027
- U.S. locations
- 3
- States / cities
- Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
- Conditions
- Treatment Resistant Depression
- Interventions
- Medtronic Activa PC+S System
- Device
- Lead sponsor
- Emory University
- Other
- Eligibility
- 25 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2029
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Parkinson's Disease, Mild Cognitive Impairment
- Interventions
- stimulation ON, stimulation OFF
- Device
- Lead sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Obesity
- Interventions
- Deep Brain Stimulation of the Lateral Hypothalamic Area
- Device
- Lead sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- Other
- Eligibility
- Not listed
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Epilepsy
- Interventions
- Activa™ PC and Percept™ PC Neurostimulation Systems
- Device
- Lead sponsor
- MedtronicNeuro
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 7
- States / cities
- Los Angeles, California • San Francisco, California • Atlanta, Georgia + 4 more
- Conditions
- Parkinson's Disease
- Interventions
- Medtronic Activa PC+S System with Chronic Neural Recording, Effort-Reward Decision-Making Task, Prefrontal Cortex Stimulation, Tablet-Based Mood Tracking (Immediate Mood Scaler)
- Device · Behavioral · Other
- Lead sponsor
- Simon J. Little, MBBS, PhD
- Other
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Parkinson's Disease
- Interventions
- Activa PC+S
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota