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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:18 PM EDT

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Showing 1–24 of 51 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Mental Health and Substance Use Resources Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 30, 2026, 1:18 PM EDT
Recruiting Not applicable Interventional

Supportive Hospital-Based Intervention for Firearm Trauma

NCT06712940
View directory record Official record
Conditions
Gun Violence Prevention, Adolescent Behavior
Interventions
Motivational Interviewing and Firearm Safety Training, with Case Management
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
16 Years to 24 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional

Project IntERact V2

NCT05109325
View directory record Official record
Conditions
Firearm Violence, Firearm Carriage, Injury Prevention
Interventions
IntERact
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 30 Years
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Ann Arbor, Michigan • Flint, Michigan • Saginaw, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linkage of Transgender Individuals to PrEP

NCT03191474
View directory record Official record
Conditions
HIV Seronegativity, Linkage
Interventions
T-POWr Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brief Intervention for Rural Women at High Risk for HIV/HCV

NCT01840722
View directory record Official record
Conditions
Acquired Immune Deficiency Syndrome Virus, Hepatitis C, Drug Abuse
Interventions
MI-based HIV Risk Reduction
Other
Lead sponsor
Michele Staton
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Hazard, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

NCT05345951
View directory record Official record
Conditions
Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College, College Drinking, Teen Drinking
Interventions
e-PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
1,980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of an Adapted STD Screening and Risk Reduction Intervention

NCT02513225
View directory record Official record
Conditions
Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions
Project EMPWR, Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 49 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Fort Apache, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 30, 2026, 1:18 PM EDT
Active, not recruiting Not applicable Interventional

Addressing Barriers to Care for Substance Use Disorder Trial

NCT06729957
View directory record Official record
Conditions
Drug Use Disorders, Alcohol-Related Disorders, Substance Use Disorder (SUD)
Interventions
Care Navigation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Results available

Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries

NCT05821699
View directory record Official record
Conditions
Sports Medicine Injuries
Interventions
LCS (Life Care Specialist), Standard of Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
15 Years to 45 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Results available

Life Care Specialists (LCS) With a Focus on Patient Pain Management and Prevention of Substance Misuse

NCT04154384
View directory record Official record
Conditions
Opioid Use
Interventions
Life Care Specialist (LCS) Intervention, Clinical Coordination with Referrals, Pilot Study of Pain Management Strategies
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: PRE-FAIR

NCT05380440
View directory record Official record
Conditions
Opioid-Related Disorders, Stimulant-Related Disorder, Child Neglect, Mental Health Impairment
Interventions
Prevention Adaptation of Families Actively Improving Relationships (PRE-FAIR), Standard Case Management and Referral
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
16 Years to 30 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Health and COVID-19

NCT05074693
View directory record Official record
Conditions
Anxiety Depression
Interventions
EASE app, INSIGHT (Control) App
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

90-Day Online Substance Use Program

NCT03069118
View directory record Official record
Conditions
Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
Interventions
Treatment - Workit Health Online Program, Control - Resource List
Behavioral
Lead sponsor
Workit Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Results available

Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth

NCT03910218
View directory record Official record
Conditions
Behavior, Risk
Interventions
NCM4HIV, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
16 Years to 25 Years
Enrollment
474 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 30, 2026, 1:18 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Training Church Leaders in Mental Health First Aid

NCT03649776
View directory record Official record
Conditions
Stigma
Interventions
Mental Health First Aid
Other
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
21 Years and older
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 30, 2026, 1:18 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Family-Focused Study to Support Medication for Opioid Use Disorder

NCT07451197
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
Interventions
FamilyCHESS, Standard of Care
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
2
States / cities
Chicago, Illinois • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adaptive Preventive Intervention for College Alcohol Use

NCT03930524
View directory record Official record
Conditions
College Student Drinking
Interventions
Personalized Normative Feedback (PNF), Self-Monitoring (SM), Web-BASICS, Health Promotion Consultation, M-Bridge Online Health Coach
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 21 Years
Enrollment
891 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 30, 2026, 1:18 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Client-Centered Care Coordination for Black Men Who Have Sex With Men

NCT06056544
View directory record Official record
Conditions
HIV Prevention, HIV Pre-exposure Prophylaxis
Interventions
Client Centered Care Coordination
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Male only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Recruiting Not applicable Interventional

Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

NCT06311838
View directory record Official record
Conditions
Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions
Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 24 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional Results available

SafetyNet Program for Opioid Use Disorder (OUD)

NCT04253782
View directory record Official record
Conditions
Opioid-Use Disorder (OUD)
Interventions
Team Intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 130 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Phase 2 Interventional

Efficacy Trial of Warrior Check-Up

NCT01128140
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Substance Abuse, Substance Dependence
Interventions
Motivational Enhancement Therapy, Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 30, 2026, 1:18 PM EDT
Completed Not applicable Interventional

The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services

NCT04295876
View directory record Official record
Conditions
HIV/AIDS
Interventions
The BRIDGES Project Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 30, 2026, 1:18 PM EDT
Active, not recruiting Not applicable Interventional

upREACH Perinatal Home Visitation Program

NCT06133829
View directory record Official record
Conditions
Pregnancy, Postpartum
Interventions
upREACH Home Visitation Program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Female only
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 30, 2026, 1:18 PM EDT
Active, not recruiting Not applicable Interventional

Leveraging Parents and Peers to Increase Recovery Capital in Emerging Adults

NCT06414993
View directory record Official record
Conditions
Polysubstance Drug Use (Indiscriminate Drug Use)
Interventions
Contingency Management for Emerging Adults (CM-EA), Standard Peer Recovery Support Services (PRSS) +Vocational/Educational (V/E) Skill Building services
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
8
States / cities
Hiram, Georgia • Bloomington, Illinois • Granite City, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Sep 30, 2026, 1:18 PM EDT