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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:31 AM EDT

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Showing 25–48 of 116 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Mental stress test Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

MicroRNA Correlates of Childhood Maltreatment and Suicidality

NCT04923685
View directory record Official record
Conditions
Major Depressive Disorder, Suicidal Ideation
Interventions
Trier Social Stress Test
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Variability in Adrenergic Response

NCT00838695
View directory record Official record
Conditions
Vascular Reaction to Medications
Interventions
Phenylephrine
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 40 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 26, 2018 · Synced Oct 2, 2026, 2:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls

NCT03450135
View directory record Official record
Conditions
Adolescent Development, Stress, Emotional Disturbances
Interventions
Trier Social Stress Test, Emotional go/no-go task
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 14 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 2, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adverse Adolescent Pathways to Substance Use

NCT06977178
View directory record Official record
Conditions
Anxiety, Adolescent Development, Substance Use
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 14 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers

NCT04109599
View directory record Official record
Conditions
Opioid Misuse
Interventions
PlaySmart, PlaySmart Storyline, Play Smart Mini-Game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 19 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System

NCT04207333
View directory record Official record
Conditions
Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change, Cerebrovascular Insufficiency
Interventions
Mental Arithmetic Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 59 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Results available

Multi-Component Intervention to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

NCT04549259
View directory record Official record
Conditions
HIV
Interventions
Group-Based Social Support, HIV Stigma Reduction, Strengths-Based Case Management (SBCM), Personalized Technology Detailing
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 2, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adolescent Stress and Substance Intervention Subsequent to Trauma

NCT07197476
View directory record Official record
Conditions
PTSD, Substance Use Disorder (SUD), Acute Stress Disorder
Interventions
ASSIST Video Intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional

Support for People Undergoing Chemotherapy

NCT00740038
View directory record Official record
Conditions
Quality of Life, Cancer
Interventions
Stress Management training, Exercise Training, Usual care, Combined stress management and exercise training
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 2, 2026, 2:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

High Resolution Phenotyping in Healthy Humans

NCT00943774
View directory record Official record
Conditions
Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability, Arterial Catecholamines
Interventions
Physiological maneuvers
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 2, 2026, 2:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mental Stress & Diesel Exhaust on Cardiovascular Health

NCT03467997
View directory record Official record
Conditions
Blood Pressure, Inflammation, Catecholamines
Interventions
Trier social stress test, Diesel exhaust
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
22 Years to 49 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cortisol and Food Insecurity

NCT05191030
View directory record Official record
Conditions
Food Insecurity
Interventions
High-Stress Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
453 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Depression, Aging, Stress and Heart Health Study

NCT05570721
View directory record Official record
Conditions
Menopause, Depression, Heart Disease in Women, Stress
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
44 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Phase 2 Interventional

Low-intensity Stepped Care for Internalizing Distress

NCT05441111
View directory record Official record
Conditions
Depression, Anxiety, Emotion Regulation
Interventions
Common Elements Toolbox, Doing What Matters in Times of Stress: An Illustrated Guide, Guided self-help
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 2, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional

Family Spirit Strengths

NCT05836090
View directory record Official record
Conditions
Depressive Symptoms, Anxiety Disorders and Symptoms, Substance Use, Mental Health Issue
Interventions
Family Spirit Strengths (FSS), Family Spirit Nurture
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years and older · Female only
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Chinle, Arizona • Pokagon, Michigan • Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Completed No phase listed Observational

Veteran Health Study

NCT01175629
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Diabetes, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Male only
Enrollment
7,568 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiac Autonomic Function in Women with Microvascular Coronary Dysfunction

NCT01568177
View directory record Official record
Conditions
Microvascular Coronary Dysfunction
Interventions
Mental Stress Testing, Peripheral Arterial Tonometry (PAT) Testing, Heart Rate Variability (HRV), RESPeRATE Breathing Trial, SPECT cardiac scan with 123I-mIBG and Myoview
Behavioral · Other · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protecting Native Families From COVID-19

NCT04765475
View directory record Official record
Conditions
COVID-19
Interventions
Motivational Interviewing, COVID-19 Symptom Monitoring System, Motivational Interviewing and COVID-19 Symptom Monitoring System, Supportive Services
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Oct 2, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stress Trajectories and Anhedonia in Adolescence Research Study

NCT07040449
View directory record Official record
Conditions
Anhedonia, Stress Response, Adolescent Development
Interventions
Montreal Imaging Stress Task, Trier Social Stress Test for Children
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 15 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)

NCT04813198
View directory record Official record
Conditions
Group Meetings
Interventions
TIPSTART
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 34 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 2, 2026, 2:31 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Mindfulness-Based Stress Reduction to Improve Well-being in Black Adult Cancer Survivors, Community Faith-based Mindfulness Ministry

NCT06767475
View directory record Official record
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Educational Intervention, Discussion, Mindfulness Relaxation, Interview, Questionnaire Administration
Other · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 2, 2026, 2:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention

NCT03441997
View directory record Official record
Conditions
Fibromyalgia
Interventions
Mind-body exercise, Light mobility exercises
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 4, 2019 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress, Salt Excretion, and Nighttime Blood Pressure

NCT03636490
View directory record Official record
Conditions
Blood Pressure, Psychological Stress
Interventions
Psychological Stress Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2025 · Synced Oct 2, 2026, 2:31 AM EDT
Completed Not applicable Interventional Results available

Feasibility of Remote Tai Chi

NCT05693805
View directory record Official record
Conditions
PTSD, Pain, Chronic
Interventions
Tai Chi, Wellness program
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 2, 2026, 2:31 AM EDT