- Conditions
- Tobacco Use, Cigarette Use
- Interventions
- Very Low Nicotine Cigarette, Reduced nicotine regulatory environment, Restriction on characterizing flavors in combustible nicotine products, Restriction on characterizing flavors in noncombustible nicotine products
- Drug · Behavioral
- Lead sponsor
- Mikhail N Koffarnus
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 473 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–9
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- Conditions
- Cigarette Smoking, Smoking Behaviors
- Interventions
- Very low nicotine cigarette: menthol, Very low nicotine cigarette: non-mentol
- Other
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 34 Years
- Enrollment
- 171 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Tobacco Use
- Interventions
- Non-Menthol Very Low Nicotine Cigarettes, Menthol Very Low Nicotine Cigarettes, Subject's UB non-mentholated filtered cigarettes, Subject's UB mentholated filtered cigarettes
- Other
- Lead sponsor
- 22nd Century Group, Inc.
- Industry
- Eligibility
- 26 Years to 65 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Lincoln, Nebraska • High Point, North Carolina
- Conditions
- Tobacco Use
- Interventions
- VLN cigarettes (A), Usual Brand Cigarettes (B), Nicotine gum (C)
- Other · Drug
- Lead sponsor
- 22nd Century Group, Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Tobacco Use
- Interventions
- VLN menthol cigarettes (A), Usual Brand Menthol Cigarettes (B), Nicotine gum (C)
- Other · Drug
- Lead sponsor
- 22nd Century Group, Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Chronic Pain, Tobacco Use, Opioid Substitution Treatment
- Interventions
- Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Tobacco Smoking, Nicotine Dependence
- Interventions
- Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Drug
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 799 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 6
- States / cities
- San Francisco, California • Minneapolis, Minnesota • Durham, North Carolina + 3 more
- Conditions
- Nicotine Dependence
- Interventions
- Standard treatment, Standard treatment+practice quitting, Very low nicotine cigarettes
- Behavioral · Drug
- Lead sponsor
- Rutgers University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 93 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- New Brunswick, New Jersey
- Conditions
- Chronic Pain, Smoking, Cigarette
- Interventions
- SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Durham, North Carolina