- Conditions
- Smoking (Tobacco) Addiction
- Interventions
- Menthol cigarettes substitutes, Usual brand menthol cigarettes and substitutes, Menthol cigarettes substitutes and menthol cigarettes
- Behavioral
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
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Showing 1–24
of 49
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Tobacco Use
- Interventions
- Cigarette Brand Switching
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Smoking
- Interventions
- Minimally Ventilated non-menthol cigarettes, Ventilated non-menthol cigarettes
- Other
- Lead sponsor
- Masonic Cancer Center, University of Minnesota
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Nicotine Dependence
- Interventions
- Reduced Nicotine Content- Non Menthol, Reduced Nicotine Content- Menthol, Conventional Nicotine Content- Menthol, Conventional Nicotine Content- Non Menthol
- Other
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 381 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2020
- U.S. locations
- 2
- States / cities
- Farmington, Connecticut • Hartford, Connecticut
- Conditions
- Tobacco Use Disorder
- Interventions
- Menthol ban on cigarettes, Menthol ban on cigarettes and e-cigarettes, No menthol ban
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Smoking, Tobacco Use
- Interventions
- Product A, Product B, Product C, Product D, Product E, Product F, Product G, Product N
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Knoxville, Tennessee
- Conditions
- Smoking, Tobacco
- Interventions
- P1213416, P1213422, P1213716, P1213722, P1211216, P1211222, P1213616, P1213622, P1213816, P1213822, P1211916, P1211922
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 1,845 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 12
- States / cities
- Phoenix, Arizona • Fort Lauderdale, Florida • Orlando, Florida + 9 more
- Conditions
- Smoking Prevention and Control
- Interventions
- Non-Menthol Cigarettes, Tobacco Flavored E-cigarettes, Menthol Cigarettes, Menthol Flavored E-cigarettes
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Tobacco Use
- Interventions
- Non-Menthol Very Low Nicotine Cigarettes, Menthol Very Low Nicotine Cigarettes, Subject's UB non-mentholated filtered cigarettes, Subject's UB mentholated filtered cigarettes
- Other
- Lead sponsor
- 22nd Century Group, Inc.
- Industry
- Eligibility
- 26 Years to 65 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Lincoln, Nebraska • High Point, North Carolina
- Conditions
- Chronic Pain, Smoking, Cigarette
- Interventions
- SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Nicotine Dependence
- Interventions
- Reduced Nicotine Non-Menthol (RNC), Reduced Nicotine Menthol (RNC-Men), Conventional Nicotine Non-Menthol (CN)
- Other
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years to 45 Years · Male only
- Enrollment
- 118 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 2
- States / cities
- Farmington, Connecticut • Hartford, Connecticut
- Conditions
- Smoking Behaviors
- Interventions
- Intervention ads, Control ads
- Behavioral
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 1,236 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Smoking, Tobacco
- Interventions
- P2613422, P2611222, P2615522, P2615122, P2615422
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 1,280 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 7
- States / cities
- Maitland, Florida • Atlanta, Georgia • St Louis, Missouri + 4 more
- Conditions
- Tobacco Use, Smoking, Smoking, Tobacco
- Interventions
- Lung Permeability Assessment
- Procedure
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 30 Years to 50 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Lincoln, Nebraska
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking
- Interventions
- JUUL ENDS 5% Virginia Tobacco, JUUL 3% Virginia Tobacco ENDS, JUUL 5% Mint ENDS, JUUL 3% Mint ENDS, JUUL 5% Menthol ENDS, JUUL 3% Menthol ENDS, JUUL 5% Mango ENDS, JUUL 3% Mango ENDS, US Cigarette, Non-menthol - Marlboro Gold King Size, US Cigarette, Menthol - Newport King Size
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 3
- States / cities
- Secaucus, New Jersey • Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Tobacco Use
- Interventions
- Ploom HTP Menthol HTS; MX3 (681), Ploom HTP Tobacco HTS; R8 (120), Smoking Abstinence (menthol), Smoking Abstinence (non-menthol)
- Other
- Lead sponsor
- Altria Client Services LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 921 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 8
- States / cities
- Bentonville, Arkansas • Rogers, Arkansas • Overland Park, Kansas + 5 more
- Conditions
- Tobacco Smoking, Tobacco Use
- Interventions
- Not listed
- Lead sponsor
- Altria Client Services LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Stockbridge, Georgia
- Conditions
- Tobacco Use
- Interventions
- Flavor Ban, Menthol Ban, All flavored and mentholated products available
- Other
- Lead sponsor
- RAND
- Other
- Eligibility
- 11 Years to 20 Years
- Enrollment
- 267 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Nicotine Dependence
- Interventions
- nicotine, menthol
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 2
- States / cities
- West Haven, Connecticut
- Conditions
- Tobacco Use, Smoking, Tobacco Smoking
- Interventions
- Marlboro Gold Box, Newport Box, Non-combusted cigarette variant 42001401, Non-combusted cigarette variant 42001399, Non-combusted cigarette variant 40007386, Non-combusted cigarette variant 42001402
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Stockbridge, Georgia
- Conditions
- Cigarette, Smoking Behaviors, Cigarette Smoking Behavior
- Interventions
- Mentholated cigarette sampling, Hypothetical Policy Scenarios, Subjective value assessment
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Tobacco Use
- Interventions
- Cigarette Brand Switching, E-cigarette Flavor
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Interventions
- Product A, Product B, Product C, Product D, Product N, Product E
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Knoxville, Tennessee
- Conditions
- Nicotine Use Disorder
- Interventions
- E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut