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ClinicalTrials.gov public records Last synced Oct 11, 2026, 8:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 310 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Mesenchymal Stem Cell Clear all

Conditions: Graft-Versus-Host Disease
Interventions: Prochymal®; Drug
Lead sponsor: Mesoblast, Inc.; Industry
Eligibility: 18 Years to 70 Years
U.S. locations: 3
States / cities: Beech Grove, Indiana • Boston, Massachusetts • New York, New York

Conditions: Knee Pain Chronic, Osteo Arthritis Knee
Interventions: HB-adMSC; Biological
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: Not listed
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Crohn's Disease
Interventions: Prochymal®, Placebo; Drug
Lead sponsor: Mesoblast, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 47
States / cities: Los Angeles, California • San Francisco, California • Wheat Ridge, Colorado + 38 more

Conditions: Amyotrophic Lateral Sclerosis
Interventions: HB-adMSCs; Biological
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: Not listed
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Heart Failure, Systolic
Interventions: CardiALLO™ Human Allogenic Culture-expanded Bone marrow-derived Mesenchymal Stem Cells (hMSCs), Diagnostic Catheterization; Combination Product · Diagnostic Test
Lead sponsor: BioCardia, Inc.; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Mesenchymal Stem Cells; Biological
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Rheumatoid Arthritis
Interventions: HB-adMSCs; Biological
Lead sponsor: Hope Biosciences LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Pasadena, Texas

Conditions: Lung Transplant Reject, Bronchiolitis Obliterans
Interventions: Mesenchymal stem cell 0.5, Mesenchymal stem cell 1.0; Biological
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Amyotrophic Lateral Sclerosis (ALS), Amyotrophic Lateral Sclerosis
Interventions: Debamestrocel - MSC-NTF (NurOwn), Placebo; Biological
Lead sponsor: Brainstorm-Cell Therapeutics; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 15
States / cities: Phoenix, Arizona • La Jolla, California • Los Angeles, California + 11 more

Conditions: Recovery Following Partial Medial Meniscectomy
Interventions: Mesenchymal Stem Cells, Hyaluronan; Drug
Lead sponsor: Mesoblast International Sàrl; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 8
States / cities: Los Angeles, California • Vero Beach, Florida • Chicago, Illinois + 5 more

Conditions: Knee Osteoarthritis
Interventions: BMAC injection, PRP injection, Gel-One® hyaluronate injection; Biological · Device
Lead sponsor: OhioHealth; Other
Eligibility: 40 Years to 70 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cognitive Dysfunction
Interventions: adMSC; Biological
Lead sponsor: Paul E Schulz; Other
Eligibility: 60 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Head and Neck Cancer, Xerostomia
Interventions: MSC; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 90 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Endothelial Dysfunction, Metabolic Syndrome, Chronic Inflammation
Interventions: UCMSCs, BMMSCs, Placebo; Biological · Other
Lead sponsor: Joshua M Hare; Other
Eligibility: 21 Years to 95 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Cartilage Defect
Interventions: REcycled CartiLage Auto/Allo IMplantation; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 50 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Degenerative Disc Disease
Interventions: Rexlemestrocel-L, Rexlemestrocel-L + HA Mixture, Placebo; Drug
Lead sponsor: Mesoblast, Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 404 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 47
States / cities: Birmingham, Alabama • Huntsville, Alabama • Scottsdale, Arizona + 42 more

Conditions: Full Thickness Rotator Cuff Tear
Interventions: Mesenchymal stem cell augmentation in rotator cuff repair, Standard arthroscopic rotator cuff repair; Biological · Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Laser Therapy, Exosomes
Interventions: 1064-nm Nd:YAG Laser Treatment, Topical Umbilical Cord-Derived Exosomes (UC-MSC Exosomes); Device · Biological
Lead sponsor: Laser Beamer Skincare; Other
Eligibility: 45 Years to 70 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Wichita, Kansas

Conditions: Alveolar Ridge Augmentation
Interventions: BioMend Extend, Modified BioMend Extend; Other
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Ischemic Stroke
Interventions: bone marrow-derived mesenchymal stem cells, Placebo; Biological · Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Orange, California

Conditions: Amyotrophic Lateral Sclerosis
Interventions: autologous mesenchymal stem cells; Biological
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Covid19, ARDS
Interventions: COVI-MSC, Placebo; Drug
Lead sponsor: Sorrento Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Fresno, California

Conditions: Duchenne Muscular Dystrophy
Interventions: Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC); Biological
Lead sponsor: MED Institute Inc.; Industry
Eligibility: 5 Years to 10 Years · Male only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: Dallas, Texas • Flower Mound, Texas

Conditions: Acute Respiratory Distress Syndrome, ARDS (Moderate or Severe), COVID-19 Pneumonia
Interventions: Mesenchymal stromal cells, Placebo; Biological · Other
Lead sponsor: Masonic Cancer Center, University of Minnesota; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Pittsburgh, Pennsylvania

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Prochymal® Expanded Access for Adults Who Have Failed Steroid Treatment for Acute Graft Versus Host Disease (GVHD)

Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.

Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-resistant Moderate-to-severe Crohn's Disease

Individual Patient Expanded Access IND of Autologous HBadMSCs for the Treatment of Amyotrophic Lateral Sclerosis

Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells

Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)

Phase 1/2a Clinical Trial to Assess the Safety of HB-adMSCs for the Treatment of Rheumatoid Arthritis

Mesenchymal Stem Cell Therapy for Lung Rejection

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

A Phase I/II Study of Chondrogen Delivered by Intra-Articular Injection Following Meniscectomy

Investigation of Mesenchymal Stem Cell Therapy for the Treatment of Osteoarthritis of the Knee

Stem Cell Therapy for Early Alzheimer's Disease

Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy

Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression.

REcycled CartiLage Auto/Allo IMplantation

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain

Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair

Enhancing Skin Rejuvenation Using Laser and Exosomes

Enhancing Guided Bone Regeneration by Modifying a Resorbable Membrane

Safety of Escalating Doses of Intravenous Bone Marrow-Derived Mesenchymal Stem Cells in Patients With a New Ischemic Stroke

Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS)

Study of Intravenous Administration of Allogeneic Adipose-Derived Mesenchymal Stem Cells for COVID-19-Induced Acute Respiratory Distress

Study of UC-MSC in DMD Patients

Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)