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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:44 PM EDT

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Showing 193–216 of 300 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

NCT06444347
Conditions
Hiatal Hernia
Interventions
Biosynthetic Mesh, Hiatal Hernia Repair
Device · Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
6
States / cities
Los Angeles, California • New Orleans, Louisiana • St Louis, Missouri + 1 more
Conditions
Breast Cancer, Radiation, Breast Reconstruction, Synthetic Mesh
Interventions
TiLoop Bra mesh in expander-implant breast reconstrution, sub-pectoral expander-implant breast reconstruction
Procedure
Lead sponsor
Tianjin Medical University Cancer Institute and Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Urinary Incontinence, Stress
Interventions
The AMS Male Transobturator Sling System, AdVance Male Sling
Device
Lead sponsor
American Medical Systems
Industry
Eligibility
40 Years and older · Male only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
10
States / cities
Los Angeles, California • Denver, Colorado • Ann Arbor, Michigan + 7 more
Conditions
Chronic Hepatitis C Virus
Interventions
LDV/SOF, RBV
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
53
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 50 more
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound

NCT03829618
Conditions
Bronchiectasis Adult, Mediastinal Lymphadenopathy, Pneumonia, Chest--Diseases, Infiltrates, Bronchopulmonary Disease, Cancer, Lung
Interventions
Topical lidocaine, Nebuliser solution, Nebuliser Suspension
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Completed No phase listed Observational

The Biologic Basis of Hernia Formation

NCT01099033
Conditions
Hiatal Hernia, Paraesophageal Hernia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle® Flat Mesh
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Dearborn, Michigan
Conditions
Joint Disease, Arthropathy
Interventions
Zipper surgical skin closure, Monocryl + Dermabond, Polyester mesh + Dermabond
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Pelvic Organ Prolapse
Interventions
Elevate Mesh, Anterior Colporrhaphy
Procedure
Lead sponsor
Emanuel Trabuco
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
Roseville, California • Santa Clara, California • Stanford, California + 2 more
Terminated Phase 4 Interventional Results available

Hernia Repair in Multiply Morbid Patients

NCT00930787
Conditions
Ventral Hernia
Interventions
Strattice Reconstructive Tissue Matrix (Hernia Repair), Proceed Surgical Mesh (Hernia repair)
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
13
States / cities
New Orleans, Louisiana • Baltimore, Maryland • West Roxbury, Massachusetts + 8 more
Conditions
Ventral Incisional Hernia
Interventions
GORE® BIO-A® Tissue Reinforcement
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Indianapolis, Indiana • St Louis, Missouri + 5 more
Conditions
Hypoxemic Respiratory Failure, Airway Obstruction
Interventions
nebulizer via in-line drug delivery maintaining high-flow nasal cannula oxygen, standard jet nebulization (SJN) with face mask
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Conditions
Inguinal Hernia
Interventions
Not listed
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Grand Blanc, Michigan
Completed Not applicable Interventional Results available

Safety Study of MotifMESH (cPTFE) in Abdominal Surgery

NCT01364233
Conditions
Hernia
Interventions
MotifMESH
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM

NCT03283982
Conditions
Ventral Hernia
Interventions
Robotic Ventral Hernia Repair with IPOM, Laparoscopic Ventral Hernia Repair with IPOM
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational Results available

Pelvic Floor Repair Systems for Prolapse Repair

NCT00638235
Conditions
Pelvic Organ Prolapse
Interventions
AMS Apogee™ with IntePro, AMS Apogee™ with Intexen LP, AMS Perigee™ with IntePro, AMS Perigee™ with IntePro Lite, AMS Apogee™ with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntXen LP, AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 1, For Study Use Only), AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 2)
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
725 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
17
States / cities
Downey, California • Wellington, Florida • Alpharetta, Georgia + 12 more
Conditions
Wound Complication
Interventions
Biologic Mesh, Small Bites, Large Bites
Device · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Houston, Texas
Conditions
Postoperative Restriction, Midurethral Sling, Mesh, Stress Urinary Incontinence
Interventions
Limited Restrictions, Standard Restrictions
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Subjects Requiring Revision Breast Augmentation Surgery
Interventions
SERI® Surgical Scaffold
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
5
States / cities
La Jolla, California • San Francisco, California • Troy, Michigan + 2 more
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparative Study of Biologic Mesh Versus Repair With Component Separation.

NCT01295125
Conditions
Ventral Hernia
Interventions
XenMATRIX mesh, Open abdominal ventral hernia repair
Device · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Hernia, Ventral
Interventions
Open mesh repair of ventral incisional hernia, Laparoscopic mesh repair of ventral incisional hernia
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Not applicable Interventional

Platelet Rich Plasma in Hiatal Hernia Repair

NCT05023174
Conditions
Hiatal Hernia Large, Reflux, Gastroesophageal
Interventions
Hiatal Hernia Repair with Platelet Rich Plasma, Hiatal Hernia Repair without Platelet Rich Plasma
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Newport Beach, California
Conditions
Paroxysmal Atrial Fibrillation
Interventions
HD Mesh Ablation System, Anti-arrhythmic drugs
Device · Drug
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
13
States / cities
San Diego, California • Aurora, Colorado • Gainesville, Florida + 9 more