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ClinicalTrials.gov public records Last synced Sep 17, 2026, 9:09 AM EDT

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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Ventral Hernia, Umbilical Hernia, Epigastric Hernia
Interventions
Ventral Hernia Repair
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Paraesophageal Hernia
Interventions
Matristem, Control
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Ventral Incisional Hernia
Interventions
Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh

NCT04779918
Conditions
Hernia, Ventral, Hernia, Inguinal
Interventions
OviTex Reinforced Tissue Matrix
Device
Lead sponsor
Tela Bio Inc
Industry
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2029
U.S. locations
10
States / cities
Mobile, Alabama • Denver, Colorado • Destin, Florida + 7 more
Conditions
Ventral Hernia
Interventions
robotic-assisted ventral hernia repair
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
69 participants
Timeline
2021 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Not listed Phase 4 Interventional Accepts healthy volunteers

Biologic Versus Synthetic Mesh for Treatment of Paraesophageal Hernia

NCT02242526
Conditions
Hiatal Hernia
Interventions
Parietex™ Composite Hiatal Mesh, North Haven, CT, Biodesign™ Surgisis® Graft, Cook Medical, Bloomington
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 80 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Ventral Hernia
Interventions
Phasix mesh implant
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Ventral Hernia, Adhesions
Interventions
Clinically-Indicated Abdominal Re-Exploration Surgery
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
6
States / cities
Phoenix, Arizona • San Diego, California • Springfield, Massachusetts + 3 more
Conditions
Paraesophageal Hernia, GERD
Interventions
OviTex Mesh, Pledgeted sutures
Device · Other
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Results available

Biologic Mesh Versus Synthetic Mesh in Repair of Ventral Hernias

NCT02451176
Conditions
Ventral Hernia
Interventions
Davol Bard Soft Mesh synthetic, LifeCell Strattice Reconstructive Tissue Biologic
Device
Lead sponsor
Michael Rosen
Other
Eligibility
21 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Greenville, South Carolina + 1 more
Conditions
Hernia, Ventral
Interventions
Open mesh repair of ventral incisional hernia, Laparoscopic mesh repair of ventral incisional hernia
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Hernia Repair With Compartment Syndrome
Interventions
Flex HD, Strattice
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Ventral Hernia Repair
Interventions
Gemcitabine/ clindamycin, Normal saline
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Morbid Obesity, Weight Loss, Complex Incisional Hernias
Interventions
Endoscopic Gastric Plication
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Francisco, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

NCT06444347
Conditions
Hiatal Hernia
Interventions
Biosynthetic Mesh, Hiatal Hernia Repair
Device · Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
6
States / cities
Los Angeles, California • New Orleans, Louisiana • St Louis, Missouri + 1 more
Conditions
Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery, Anxiety
Interventions
Patient-Chosen Music, Placebo
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Ventral Hernia Repair
Interventions
Silk surgical mesh
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Chronic Groin Pain, Hernia, Inguinal
Interventions
Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
Procedure
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
Interventions
surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Watchful waiting with supportive care
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Hernia, Inguinal
Interventions
Biomerix Revive™ (surgical mesh for inguinal hernia repair)
Device
Lead sponsor
Biomerix
Industry
Eligibility
19 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Omaha, Nebraska • Houston, Texas
Conditions
Ventral Incisional Hernia
Interventions
GORE® BIO-A® Tissue Reinforcement
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Indianapolis, Indiana • St Louis, Missouri + 5 more
Conditions
Ventral Hernia
Interventions
Strattice Arm, Bio-A Arm
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Hernia
Interventions
ECLIPSIUM® System, Resorbable tacks (AbsorbaTack/SorbaFix)
Device
Lead sponsor
Tissium
Industry
Eligibility
22 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
12
States / cities
Loma Linda, California • Gainesville, Florida • Chicago, Illinois + 9 more
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina