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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Message Framing Text Message Clear all
Completed Not applicable Interventional

Scaling Up: A Multi-Site Trial of e-SBI for Alcohol Use in Pregnancy

NCT04332172
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Fetal Alcohol Effect
Interventions
General information, Baseline brief intervention, Remote online booster sessions, SMS
Other · Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Reinforcement Learning in Diabetes Mellitus Trial

NCT04473326
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Medication Adherence
Interventions
Reinforcement Learning
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 84 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Safer Food Allergy Management for Adolescents

NCT03284372
View directory record Official record
Conditions
Food Allergy, Adherence, Medication
Interventions
Text Message Only, Text message + Incentive 1
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
15 Years to 19 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Way to Be Active V (Framing vs. Forgiveness)

NCT02030132
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Feedback compared to 75th percentile, Forgiveness, Financial Incentive, Daily Feedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

NCT06644664
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

COVID-19 Vaccine Text Outreach

NCT04834726
View directory record Official record
Conditions
Covid19
Interventions
Opt-In (Call-Back), Opt-in (In-Bound), Standard Message, Clinician Endorsement, Scarcity, Opt-Out Framing, Phone Call
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older
Enrollment
19,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VEText Message Framing and Covid-19 Vaccine Uptake Among at Risk Veterans

NCT04805931
View directory record Official record
Conditions
Covid19, Vaccine Refusal
Interventions
Behavioral economics
Behavioral
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years and older
Enrollment
4,311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination

NCT03856437
View directory record Official record
Conditions
Cervical Cancer, Anal Cancer, Penile Cancer
Interventions
HPV vaccination messages
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 99 Years
Enrollment
1,170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 2, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional

Penn Medicine Food Market Study

NCT06283394
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Storefront Choice Architecture, Fresh Funds, Loss Framing
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 70 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 2, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional

Kaiser Colorado Flu Nudge

NCT07372950
View directory record Official record
Conditions
Influenza, Vaccination
Interventions
Behavioral economics framed test messaging
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
6 Months and older
Enrollment
100,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Information Provision and Consistency Framing to Increase COVID-19 Booster Uptake

NCT05586178
View directory record Official record
Conditions
COVID-19, Vaccines
Interventions
Reminder that facilitates action, Consistency framing, Information provision about the uniqueness of the bivalent booster, Information provision about bivalent booster eligibility, Information provision about the severity of COVID-19 symptoms
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
177,720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Way to Be Active III (Framing Incentives)

NCT02030119
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Financial Incentives, Daily feedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2017 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving

NCT05469477
View directory record Official record
Conditions
Distracted Driving, Impaired Driving, Driving Behaviors
Interventions
Persuasive education, WOOP (aka, mental contrasting with implementation intentions., Wish, Outcome, Obstacle, Plan), Customized Habit Tips, Raffle Financial Incentive, Shared Pot Financial Incentive, Weekly SMS Support text, Weekly SMS Encouragement
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Does Framing and Humor Improve the Effectiveness of Messages About COVID-19 Vaccine

NCT05085613
View directory record Official record
Conditions
Beliefs
Interventions
Corrective message framing and humor
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
21 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization

NCT07569250
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Personalized Text Message, Screening Concerns Text Message, Message Framing Text Message, Autonomy Support Outreach, Impediments Support Outreach, Live Support Outreach, Data Reporting and Visualization System Tools
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 75 Years
Enrollment
7,220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
4
States / cities
Boston, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
View directory record Official record
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

COVID-19 Booster Readiness Survey

NCT05529030
View directory record Official record
Conditions
Vaccination Refusal
Interventions
Salience of Omicron variant, Self-protection message, Other-protection message
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
12,036 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional

SupportBP 2.0:Behavioral Science and Enrollment in Remote Monitoring for Hypertension Management

NCT04714398
View directory record Official record
Conditions
Hypertension
Interventions
Opt-In Recruitment, Opt-Out Recruitment
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
425 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Health Sleep and Growth Study 2

NCT03426644
View directory record Official record
Conditions
Childhood Sleep Promotion
Interventions
Mobile Sleep and Growth Study
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 12 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

CBT Texts for PTSD & Hazardous Drinking (Project Better)

NCT05372042
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use
Interventions
CBT Text Messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting Access and Knowledge of Earned Income Tax Credit (EITC) Utilization and Policies

NCT06146621
View directory record Official record
Conditions
Mental Health Issue, Food Security, Well-being
Interventions
Low-touch text messaging, Personal tax filing support, Information about free tax-filing support, Financial assistance
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Framing on Medication Beliefs, Intentions to Take Medication, Adherence, and Asthma Control

NCT06033313
View directory record Official record
Conditions
Asthma
Interventions
Negatively Framed text messages, Positively Framed text messages
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 29 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 2, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing Promising Behavioral Economic Interventions to Promote Enrollment Diversity in Cardiovascular Cohort Studies

NCT05827718
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Method of Contact, Source of Contact, Framing Method (Appeal to Altruism or Social Proof, Incentive Structure
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26,242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 2, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Nudging Parental Actions for Youth Suicide Prevention

NCT07383714
View directory record Official record
Conditions
Suicide, Suicide Attempt
Interventions
Text-messaging for safety reminders, Text-messaging with safety reminders and risk framing
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
13 Years to 17 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 2, 2026, 2:09 PM EDT