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Showing 1–24 of 707 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Metabolic Diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin

NCT03289832
View directory record Official record
Conditions
Healthy Adults
Interventions
Crucera-SGS, Meriva 500-SF
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PREDICT 2: Personalized Responses to Dietary Composition Trial 2

NCT03983733
View directory record Official record
Conditions
Diabetes, Heart Diseases, Diet Habit, Diet Modification, Microbial Colonization, Healthy, Obesity, Metabolism
Interventions
Dietary Intervention
Other
Lead sponsor
Zoe Global Limited
Other
Eligibility
18 Years to 70 Years
Enrollment
1,139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Low Starch Dietary Education Program vs. Traditional Treatment for PCOS

NCT03916263
View directory record Official record
Conditions
PCOS, Diet Modification, Metabolism, Nutrition Disorders
Interventions
Metformin, One-On-One Dietary Instruction, Video Dietary Instruction
Drug · Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Low-Fat Vegan Diet Versus a Mediterranean Diet on Body Weight

NCT03698955
View directory record Official record
Conditions
Overweight, Obesity, Insulin Resistance
Interventions
Plant-based diet, Mediterranean Diet
Other
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 8, 2026, 2:23 AM EDT
Not listed Not applicable Interventional

C15:0 Supplementation in Young Adults at Risk for Metabolic Syndrome

NCT04947176
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Supplement, Placebo
Dietary Supplement · Other
Lead sponsor
Jeffrey B. Schwimmer, MD
Other
Eligibility
18 Years to 25 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity in the Treatment of Obesity

NCT00615238
View directory record Official record
Conditions
Obesity
Interventions
Diet plus continuous bouts, Diet plus short bouts, Diet plus moderate lifestyle activity
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Phase 2 Interventional Results available

Reduced Carbohydrate Versus Fat in Obese Subjects

NCT00846040
View directory record Official record
Conditions
Obesity
Interventions
Reduced fat diet, Reduced carbohydrate diet, Drug: f-18 fallypride, fMRI, PET
Other · Drug · Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a PUFA-rich Diet on Acute Metabolic and Inflammatory High-Fat Meal Responses

NCT02246933
View directory record Official record
Conditions
Inflammation, Obesity
Interventions
PUFA Diet, Control Diet
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Precision Nutrition Impact on Health-Related Behavior Change

NCT04959318
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Professional nutrition counseling, No professional nutrition counseling
Other
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 45 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

NCT04990817
View directory record Official record
Conditions
Elevated Triglycerides, Hypertriglyceridemia
Interventions
Average American Diet With SoFAS Replaced With Avocado, Average American Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 8, 2026, 2:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)

NCT02959762
View directory record Official record
Conditions
Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases, Hyperlipidemia, Hyperglycemia, Cardiovascular Diseases
Interventions
Placebo-Control, Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Re-energize With Nutrition, Exercise and Weight Loss

NCT00712127
View directory record Official record
Conditions
Obesity
Interventions
Diet and Exercise, Diet and Exercise-Delayed
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Novel Method to Study in Vivo Fatty Acid Metabolism Using Stable Isotope Labeled Fatty Acids in Humans

NCT02312492
View directory record Official record
Conditions
Dyslipidemia
Interventions
Oleic Diet, Palmitic Diet, Stearic Diet
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 85 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 8, 2026, 2:23 AM EDT
Active, not recruiting Not applicable Interventional

Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain Tumors

NCT01535911
View directory record Official record
Conditions
Glioblastoma
Interventions
Energy restricted Ketogenic Diet (ERKD) (Metabolic Nutritional Therapy)
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Effects of a Thermogenic Ready-to-drink Beverage

NCT05194475
View directory record Official record
Conditions
Metabolic Rate, Metabolism
Interventions
Thermogenic Ready-to-drink Beverage, Placebo Ready-to-drink Beverage
Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Sep 8, 2026, 2:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

NCT07546409
View directory record Official record
Conditions
Prediabetes, Healthy (Controls)
Interventions
Ketone Monoester (KE), Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals

NCT01510665
View directory record Official record
Conditions
Gestational Diabetes, Obesity
Interventions
Magnesium citrate, Placebo, Dietary modification
Dietary Supplement · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation

NCT02955264
View directory record Official record
Conditions
Congenital Disorders of Glycosylation
Interventions
D-Galactose
Dietary Supplement
Lead sponsor
Tulane University
Other
Eligibility
Up to 21 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Sep 8, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Translation of Pritikin Program to the Community

NCT03929198
View directory record Official record
Conditions
Metabolic Syndrome, Obesity, Weight Loss, Hypertension, Hypercholesterolemia, Hypertriglyceridemia
Interventions
Healthy Lifestyle
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Sep 8, 2026, 2:23 AM EDT
Terminated Not applicable Interventional

Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep

NCT05413928
View directory record Official record
Conditions
PreDiabetes, Type 2 Diabetes, Healthy
Interventions
Time Restrictive Eating- late, Time Restrictive Eating- early, Time Restrictive Eating- early with early caloric intake, Macronutrient-controlled meals
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 8, 2026, 2:23 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Bioavailability of Vitamin D(25(OH)D) and Omega-3 Fatty Acid (DHA) Enhanced Chicken

NCT05248737
View directory record Official record
Conditions
Nutrition, Healthy
Interventions
DHA/EPA fortified chicken plus Placebo, non-25(OH)D fortified chicken/eggs plus vitamin D3 supplement, non-DHA bio-enhanced chicken plus supplement DHA Omega-3, 25(OH)D bioenhanced chicken and eggs plus placebo, Dietary Supplement: DHA/EPA fortified eggs plus Placebo, non-DHA bio-enhanced eggs plus supplement DHA Omega-3, non-25(OH)D fortified chicken/eggs plus placebo
Dietary Supplement · Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 35 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 8, 2026, 2:23 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Novel Fiber on Glucose Homeostasis in Individuals at Risk for Diabetes

NCT00820807
View directory record Official record
Conditions
Insulin Resistance
Interventions
Novel dietary fiber, Placebo
Other
Lead sponsor
Cargill
Industry
Eligibility
30 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 16, 2011 · Synced Sep 8, 2026, 2:23 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity

NCT05912621
View directory record Official record
Conditions
Obesity, Overweight and Obesity, Overweight
Interventions
Tirzepatide
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 8, 2026, 2:23 AM EDT