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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:16 AM EDT

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Showing 1–24 of 1,014 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome Clear all
Completed Phase 3 Interventional Results available

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

NCT03959241
View directory record Official record
Conditions
Acute Leukemia, Chronic Myelogenous Leukemia (CML), Myelodysplasia, Lymphoma
Interventions
Mobilized Peripheral Blood Stem Cell graft with Tacrolimus/Methotrexate, Tacrolimus, Methotrexate, Mobilized Peripheral Blood Stem Cell graft with Tacrolimus/Mycophenolate Mofetil/Post-Transplant Cyclophosphamide, Mycophenolate Mofetil, Cyclophosphamide
Procedure · Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
431 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
39
States / cities
Birmingham, Alabama • Duarte, California • San Francisco, California + 30 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Phase 1 Interventional

Antibiotics, Gastric Bypass, and the Microbiome

NCT05367479
View directory record Official record
Conditions
Obesity, Morbid, Hypertension, Bariatric Surgery Candidate
Interventions
Antibiotic
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Strawberry Consumption on the Microbiome

NCT04217122
View directory record Official record
Conditions
Microbiome
Interventions
strawberry powder, placebo powder
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2020 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Results available

Very Low Birth Weight Preterm Infant Bundled Care in the NICU

NCT03370757
View directory record Official record
Conditions
Preterm Infants
Interventions
3-hour bundled care, 6-hour bundled care
Other
Lead sponsor
Duke University
Other
Eligibility
Up to 32 Weeks
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2024 · Synced Oct 20, 2026, 10:16 AM EDT
Withdrawn Not applicable Interventional

Microbiome Survey of Preterm Infants

NCT01942577
View directory record Official record
Conditions
Skin Microbiome
Interventions
NoSting
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plant Based Diet, Ethnicity, and the Gut Microbiome

NCT03314194
View directory record Official record
Conditions
Diet Modification, Microbial Colonization
Interventions
Plant Based Diet
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 20, 2026, 10:16 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microbiome and Axial Spondyloarthritis

NCT04713995
View directory record Official record
Conditions
Axial Spondyloarthritis
Interventions
Dietary recommendations
Other
Lead sponsor
Viome
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Phase 2 Interventional

Acceptability and Feasibility of Apollo in Veterans With a History of PTSD

NCT05019651
View directory record Official record
Conditions
PTSD
Interventions
Apollo Wearable System
Device
Lead sponsor
Lisa Brenner
Federal
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional

Effects of Prebiotic Supplementation and Exercise on Inflammatory Markers, Vascular Function and Cognition in CKD

NCT03689569
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Resistant starch, Exercise, Starch
Dietary Supplement · Behavioral
Lead sponsor
Springfield College
Other
Eligibility
30 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Novel Food Product Containing Microbiota Accessible Carbohydrates on the Human Microbiome

NCT03058575
View directory record Official record
Conditions
Gut Microbiome
Interventions
Dietary MACs, Control
Dietary Supplement · Other
Lead sponsor
Access Business Group
Industry
Eligibility
40 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome

NCT06048809
View directory record Official record
Conditions
Oral Health
Interventions
Stannous Fluoride Toothpaste (Sensodyne Repair and Protect), Regular Fluoride Toothpaste (Colgate Cavity Protection)
Other
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 20, 2026, 10:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer

NCT03304132
View directory record Official record
Conditions
Oral Cancer
Interventions
Classification of Oral Microbiome Using 16S rRNA gene sequence-based approach, Classification of Oral Microbiome Using taxonomic approach
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 92 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude

NCT04111263
View directory record Official record
Conditions
Gastrointestinal Injury, Acute Mountain Sickness
Interventions
FP, Placebo, High altitude, Sea level
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of a Yoga Intervention on Pain and Multiomics in Participants With IBS

NCT04315714
View directory record Official record
Conditions
Irritable Bowel Syndrome, Abdominal Pain
Interventions
Yoga Program
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2021 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Kombucha Consumption on the Microbiome in Healthy Subjects

NCT06484504
View directory record Official record
Conditions
Health Behavior
Interventions
Kombucha beverage
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 20, 2026, 10:16 AM EDT
Completed No phase listed Observational

Molecular and Microbiome/Metagenome Correlates of Recurrent Wheeze in RSV Infected Infants

NCT06424795
View directory record Official record
Conditions
Respiratory Syncytial Virus Infection
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
3 Days to 10 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Results available

The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults

NCT04931836
View directory record Official record
Conditions
Obesity, Overweight, Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Type 2 Diabetes Mellitus, Type 2 Diabetes Mellitus in Obese
Interventions
Physical Activity Intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 64 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MiCrobiome dieT Study

NCT03610477
View directory record Official record
Conditions
Healthy
Interventions
Medium chain triglycerides, Long chain triglycerides
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 20, 2026, 10:16 AM EDT
Not yet recruiting Early Phase 1 Interventional

Characterization of the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of APR-TD011® (RLF-TD011®) Spray Solution

NCT05728879
View directory record Official record
Conditions
Cutaneous T Cell Lymphoma
Interventions
APR-TD011 (RLF-TD011)
Combination Product
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trimethylamine-N-oxide Production and Metabolism

NCT02558673
View directory record Official record
Conditions
Healthy
Interventions
TMAO dietary precursors, Control (or active comparator)
Other
Lead sponsor
Cornell University
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 20, 2026, 10:16 AM EDT
Not listed Not applicable Interventional

Diet as Essential Therapy (DIET) for Inflammatory Bowel Disease

NCT03012542
View directory record Official record
Conditions
Crohn Disease
Interventions
Diet 1, Diet 2
Dietary Supplement
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Oct 20, 2026, 10:16 AM EDT
Terminated Phase 2 Interventional Results available

A Study to Assess Efficacy and Safety of SER-287 in Adults With Active Mild-to-Moderate Ulcerative Colitis

NCT03759041
View directory record Official record
Conditions
Ulcerative Colitis
Interventions
Vancomycin Pre-Treatment, Placebo for Vancomycin Pre-Treatment, SER-287, Placebo for SER-287
Drug
Lead sponsor
Seres Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
81
States / cities
Phoenix, Arizona • North Little Rock, Arkansas • La Jolla, California + 70 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2022 · Synced Oct 20, 2026, 10:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kimchi and Gut Health

NCT07435831
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
60 grams per day of intervention food
Other
Lead sponsor
University of California, Davis
Other
Eligibility
19 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 20, 2026, 10:16 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Aging and Lp299v Study in Healthy Adults

NCT05296395
View directory record Official record
Conditions
Vascular Aging
Interventions
Lactobacillus Plantarum 299v in fermented oat drink, Heat-Killed Placebo control fermented drink
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 10:16 AM EDT