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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:21 AM EDT

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Showing 313–336 of 1,014 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Keiki (Pediatric) Produce Prescription (KPRx) Program Hawaii

NCT05442424
View directory record Official record
Conditions
Malnutrition, Child, Obesity, Food Selection, Nutrition Poor
Interventions
Produce Voucher, Wait-List Control
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
2 Years to 8 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Phase 1Phase 2 Interventional Results available

PRevention Using EPA Against coloREctal Cancer

NCT04216251
View directory record Official record
Conditions
Colorectal Adenoma, Colorectal Cancer, Endoscopic Surgery, Eicosapentaenoic Acid, Gastrointestinal Microbiome
Interventions
AMR101
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atopic Dermatitis (AD) and Food Allergy

NCT03168113
View directory record Official record
Conditions
Atopic Dermatitis (AD), Non-atopic Healthy Controls
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
4 Years to 17 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

NCT05136703
View directory record Official record
Conditions
Depression, HIV-1-infection, Inflammation
Interventions
Cognitive-Behavioral Therapy for Adherence and Depression (CBT-AD), Antiretroviral Therapy (ART) Adherence Counseling
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Coral Gables, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pulse Education and Children

NCT07648446
View directory record Official record
Conditions
Dysbiosis, Cardiometabolic Health Indicators, Education on Feeding and Health Status, Gut Motility
Interventions
Education Only, Education + Pulse Provision, Cooking Class
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Flavonoids on Intestinal Microbiota, Intestinal Inflammation and Metabolic Syndrome

NCT02728570
View directory record Official record
Conditions
Metabolic Syndrome X, Inflammation
Interventions
High Dietary Flavonoids, Low Dietary Flavonoids
Other
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Role of the Gut Microbiome in Complex Regional Pain Syndrome

NCT03612193
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Impaired HIV-associated B Cell and Pneumococcal Vaccine Responses

NCT02012309
View directory record Official record
Conditions
HIV, Pneumococcal Infections, Pneumococcal Vaccines
Interventions
PCV-13, PPSV-23
Biological
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

NCT05821309
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, PEG-3350 with electrolytes, Glycerin
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids

NCT06882772
View directory record Official record
Conditions
Congenital Heart Disease (CHD)
Interventions
2 mL SunButyrate-TG, Placebo, 4 mL SunButyrate-TG
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
1 Month to 3 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analyzing IBS to Identify Biomarkers and Microbiome Signatures

NCT02419963
View directory record Official record
Conditions
Diarrhoea Predominant Irritable Bowel Syndrome, IBS
Interventions
endoscopy for tissue biopsy, Blood Sample, Stool Sample
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption

NCT04066816
View directory record Official record
Conditions
Colo-rectal Cancer, Colon Cancer, Diet Habit
Interventions
Walnuts
Other
Lead sponsor
UConn Health
Other
Eligibility
50 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 22, 2026, 7:21 AM EDT
Completed No phase listed Observational

Identifying Biomarkers of Gastro Intestinal Comorbidities in Autism Spectrum Disorder

NCT07744217
View directory record Official record
Conditions
Autism, Gastro Intestinal Diseases
Interventions
Not listed
Lead sponsor
The Center for Discovery
Other
Eligibility
5 Years to 19 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Harris, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Terminated Phase 2 Interventional Results available

Penn Microbiome Therapy for Recurrent Clostridium Difficile Infection

NCT03973697
View directory record Official record
Conditions
Recurrent Clostridium Difficile Infection
Interventions
Penn Microbiome Therapy - 001, Penn Microbiome Therapy - 002, Penn Microbiome Therapy - 003
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Phase 2 Interventional

Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks

NCT05557279
View directory record Official record
Conditions
Overactive Bladder
Interventions
500 mg NDS-446
Drug
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials

NCT03084003
View directory record Official record
Conditions
Diet Intervention
Interventions
Almonds, Graham crackers
Dietary Supplement
Lead sponsor
University of California, Merced
Other
Eligibility
18 Years to 22 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Merced, California
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gut Kidney Axis in Enteric Hyperoxaluria

NCT05124886
View directory record Official record
Conditions
Enteric Hyperoxaluria
Interventions
Moderately High Oxalate (MOx) Diet
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Active, not recruiting Not applicable Interventional

A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health

NCT07781488
View directory record Official record
Conditions
Gut Health, Microbiome, Bloating, Indigestion, Constipation, Diarrhea, Food Cravings, Abdominal Discomfort, Bowel Movement Irregularity
Interventions
Essential Fibre+
Dietary Supplement
Lead sponsor
Artah Nutrition Limited
Industry
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease

NCT06215222
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome, Healthy, Functional Bloating, Functional Gastrointestinal Disorders
Interventions
Microbiota Sampling
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Phase 2 Interventional

The Female Microbiome in Patients Undergoing Bladder Instillation Therapy

NCT05414305
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome, Microbial Colonization
Interventions
Heparin & Alkalinized Lidocaine Bladder Instillation
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Stool Microbiome Using HyGIeaCare Prep

NCT04264923
View directory record Official record
Conditions
Stool Microbiome
Interventions
HyGIeaCare Prep
Other
Lead sponsor
HyGIeaCare, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Optimizing Overactive Bladder Treatment

NCT03904407
View directory record Official record
Conditions
Overactive Bladder
Interventions
Lactobacillus Probiotic Capsule, Matching Lactobacillus Probiotic Placebo Capsule
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Hillsborough, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed No phase listed Observational

The Microbiome in Parkinson's Disease

NCT03129451
View directory record Official record
Conditions
Parkinson Disease
Interventions
Microbiome specimens in stool
Diagnostic Test
Lead sponsor
Corewell Health West
Other
Eligibility
Not listed
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes

NCT03893422
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
WB-010, WB-011, Placebo
Other
Lead sponsor
Pendulum Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
5
States / cities
Torrance, California • Tustin, California • Youngstown, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Oct 22, 2026, 7:21 AM EDT