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ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:34 AM EDT

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Showing 457–480 of 1,015 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Probiotics on the Shift in Gut Microbiome and Skin Carotenoid Levels

NCT04841694
View directory record Official record
Conditions
Human Microbiome
Interventions
Probiotic
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
40 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 23, 2026, 7:34 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43

NCT02457104
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Obesity
Interventions
Colonoscopy, Weight and diet questionnaire
Procedure · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 59 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2021 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional

Mindfulness-Based Stress Reduction and the Microbiome

NCT01619384
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Irritable Bowel Syndrome
Interventions
Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dairy Fat and Fermentation Study

NCT05840081
View directory record Official record
Conditions
Heart Diseases, Microbial Colonization, Inflammation
Interventions
Milk or yogurt beverage
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Phase 1 Interventional

Livionex Oral Microbiome and Dental Plaque Control in HSCT Recipients

NCT02617407
View directory record Official record
Conditions
Dental Plaque
Interventions
Livionex® Dental Gel, PreviDent 5000 plus/Tom's of Maine Children's toothpaste, Kolibree Toothbrush
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Denver Garden Environment and Microbiome Study Disease

NCT03089151
View directory record Official record
Conditions
Diet Modification, Physical Activity, Weight Gain, Chronic Disease, Lifestyle, Sedentary, Health Behavior
Interventions
Community Garden Intervention
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 23, 2026, 7:34 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Modulating Early Life Microbiome Through Dietary Intervention in Crohn's Disease

NCT03850600
View directory record Official record
Conditions
Crohn Disease, Pregnancy
Interventions
Diet-CD
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
2
States / cities
Worcester, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 23, 2026, 7:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

New Functional Ingredient for Oral Care

NCT07771907
View directory record Official record
Conditions
Oral Health Related Quality of Life (OHRQoL)
Interventions
Botanical A, Botanical B, Vehicle (Placebo solution)
Dietary Supplement
Lead sponsor
Access Business Group
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Phase 1 Interventional

Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties

NCT05675501
View directory record Official record
Conditions
Papulopustular Rosacea
Interventions
Encapsulated Benzoyl Peroxide Cream
Drug
Lead sponsor
Sol-Gel Technologies, Ltd.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 23, 2026, 7:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sources of Bacterial Contamination in Human Milk Samples From the MiLC Trial

NCT03371511
View directory record Official record
Conditions
Bacterial Communities
Interventions
Not listed
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional

Study of Early Enteral Dextrose in Sepsis

NCT03454087
View directory record Official record
Conditions
Sepsis
Interventions
Enteral Dextrose Infusion, Free Water Infusion
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic Supplement and Microbiome, Immune System and Metabolic Syndrome

NCT03201068
View directory record Official record
Conditions
Metabolic Syndrome, Microbiome, Immune Function, Inflammation
Interventions
Probiotic supplement, Placebo
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 23, 2026, 7:34 AM EDT
Withdrawn No phase listed Observational

Microbiome as a ThErapeutic Response Biomarker

NCT04721743
View directory record Official record
Conditions
Uveitis
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
13 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 23, 2026, 7:34 AM EDT
Completed No phase listed Observational

Microbiome in Lung Cancer and Other Malignancies

NCT03688347
View directory record Official record
Conditions
Lung Cancer, Cancer, Malignancy
Interventions
Nasal Swab, Oral Swab, Stool Collection, Microbiome analysis, DNA Banking, Skin Swab
Procedure · Other · Genetic
Lead sponsor
Taher Abu Hejleh
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional

The Gut Microbiome As an Indicator of Readiness for Head & Neck Cancer Surgery

NCT05061316
View directory record Official record
Conditions
Cancer of Head and Neck, Nutrition Aspect of Cancer
Interventions
Nestlé Impact Advanced Recovery
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PREDICT 2: Personalized Responses to Dietary Composition Trial 2

NCT03983733
View directory record Official record
Conditions
Diabetes, Heart Diseases, Diet Habit, Diet Modification, Microbial Colonization, Healthy, Obesity, Metabolism
Interventions
Dietary Intervention
Other
Lead sponsor
Zoe Global Limited
Other
Eligibility
18 Years to 70 Years
Enrollment
1,139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Fecal Microbiota Transplantation in Pediatric Patients

NCT02108821
View directory record Official record
Conditions
Inflammatory Bowel Diseases (IBD), Crohn's Disease (CD), Ulcerative Colitis (UC)
Interventions
Fecal Microbiota Transplantation (FMT)
Biological
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
2 Years to 22 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Early Phase 1 Interventional

Intestinal Microbiome Modification With Resistant Starch in Patients Treated With Dual Immune Checkpoint Inhibitors

NCT04552418
View directory record Official record
Conditions
Solid Tumor
Interventions
Potato starch
Drug
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 23, 2026, 7:34 AM EDT
Not yet recruiting Phase 2 Interventional

PFAS Clinical Trial

NCT07836023
View directory record Official record
Conditions
Environmental Exposure
Interventions
Cholestyramine, Centrum
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 23, 2026, 7:34 AM EDT
Completed No phase listed Observational

Study Assessing Risk Factors for Abdominal Pain in Children With Inflammatory Bowel Disease

NCT02984059
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Genomic DNA, RNA analysis, Microbiome, Calprotectin, Pain questionnaires, Anxiety/Depression Questionnaires
Genetic · Other
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
8 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Oct 23, 2026, 7:34 AM EDT
Recruiting Phase 1Phase 2 Interventional

Intestinal Microbiome Transplant in ALS

NCT07017946
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis ALS
Interventions
MTP-101C
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages

NCT02856776
View directory record Official record
Conditions
Vitamin D Insufficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 23, 2026, 7:34 AM EDT
Terminated No phase listed Observational

Gut and Tumor Microbiome in Patients With Early Stage (II-III), Locally Advanced or Advanced ER-positive and HER2-negative Breast Cancer.

NCT06126003
View directory record Official record
Conditions
Breast Cancer
Interventions
Observation
Other
Lead sponsor
BioCorteX Inc
Industry
Eligibility
18 Years to 85 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Decatur, Illinois • Las Vegas, Nevada • Belleville, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2024 · Synced Oct 23, 2026, 7:34 AM EDT
Completed Phase 1 Interventional

Antibiotics, Gastric Bypass, and the Microbiome

NCT05367479
View directory record Official record
Conditions
Obesity, Morbid, Hypertension, Bariatric Surgery Candidate
Interventions
Antibiotic
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 23, 2026, 7:34 AM EDT